Tracking temporal response dynamics in the ventral striatum during social feedback in anorexia nervosa: A functional magnetic resonance imaging exploratory study.
anorexia nervosa
functional magnetic resonance imaging
reward system
social reward
ventral striatum
Journal
The International journal of eating disorders
ISSN: 1098-108X
Titre abrégé: Int J Eat Disord
Pays: United States
ID NLM: 8111226
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
revised:
26
08
2021
received:
17
02
2021
accepted:
26
08
2021
pubmed:
7
9
2021
medline:
26
10
2021
entrez:
6
9
2021
Statut:
ppublish
Résumé
Research suggests abnormalities in reward-based processes in anorexia nervosa (AN). However, few studies have explored if such alterations might be associated with different temporal activation patterns. This study aims to characterize alterations in time-dependent processes in the ventral striatum (VS) during social feedback in AN using functional magnetic resonance imaging (fMRI). Twenty women with restrictive-subtype AN and 20 age-matched healthy controls (HC) underwent a social judgment experimental fMRI task. Temporal VS hemodynamic responses were extracted in SPM for each participant and each social condition (acceptance/rejection). Compared with age-matched HC, patients with AN showed a significant time by group interaction of peak VS response throughout the task, with a progressive blunting of peak activation responses, accompanied by a progressive increase in baseline activity levels over time. The results suggest an attenuated response pattern to repetitive social rejection in the VS in patients with AN, together with a difficulty in returning to baseline. The information obtained from this study will guide future, design-specific studies to further explore alterations temporal dynamics.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1881-1886Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev). Washington, DC: Author.
Artal, J., & Pérez-Echeverría, M. J. (1986). Validity of the scaled version of the General Health Questionnaire (GHQ-28) in a Spanish population. Psychological Medicine, 16(1), 135-140. https://doi.org/10.1017/S0033291700002579
Cardi, V., Di Matteo, R., Corfield, F., & Treasure, J. (2013). Social reward and rejection sensitivity in eating disorders: An investigation of attentional bias and early experiences. The World Journal of Biological Psychiatry, 14(8), 622-633. https://doi.org/10.3109/15622975.2012.665479
Davey, C. G., Allen, N. B., Harrison, B. J., Dwyer, D. B., & Yücel, M. (2010). Being liked activates primary reward and midline self-related brain regions. Human Brain Mapping, 31(4), 660-668. https://doi.org/10.1002/hbm.20895
Delgado, M. R. (2007). Reward-related responses in the human striatum. Annals of the New York Academy of Sciences, 1104, 70-88. https://doi.org/10.1196/annals.1390.002
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. (2007). Structured clinical interview for DSM-IV axis I disorders-Non-patient edition (SCID-I/NP). New York, NY: Biometrics Research, New York State Psychiatric Institute.
Garner, D. M. (1991). Eating disorder inventory-2: Professional manual. Odessa, FL: Psychological Assessment Resources.
Hamilton, M. (1959). The assessment of anxiety states by rating. British Journal of Medical Psychology, 32(1), 50-55. https://doi.org/10.1111/j.2044-8341.1959.tb00467.x
Hamilton, M. (1960). A rating scale for depression. Journal of Neurology, Neurosurgery, and Psychiatry, 23, 56-62. https://doi.org/10.1136/jnnp.23.1.56
Harrison, B. J., Soriano-Mas, C., Pujol, J., Ortiz, H., López-Solà, M., Hernández-Ribas, R., … Cardoner, N. (2009). Altered corticostriatal functional connectivity in obsessive-compulsive disorder. Archives of General Psychiatry, 66(11), 1189-1200. https://doi.org/10.1001/archgenpsychiatry.2009.152
Kaye, W. H., Fudge, J. L., & Paulus, M. (2009). New insights into symptoms and neurocircuit function of anorexia nervosa. Nature Reviews Neuroscience, 10(8), 573-584. https://doi.org/10.1038/nrn2682
Krach, S., Bodden, M., & Kircher, T. (2010). The rewarding nature of social interactions. Frontiers in Behavioral Neuroscience, 4, 22. https://doi.org/10.3389/fnbeh.2010.00022
Martinez, A. M., & Benavente, R. (1998). The AR face database CVC. (Tech. rep. #24) [Internet]. Retrieved from http://www2.ece.ohio-state.edu/~aleix/ARdatabase.html
Treasure, J., Corfield, F., & Cardi, V. (2012). A three-phase model of the social emotional functioning in eating disorders. European Eating Disorders Review, 20, 431-438. https://doi.org/10.1002/erv.2181
Via, E., Soriano-Mas, C., Sánchez, I., Forcano, L., Harrison, B. J., Davey, C. G., … Cardoner, N. (2015). Abnormal social reward responses in anorexia nervosa: An fmri study. PLoS One, 10(7), e0133539. https://doi.org/10.1371/journal.pone.0133539
Wierenga, C. E., Ely, A., Bischoff-Grethe, A., Bailer, U. F., Simmons, A. N., & Kaye, W. H. (2014). Are extremes of consumption in eating disorders related to an altered balance between reward and inhibition? Frontiers in Behavioral Neuroscience, 8(12), 1-11. https://doi.org/10.3389/fnbeh.2014.00410
Zhu, Y., Hu, X., Wang, J., Chen, J., Guo, Q., Li, C., & Enck, P. (2012). Processing of food, body and emotional stimuli in anorexia nervosa: A systematic review and meta-analysis of functional magnetic resonance imaging studies. European Eating Disorders Review, 20(6), 439-450. https://doi.org/10.1002/erv.2197