Child maltreatment and NR3C1 exon 1

Child Child Abuse / psychology DNA Methylation / genetics Exons Humans Hypothalamo-Hypophyseal System Pituitary-Adrenal System Receptors, Glucocorticoid / genetics
Child maltreatment DNA methylation HPA axis NR3C1 exon 1(F) Psychopathology

Journal

Child abuse & neglect
ISSN: 1873-7757
Titre abrégé: Child Abuse Negl
Pays: England
ID NLM: 7801702

Informations de publication

Date de publication:
12 2021
Historique:
received: 08 10 2020
revised: 10 06 2021
accepted: 26 08 2021
pubmed: 7 9 2021
medline: 19 3 2022
entrez: 6 9 2021
Statut: ppublish

Résumé

Epigenetics offers one promising method for assessing the psychobiological response to stressful experiences during childhood. In particular, deoxyribonucleic acid (DNA) methylation has been associated with an altered hypothalamus-pituitary-adrenal (HPA) axis and the onset of mental disorders. Equally, there are promising leads regarding the association between the methylation of the glucocorticoid receptor gene (NR3C1-1 The current study aimed to assess the evidence of a link among child maltreatment, NR3C1-1 We followed the Prisma guidelines and identified 11 articles that met our inclusion criteria. We found that eight studies (72.72%) reported increased NR3C1-1 NR3C1-1

Sections du résumé

BACKGROUND
Epigenetics offers one promising method for assessing the psychobiological response to stressful experiences during childhood. In particular, deoxyribonucleic acid (DNA) methylation has been associated with an altered hypothalamus-pituitary-adrenal (HPA) axis and the onset of mental disorders. Equally, there are promising leads regarding the association between the methylation of the glucocorticoid receptor gene (NR3C1-1
OBJECTIVE
The current study aimed to assess the evidence of a link among child maltreatment, NR3C1-1
METHODS
We followed the Prisma guidelines and identified 11 articles that met our inclusion criteria.
RESULTS
We found that eight studies (72.72%) reported increased NR3C1-1
CONCLUSION
NR3C1-1

Identifiants

DOI: 10.1016/j.chiabu.2021.105304 PMID: 34488052
pubmed: 34488052
pii: S0145-2134(21)00373-2
doi: 10.1016/j.chiabu.2021.105304
pii:
doi:

Substances chimiques

NR3C1 protein, human 0
Receptors, Glucocorticoid 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

105304

Informations de copyright

Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Auteurs

D L Wadji (DL)

I-Reach Lab, Unit of Clinical and Health Psychology, University of Fribourg, Switzerland. Electronic address: dany.nkonlack@unifr.ch.

T Tandon (T)

I-Reach Lab, Unit of Clinical and Health Psychology, University of Fribourg, Switzerland.

G J M Ketcha Wanda (GJM)

Clinical psychology Lab, Department of Psychology, University of Yaoundé I, Cameroon.

C Wicky (C)

Department of Biology, University of Fribourg, Switzerland.

A Dentz (A)

I-Reach Lab, Unit of Clinical and Health Psychology, University of Fribourg, Switzerland.

G Hasler (G)

Department of Psychiatric, University of Fribourg, Fribourg, Switzerland.

N Morina (N)

Department of Consultant-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Switzerland.

C Martin-Soelch (C)

I-Reach Lab, Unit of Clinical and Health Psychology, University of Fribourg, Switzerland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Sciences sociales › Sociologie › Problèmes sociaux › Violence › Violence domestique › Maltraitance des enfants › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Phénomènes génétiques › Méthylation de l'ADN › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Exons › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Système nerveux › Système neuroendocrinien › Axe hypothalamohypophysaire › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Système endocrine › Glandes endocrines › Axe hypophyso-surrénalien › Child maltreatment and NR3C1 exon 1
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Récepteurs cytoplasmiques et nucléaires › Récepteurs aux glucocorticoïdes › Child maltreatment and NR3C1 exon 1