Effect of 4-Hexylresorcinol on the Efficiency of Antibiotic Treatment of Experimental Sepsis Caused by Antibiotic-Resistant Klebsiella pneumoniae Strain in Mice.
Animals
Animals, Outbred Strains
Anti-Bacterial Agents
/ pharmacology
Disease Models, Animal
Drug Resistance, Multiple, Bacterial
/ drug effects
Drug Synergism
Female
Hexylresorcinol
/ pharmacology
Klebsiella Infections
/ complications
Klebsiella pneumoniae
/ drug effects
Mice
Microbial Sensitivity Tests
Polymyxin B
/ pharmacology
Polymyxins
/ analogs & derivatives
Sepsis
/ drug therapy
4-hexylresorcinol
Klebsiella pneumoniae Pmr
antibiotic resistance
polymyxin
sanified mice
Journal
Bulletin of experimental biology and medicine
ISSN: 1573-8221
Titre abrégé: Bull Exp Biol Med
Pays: United States
ID NLM: 0372557
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
13
11
2020
pubmed:
21
9
2021
medline:
1
2
2022
entrez:
20
9
2021
Statut:
ppublish
Résumé
High efficiency of a combined preparation including synergistic polymyxin B and 4-hexylresorcinol was shown for treatment of experimental sepsis caused by an antibiotic-resistant highly virulent hypermucoid Klebsiella pneumoniae strain KPM9Pm
Identifiants
pubmed: 34542762
doi: 10.1007/s10517-021-05249-6
pii: 10.1007/s10517-021-05249-6
doi:
Substances chimiques
Anti-Bacterial Agents
0
Polymyxins
0
polymyxin B(1)
B35S89JSRU
Polymyxin B
J2VZ07J96K
Hexylresorcinol
R9QTB5E82N
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
458-460Informations de copyright
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.
Références
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doi: 10.1111/cbdd.12478
pubmed: 25393203
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pmcid: 4129256
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doi: 10.1371/journal.pone.0239147
pubmed: 32960928
pmcid: 7508414