Exome sequencing and analysis of 454,787 UK Biobank participants.
Africa
/ ethnology
Asia
/ ethnology
Asthma
/ genetics
Biological Specimen Banks
Databases, Genetic
Diabetes Mellitus
/ genetics
Europe
/ ethnology
Exome
/ genetics
Eye Diseases
/ genetics
Female
Genetic Predisposition to Disease
/ genetics
Genetic Variation
Genome-Wide Association Study
Humans
Hypertension
/ genetics
Liver Diseases
/ genetics
Male
Mutation
Neoplasms
/ genetics
Quantitative Trait, Heritable
United Kingdom
Exome Sequencing
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
received:
09
07
2021
accepted:
06
10
2021
pubmed:
19
10
2021
medline:
5
3
2022
entrez:
18
10
2021
Statut:
ppublish
Résumé
A major goal in human genetics is to use natural variation to understand the phenotypic consequences of altering each protein-coding gene in the genome. Here we used exome sequencing
Identifiants
pubmed: 34662886
doi: 10.1038/s41586-021-04103-z
pii: 10.1038/s41586-021-04103-z
pmc: PMC8596853
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
628-634Subventions
Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021. The Author(s).
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