Pathophysiological interplay between

Animals Ataxin-3 / genetics Disease Models, Animal HEK293 Cells Humans Machado-Joseph Disease / metabolism N-Acetylglucosaminyltransferases / metabolism Peptides Proteasome Endopeptidase Complex Zebrafish / metabolism
Machado–Joseph disease O-GlcNAc OGT Spinocerebellar ataxia type 3 ataxin-3

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
23 11 2021
Historique:
accepted: 28 09 2021
entrez: 17 11 2021
pubmed: 18 11 2021
medline: 22 12 2021
Statut: ppublish

Résumé

Aberrant

Identifiants

DOI: 10.1073/pnas.2025810118 PMID: 34785590 PMC: PMC8617493
pubmed: 34785590
pii: 2025810118
doi: 10.1073/pnas.2025810118
pmc: PMC8617493
pii:
doi:

Substances chimiques

Peptides 0
polyglutamine 26700-71-0
N-Acetylglucosaminyltransferases EC 2.4.1.-
O-GlcNAc transferase EC 2.4.1.-
Ataxin-3 EC 3.4.19.12
Proteasome Endopeptidase Complex EC 3.4.25.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

The authors declare no competing interest.

Références

Brain. 2017 May 1;140(5):1280-1299
pubmed: 28334907
Brain Pathol. 1998 Oct;8(4):669-79
pubmed: 9804376
Nat Commun. 2017 Nov 14;8(1):1491
pubmed: 29133780
J Mol Biol. 2014 Apr 17;426(8):1736-52
pubmed: 24444746
Mol Neurodegener. 2017 May 18;12(1):39
pubmed: 28521765
J Biol Chem. 2006 Jul 21;281(29):20263-70
pubmed: 16714295
Science. 2012 Sep 21;337(6101):1541-6
pubmed: 22878500
Neurobiol Aging. 2018 Oct;70:40-50
pubmed: 29944994
Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10804-9
pubmed: 15249677
Mov Disord. 2011 Mar;26(4):731-5
pubmed: 21506152
Hum Mol Genet. 2011 Jan 1;20(1):141-54
pubmed: 20940148
Prog Neurobiol. 2011 Sep 15;95(1):26-48
pubmed: 21740957
Nat Chem Biol. 2008 Aug;4(8):483-90
pubmed: 18587388
J Biol Chem. 2001 Mar 30;276(13):9838-45
pubmed: 11148210
Nat Neurosci. 2015 Aug;18(8):1183-9
pubmed: 26192747
Front Cell Dev Biol. 2020 Sep 24;8:544043
pubmed: 33072739
Cell Mol Life Sci. 2015 Aug;72(16):3173-83
pubmed: 25840568
Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17669-74
pubmed: 22988095
Biomed Res Int. 2016;2016:6701793
pubmed: 27847820
Cell Rep. 2018 Dec 4;25(10):2878-2890.e4
pubmed: 30517873
J Neurosci. 2017 Aug 9;37(32):7782-7794
pubmed: 28687604
Brain. 2009 Jul;132(Pt 7):1820-32
pubmed: 19451179
Brain Res Bull. 2017 Jul;133:80-87
pubmed: 27497832
Nat Chem Biol. 2012 Feb 26;8(4):393-9
pubmed: 22366723
J Biol Chem. 1984 Mar 10;259(5):3308-17
pubmed: 6421821
Genes Dev. 2017 Aug 15;31(16):1655-1665
pubmed: 28903979
Stem Cell Res. 2018 Jul;30:171-174
pubmed: 29936336
Circ Res. 2015 Jan 30;116(3):504-14
pubmed: 25634973
Neurology. 2002 Mar 12;58(5):702-8
pubmed: 11889231
J Biol Chem. 2014 May 9;289(19):13543-53
pubmed: 24648514
Biomed Res Int. 2019 Feb 14;2019:4741252
pubmed: 30895192
J Biol Chem. 2019 Jan 11;294(2):644-661
pubmed: 30455355
Mol Cell Biol. 2003 Sep;23(18):6469-83
pubmed: 12944474
J Cell Biol. 2006 Apr 10;173(1):19-26
pubmed: 16606690
Sci Rep. 2016 Jun 22;6:28220
pubmed: 27328712
Nat Med. 2013 Aug;19(8):983-97
pubmed: 23921753
Neuropathology. 2018 Apr;38(2):113-124
pubmed: 29218765
Autophagy. 2013 Apr;9(4):604-6
pubmed: 23328586
Hum Mol Genet. 2019 May 1;28(9):1463-1473
pubmed: 30576445
Cell Mol Biol Lett. 2020 Mar 10;25:17
pubmed: 32174982
Nature. 2017 May 4;545(7652):108-111
pubmed: 28445460
Lancet Neurol. 2004 May;3(5):291-304
pubmed: 15099544
Front Neurosci. 2019 May 09;13:473
pubmed: 31143098
Theranostics. 2019 Apr 12;9(8):2183-2197
pubmed: 31149037
J Neurochem. 2018 Jan;144(1):7-34
pubmed: 29049853
J Biol Chem. 2008 Sep 26;283(39):26436-43
pubmed: 18599482
Oxid Med Cell Longev. 2019 Nov 13;2019:6279313
pubmed: 31827688
Nucleic Acids Res. 2001 May 1;29(9):e45
pubmed: 11328886
Nat Cell Biol. 2014 Dec;16(12):1215-26
pubmed: 25419848
Nature. 2007 Apr 26;446(7139):1017-22
pubmed: 17460662
J Neurol. 2007 Jul;254(7):838-45
pubmed: 17468965
Hum Mol Genet. 2008 Feb 1;17(3):431-9
pubmed: 17981811
Nat Commun. 2016 May 11;7:11445
pubmed: 27165717
J Biol Chem. 1997 Apr 4;272(14):9308-15
pubmed: 9083067
Brain. 2010 Jan;133(Pt 1):93-104
pubmed: 20007218
J Biomed Sci. 2019 Oct 21;26(1):80
pubmed: 31630678
Neuron. 2017 Apr 5;94(1):93-107.e6
pubmed: 28384479
Mol Cell. 2015 Apr 2;58(1):47-59
pubmed: 25773598
ACS Chem Biol. 2015 Jun 19;10(6):1392-7
pubmed: 25751766
Biochem Biophys Res Commun. 2007 Oct 26;362(3):734-9
pubmed: 17764659
Nat Chem. 2015 Nov;7(11):913-20
pubmed: 26492012
Int J Mol Sci. 2017 Aug 28;18(9):
pubmed: 28846632
Hum Mol Genet. 2003 Dec 1;12(23):3195-205
pubmed: 14559776
Mol Brain. 2017 Jul 19;10(1):32
pubmed: 28724388
Biochim Biophys Acta. 2014 Sep;1842(9):1333-9
pubmed: 24859566
Brain Sci. 2020 Dec 09;10(12):
pubmed: 33317171
Dis Model Mech. 2021 Oct 1;14(10):
pubmed: 34473252
PLoS Biol. 2016 Nov 16;14(11):e2000733
pubmed: 27851749

Auteurs

Priscila Pereira Sena (P)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.
Graduate School of Cellular Neuroscience, University of Tübingen, Tübingen 72074, Germany.
ORCID: 0000-0002-2061-5470

Jonasz J Weber (JJ)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.
Department of Human Genetics, Ruhr-University Bochum, Bochum 44801, Germany.
ORCID: 0000-0003-3758-1569

Maxinne Watchon (M)

Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW 2109, Australia.
ORCID: 0000-0002-8400-4994

Katherine J Robinson (KJ)

Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW 2109, Australia.
ORCID: 0000-0001-9603-2696

Zinah Wassouf (Z)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.

Stefan Hauser (S)

German Center for Neurodegenerative Diseases, Tübingen 72076, Germany.
Department of Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany.
ORCID: 0000-0002-1022-7482

Jacob Helm (J)

German Center for Neurodegenerative Diseases, Tübingen 72076, Germany.
Department of Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany.

Mahkameh Abeditashi (M)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.
Graduate School of Cellular Neuroscience, University of Tübingen, Tübingen 72074, Germany.

Jana Schmidt (J)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.

Jeannette Hübener-Schmid (J)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.
ORCID: 0000-0002-4973-0923

Ludger Schöls (L)

German Center for Neurodegenerative Diseases, Tübingen 72076, Germany.
Department of Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany.

Angela S Laird (AS)

Centre for Motor Neuron Disease Research, Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW 2109, Australia.

Olaf Riess (O)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.
ORCID: 0000-0002-7011-1369

Thorsten Schmidt (T)

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen 72076, Germany; Thorsten.Schmidt@med.uni-tuebingen.de.
Center for Rare Diseases, University of Tübingen, Tübingen 72076, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Pathophysiological interplay between
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines nucléaires › Ataxines › Ataxine-3 › Pathophysiological interplay between
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Pathophysiological interplay between
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Pathophysiological interplay between
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pathophysiological interplay between
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Maladies neurodégénératives héréditaires › Dégénérescences spinocérébelleuses › Ataxies spinocérébelleuses › Maladie de Machado-Joseph › Pathophysiological interplay between
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Glycosyltransferase › N-acetylhexosaminyltransferase › N-acetylglucosaminyltransferase › Pathophysiological interplay between
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Pathophysiological interplay between
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Complexes multienzymatiques › Proteasome endopeptidase complex › Pathophysiological interplay between
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › Pathophysiological interplay between