Adaptation to Antimicrobials and Pathogenicity in Mycoplasmas: Development of Ciprofloxacin-Resistance and Evolution of Virulence in Acholeplasma laidlawii.
Acholeplasma laidlawii
Drosophila melanogaster
ciprofloxacin-resistant strains
genomic profile
phenotypic resistance
vesicular proteome
virulence
virulome
Journal
Doklady. Biochemistry and biophysics
ISSN: 1608-3091
Titre abrégé: Dokl Biochem Biophys
Pays: United States
ID NLM: 101126895
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
10
08
2021
accepted:
03
09
2021
revised:
02
09
2021
entrez:
30
12
2021
pubmed:
31
12
2021
medline:
12
2
2022
Statut:
ppublish
Résumé
For the first time it was shown that the development of resistance to ciprofloxacin in vitro in Acholeplasma laidlawii, a mycoplasma which is widely spread in nature and which is the main contaminant of cell cultures and vaccines, is associated with diverse pathways of virulence evolution: virulome and virulence differ significantly between ciprofloxacin-resistant strains, including those with the same level of antimicrobial resistance.
Identifiants
pubmed: 34966969
doi: 10.1134/S1607672921060028
pii: 10.1134/S1607672921060028
doi:
Substances chimiques
Anti-Infective Agents
0
Ciprofloxacin
5E8K9I0O4U
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
444-448Informations de copyright
© 2021. Pleiades Publishing, Ltd.
Références
Turner, W.C., Kamath, P.L., van Heerden, H., et al., R. Soc. Open Sci., 2021, vol. 8, art. 210088.
doi: 10.1098/rsos.210088
Pan, Y., Zeng, J., Li, L., et al., mSystems, 2020, vol. 5, no. 3, art. e00821-19.
doi: 10.1128/mSystems.00821-19
Hochachka, W.M., Dhondt, A.A., Dobson, A., et al., Proc. Biol. Sci., 2013, vol. 280, art. 20131068.
pubmed: 23843387
pmcid: 3730588
Faucher, M., Nouvel, L.-X., Dordet-Frisoni, E., et al., PLoS Genet., 2019, vol. 15, no. 1, art. e1007910.
doi: 10.1371/journal.pgen.1007910
Chernova, O.A., Chernov, V.M., Mouzykantov, A.A., et al., Int. J. Antimicrob. Agents, 2021, vol. 57, art. 106253.
doi: 10.1016/j.ijantimicag.2020.106253
Mouzykantov, A.A., Medvedeva, E.S., Baranova, N.B., et al., Data Brief, 2020, vol. 33, art. 106412.
doi: 10.1016/j.dib.2020.106412
Chernov, V.M., Mouzykantov, A.A., Baranova, N.B., et al., J. Proteomics, 2014, vol. 110, pp. 117–128.
doi: 10.1016/j.jprot.2014.07.020
Qiao, H., Keesey, I.W., Hansson, B.S., and Knaden, M., J. Exp. Biol., 2019, vol. 222, part 5, art. jeb192500.
doi: 10.1242/jeb.192500
Sullivan, W., Ashburner, M., and Hawley, E.S., Drosophila Protocols, New York: Cold Spring Harbour Press, 2000.
Mukhopadhyay, I., Chowdhuri, D.K., Bajpayee, M., et al., Mutagenesis, 2004, vol. 19, pp. 85–90.
doi: 10.1093/mutage/geh007
Kang, D. and Douglas, A.E., Biol. Lett., 2020, vol. 16, no. 2, art. 20190803.
doi: 10.1098/rsbl.2019.0803
Ventura, I.M., Martins, A.B., Lyra, M.L., et al., Microb. Ecol., 2012, vol. 64, pp. 794–801.
doi: 10.1007/s00248-012-0054-6
Rudman, S.M., Greenblum, S., Hughes, R.C., et al., Proc. Natl. Acad. Sci. U. S. A., 2019, vol. 116, pp. 20025–20032.
doi: 10.1073/pnas.1907787116
Rakovskaya, I.V., Ermolaeva, S.A., Levina, G.A., et al., J. Med. Microbiol., 2019, vol. 68, pp. 1747–1758.
doi: 10.1099/jmm.0.001081