Modulation of the Directionality of Hole Transfer between the Base and the Sugar-Phosphate Backbone in DNA with the Number of Sulfur Atoms in the Phosphate Group.


Journal

The journal of physical chemistry. B
ISSN: 1520-5207
Titre abrégé: J Phys Chem B
Pays: United States
ID NLM: 101157530

Informations de publication

Date de publication:
20 01 2022
Historique:
pubmed: 7 1 2022
medline: 22 2 2022
entrez: 6 1 2022
Statut: ppublish

Résumé

This work shows that S atom substitution in phosphate controls the directionality of hole transfer processes between the base and sugar-phosphate backbone in DNA systems. The investigation combines synthesis, electron spin resonance (ESR) studies in supercooled homogeneous solution, pulse radiolysis in aqueous solution at ambient temperature, and density functional theory (DFT) calculations of in-house synthesized model compound dimethylphosphorothioate (DMTP(O

Identifiants

pubmed: 34990129
doi: 10.1021/acs.jpcb.1c09068
pmc: PMC8776618
mid: NIHMS1770105
doi:

Substances chimiques

Phosphates 0
Sugars 0
Sulfur 70FD1KFU70
DNA 9007-49-2

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

430-442

Subventions

Organisme : NCI NIH HHS
ID : R01 CA045424
Pays : United States
Organisme : NCI NIH HHS
ID : R15 CA111329
Pays : United States

Références

Chemosphere. 2019 Apr;220:1014-1032
pubmed: 33395788
ACS Omega. 2021 Jun 14;6(25):16600-16611
pubmed: 34235332
Chem Soc Rev. 2011 Mar;40(3):1368-82
pubmed: 21221459
Int J Radiat Biol. 2000 Sep;76(9):1157-66
pubmed: 10993627
J Phys Chem B. 2012 May 24;116(20):5900-6
pubmed: 22553971
J Phys Chem B. 2007 Jun 28;111(25):7415-21
pubmed: 17547448
Nat Rev Genet. 2001 Mar;2(3):196-206
pubmed: 11256071
J Phys Chem B. 2006 Nov 30;110(47):24171-80
pubmed: 17125389
J Org Chem. 2002 Oct 18;67(21):7267-74
pubmed: 12375953
DNA Repair (Amst). 2008 Sep 1;7(9):1413-25
pubmed: 18603018
Chem Rev. 2010 Mar 10;110(3):1642-62
pubmed: 20214403
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Oct;52(4):577-87
pubmed: 3499410
Chemistry. 2000 Feb 4;6(3):475-84
pubmed: 10747414
Nucleic Acids Res. 2004 Dec 15;32(22):6565-74
pubmed: 15601999
Environ Sci Pollut Res Int. 2021 Aug;28(31):41552-41575
pubmed: 34086177
Angew Chem Int Ed Engl. 2021 Aug 23;60(35):19102-19106
pubmed: 34173696
Int J Mol Sci. 2019 Oct 08;20(19):
pubmed: 31597345
J Phys Chem A. 2020 Jul 23;124(29):6076-6083
pubmed: 32585092
Nucleic Acids Res. 2006 Mar 14;34(5):1501-11
pubmed: 16537838
J Am Chem Soc. 2013 Aug 28;135(34):12827-38
pubmed: 23885974
Phys Chem Chem Phys. 2010;12(20):5353-68
pubmed: 21491657
J Phys Chem B. 2010 Jun 10;114(22):7672-80
pubmed: 20469885
J Am Chem Soc. 2014 Apr 23;136(16):5956-62
pubmed: 24689701
Chem Rev. 2010 Dec 8;110(12):7002-23
pubmed: 20443634
RSC Chem Biol. 2020 Dec 8;2(1):94-150
pubmed: 34458777
Cold Spring Harb Symp Quant Biol. 2000;65:377-82
pubmed: 12760053
J Am Chem Soc. 2011 Mar 30;133(12):4527-37
pubmed: 21381665
Nucleic Acids Res. 2005 Oct 04;33(17):5553-64
pubmed: 16204456
Annu Rev Biophys Biophys Chem. 1987;16:93-114
pubmed: 3297093
Arch Biochem Biophys. 1993 Feb 1;300(2):535-43
pubmed: 8434935
J Am Chem Soc. 2009 Apr 15;131(14):5203-7
pubmed: 19320486
Radiat Res. 1981 Dec;88(3):524-32
pubmed: 7031753
Phys Chem Chem Phys. 2021 Sep 29;23(37):21148-21162
pubmed: 34528029
Chemistry. 2020 Aug 3;26(43):9495-9505
pubmed: 32059063
J Am Chem Soc. 2009 Jun 24;131(24):8614-9
pubmed: 19469533
Cold Spring Harb Perspect Biol. 2013 Feb 01;5(2):
pubmed: 23378590
J Mol Biol. 1997 Apr 25;268(1):118-36
pubmed: 9149146
J Am Chem Soc. 2003 Aug 27;125(34):10213-8
pubmed: 12926943
Free Radic Res. 2012 Apr;46(4):382-419
pubmed: 22276778
J Phys Chem Lett. 2018 Sep 6;9(17):5105-5109
pubmed: 30132673
FEMS Microbiol Rev. 2019 Mar 1;43(2):109-122
pubmed: 30289455
Chem Soc Rev. 2021 Aug 7;50(15):8355-8360
pubmed: 34128512
Phys Chem Chem Phys. 2018 May 30;20(21):14927-14937
pubmed: 29786710
Nucleic Acid Ther. 2014 Dec;24(6):374-87
pubmed: 25353652
Nat Chem Biol. 2007 Nov;3(11):689-90
pubmed: 17948013
Acc Chem Res. 2010 Feb 16;43(2):280-7
pubmed: 19938827
Radiat Res. 1997 Jun;147(6):663-73
pubmed: 9189163
Mol Med Rep. 2017 Aug;16(2):2089-2094
pubmed: 28627628
Nucleic Acids Res. 2019 Dec 16;47(22):11514-11526
pubmed: 31724721
Radiat Res. 2006 Apr;165(4):479-84
pubmed: 16579661

Auteurs

Sergey A Denisov (SA)

Institut de Chimie Physique, UMR 8000 CNRS/Université Paris-Saclay, Bât. 349, Orsay 91405 Cedex, France.

Samuel Ward (S)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Viacheslav Shcherbakov (V)

Institut de Chimie Physique, UMR 8000 CNRS/Université Paris-Saclay, Bât. 349, Orsay 91405 Cedex, France.

Alexander D Stark (AD)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Renata Kaczmarek (R)

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, Łódź 90-363, Poland.

Ewa Radzikowska-Cieciura (E)

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, Łódź 90-363, Poland.

Dipra Debnath (D)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Taisiya Jacobs (T)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Anil Kumar (A)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Michael D Sevilla (MD)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

Pascal Pernot (P)

Institut de Chimie Physique, UMR 8000 CNRS/Université Paris-Saclay, Bât. 349, Orsay 91405 Cedex, France.

Roman Dembinski (R)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.
Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, Łódź 90-363, Poland.

Mehran Mostafavi (M)

Institut de Chimie Physique, UMR 8000 CNRS/Université Paris-Saclay, Bât. 349, Orsay 91405 Cedex, France.

Amitava Adhikary (A)

Department of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.

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Classifications MeSH