Functional impact and targetability of
Adult
Animals
Cell Line, Tumor
Child
Chromogranins
GTP-Binding Protein alpha Subunits, Gs
Humans
Mice
Mutation
MyoD Protein
/ genetics
Oncogenes
PTEN Phosphohydrolase
/ genetics
Phosphatidylinositol 3-Kinases
/ genetics
Proto-Oncogene Proteins c-akt
/ genetics
Rhabdomyosarcoma
/ genetics
Transcription Factors
rhabdomyosarcoma
Journal
Cold Spring Harbor molecular case studies
ISSN: 2373-2873
Titre abrégé: Cold Spring Harb Mol Case Stud
Pays: United States
ID NLM: 101660017
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
received:
05
08
2021
accepted:
06
12
2021
entrez:
11
1
2022
pubmed:
12
1
2022
medline:
27
1
2022
Statut:
epublish
Résumé
Spindle cell/sclerosing rhabdomyosarcoma (ssRMS) is a rare subtype of rhabdomyosarcoma, commonly harboring a gain-of-function L122R mutation in the muscle-specific master transcription factor MYOD1.
Identifiants
pubmed: 35012940
pii: mcs.a006140
doi: 10.1101/mcs.a006140
pmc: PMC8744497
pii:
doi:
Substances chimiques
Chromogranins
0
MyoD Protein
0
MyoD1 myogenic differentiation protein
0
PI3KCA protein, human
0
Transcription Factors
0
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
PTEN Phosphohydrolase
EC 3.1.3.67
PTEN protein, human
EC 3.1.3.67
GNAS protein, human
EC 3.6.1.-
GTP-Binding Protein alpha Subunits, Gs
EC 3.6.5.1
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2022 Choo et al.; Published by Cold Spring Harbor Laboratory Press.
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