A method to construct the dynamic landscape of a bio-membrane with experiment and simulation.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
10 01 2022
10 01 2022
Historique:
received:
21
06
2021
accepted:
11
11
2021
entrez:
11
1
2022
pubmed:
12
1
2022
medline:
27
1
2022
Statut:
epublish
Résumé
Biomolecular function is based on a complex hierarchy of molecular motions. While biophysical methods can reveal details of specific motions, a concept for the comprehensive description of molecular dynamics over a wide range of correlation times has been unattainable. Here, we report an approach to construct the dynamic landscape of biomolecules, which describes the aggregate influence of multiple motions acting on various timescales and on multiple positions in the molecule. To this end, we use
Identifiants
pubmed: 35013165
doi: 10.1038/s41467-021-27417-y
pii: 10.1038/s41467-021-27417-y
pmc: PMC8748619
doi:
Substances chimiques
Buffers
0
Carbon Isotopes
0
Lipid Bilayers
0
Membranes, Artificial
0
Phosphatidylcholines
0
Solutions
0
1-palmitoyl-2-oleoylphosphatidylcholine
TE895536Y5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
108Informations de copyright
© 2022. The Author(s).
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