Bioengineering for the industrial production of 2,3-butanediol by the yeast, Saccharomyces cerevisiae.
2,3-Butanediol production
Biological process
Fermentation
Metabolic engineering
Microorganisms
Recovery of 2,3- butanediol
Saccharomyces cerevisiae
Journal
World journal of microbiology & biotechnology
ISSN: 1573-0972
Titre abrégé: World J Microbiol Biotechnol
Pays: Germany
ID NLM: 9012472
Informations de publication
Date de publication:
12 Jan 2022
12 Jan 2022
Historique:
received:
18
10
2021
accepted:
29
12
2021
entrez:
12
1
2022
pubmed:
13
1
2022
medline:
19
1
2022
Statut:
epublish
Résumé
Owing to issues, such as the depletion of petroleum resources and price instability, the development of biorefinery related technologies that produce fuels, electric power, chemical substances, among others, from renewable resources is being actively promoted. 2,3-Butanediol (2,3-BDO) is a key compound that can be used to produce various chemical substances. In recent years, 2,3-BDO production using biological processes has attracted extensive attention for achieving a sustainable society through the production of useful compounds from renewable resources. With the development of genetic engineering, metabolic engineering, synthetic biology, and other research field, studies on 2,3-BDO production by the yeast, Saccharomyces cerevisiae, which is safe and can be fabricated using an established industrial-scale cultivation technology, have been actively conducted. In this review, we sought to describe 2,3-BDO and its derivatives; discuss 2,3-BDO production by microorganisms, in particular S. cerevisiae, whose research and development has made remarkable progress; describe a method for separating and recovering 2,3-BDO from a microbial culture medium; and propose future prospects for the industrial production of 2,3-BDO by microorganisms.
Identifiants
pubmed: 35018511
doi: 10.1007/s11274-021-03224-x
pii: 10.1007/s11274-021-03224-x
doi:
Substances chimiques
Butylene Glycols
0
Culture Media
0
Ethanol
3K9958V90M
2,3-butylene glycol
45427ZB5IJ
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
38Subventions
Organisme : Japan Society for the Promotion of Science
ID : JP20J15573
Organisme : Japan Society for the Promotion of Science
ID : JP18K14069
Organisme : Japan Society for the Promotion of Science
ID : JP18KK0413
Organisme : Japan Science and Technology Agency
ID : JPMJPR20KB
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature B.V.
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