Is it safe to perform an anastomosis for rectal cancer after prostate cancer? A multicentre study of 126 patients from the GRECCAR group.
delayed coloanal anastomosis
prostate cancer
radiotherapy
rectal cancer
restorative surgery
Journal
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
ISSN: 1463-1318
Titre abrégé: Colorectal Dis
Pays: England
ID NLM: 100883611
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
revised:
28
10
2021
received:
31
08
2021
accepted:
08
01
2022
pubmed:
18
1
2022
medline:
3
6
2022
entrez:
17
1
2022
Statut:
ppublish
Résumé
To determine the safety of performing an anastomosis after rectal cancer (RC) resection in patients with a previously treated prostate cancer (PC). Patients with a previously treated PC who underwent rectal resection from 2008 to 2018 were retrospectively included. Outcomes were compared between patients who underwent rectal resection with anastomosis (restorative surgery, RS+ group) and those with a definitive stoma (RS- group). In the RS+ group, anastomotic leak (AL) rates were assessed according to the type of reconstruction. A total of 126 patients underwent rectal surgery for mid-low RC after a previous PC treated by radiotherapy (RT) and/or radical prostatectomy. Overall, 80 patients (63%) underwent a RS and 46 patients (37%) underwent rectal surgery with a definitive stoma. There was no statistical difference between the two groups in terms of intraoperative data, except for the type of resection with more multivisceral resection in the RS- group (p < 0.01). In the RS+group, a diverting stoma was performed in 74% of cases. No difference between the two groups in terms of overall morbidity was found. In the RS+group (n = 80), 17 patients (21%) experienced AL. Of these, none was observed when delayed coloanal anastomosis was performed (p = 0.16). Long-term permanent stoma in the RS+ group was 16% (n = 13). Restorative surgery after resection for RC in patients with a previous history of RT and/or radical prostatectomy for PC is safe without additional morbidity. In selected patients for restorative surgery, performing delayed coloanal anastomosis may represent a promising option.
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
594-600Informations de copyright
© 2022 The Association of Coloproctology of Great Britain and Ireland.
Références
Nash GF, Turner KJ, Hickish T, Smith J, Chand M, Moran BJ. Interactions in the aetiology, presentation and management of synchronous and metachronous adenocarcinoma of the prostate and rectum. Ann R Coll Surg Engl. 2012;94(7):456-62.
NICE Guidance. Prostate cancer: diagnosis and management: (c) NICE (2019) Prostate cancer: diagnosis and management. BJU Int. 2019;124(1):9-26.
Mirnezami A, Mirnezami R, Chandrakumaran K, Sasapu K, Sagar P, Finan P. Increased local recurrence and reduced survival from colorectal cancer following anastomotic leak: systematic review and meta-analysis. Ann Surg. 2011;253(5):890-9.
Moon K, Stukenborg GJ, Keim J, Theodorescu D. Cancer incidence after localized therapy for prostate cancer. Cancer. 2006;107(5):991-8.
Lakkis Z, Vernerey D, Mege D, Faucheron J-L, Panis Y, Tuech J-J, et al. Morbidity and oncological outcomes of rectal cancer impaired by previous prostate malignancy. Br J Surg. 2019;106(8):1087-98.
Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205-13.
Rahbari NN, Weitz J, Hohenberger W, Heald RJ, Moran B, Ulrich A, et al. Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery. 2010;147(3):339-51.
D'Amico AV, Whittington R, Malkowicz SB, Schultz D, Blank K, Broderick GA, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA. 1998;280(11):969-74.
Bosset JF, Collette L, Calais G, Mineur L, Maingon P, Radosevic-Jelic L, et al. Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med. 2006;355(11):1114-23.
Kapiteijn E, Marijnen CA, Nagtegaal ID, Putter H, Steup WH, Wiggers T, et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med. 2001;345(9):638-46.
Heald RJ, Husband EM, Ryall RD. The mesorectum in rectal cancer surgery-the clue to pelvic recurrence? Br J Surg. 1982;69(10):613-6.
Lakkis Z, Manceau G, Bridoux V, Brouquet A, Kirzin S, Maggiori L, et al. Management of rectal cancer: the 2016 French guidelines. Colorectal Dis. 2017;19(2):115-22.
Gustafsson UO, Scott MJ, Hubner M, Nygren J, Demartines N, Francis N, et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS((R))) Society Recommendations: 2018. World J Surg. 2019;43(3):659-95.
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet. 2007;370(9596):1453-7.
Sverrisson I, Folkvaljon F, Chabok A, Stattin P, Smedh K, Nikberg M. Anastomotic leakage after anterior resection in patients with rectal cancer previously irradiated for prostate cancer. Eur J Surg Oncol. 2019;45(3):341-6.
Francois MO, Buscail E, Vendrely V, Célérier B, Assénat V, Moreau J-B, et al. Delayed coloanal anastomosis: an alternative option for restorative rectal cancer surgery after high-dose pelvic radiotherapy for prostate cancer. Colorectal Dis. 2020;22(11):1545-52.
Yeh CY, Changchien CR, Wang JY, Chen J-S, Chen HH, Chiang J-M, et al. Pelvic drainage and other risk factors for leakage after elective anterior resection in rectal cancer patients: a prospective study of 978 patients. Ann Surg. 2005;241(1):9-13.
Peeters KC, Tollenaar RA, Marijnen CA, Klein Kranenbarg E, Steup WH, Wiggers T, et al. Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg. 2005;92(2):211-6.
Bertelsen CA, Andreasen AH, Jorgensen T, Harling H. Anastomotic leakage after anterior resection for rectal cancer: risk factors. Colorectal Dis. 2010;12(1):37-43.
Matthiessen P, Hallbook O, Andersson M, Rutegard J, Sjodahl R. Risk factors for anastomotic leakage after anterior resection of the rectum. Colorectal Dis. 2004;6(6):462-9.
Branagan G, Finnis D, Wessex Colorectal Cancer Audit Working G. Prognosis after anastomotic leakage in colorectal surgery. Dis Colon Rectum. 2005;48(5):1021-6.
Denost Q, Rouanet P, Faucheron JL, Panis Y, Meunier B, Cotte E, et al. To drain or not to drain infraperitoneal anastomosis after rectal excision for cancer: The GRECCAR 5 randomized trial. Ann Surg. 2017;265(3):474-80.
van der Pas MH, Haglind E, Cuesta MA, Fürst A, Lacy AM, Hop WCJ, et al. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol. 2013;14(3):210-8.
Lefevre JH, Mineur L, Kotti S, Rullier E, Rouanet P, de Chaisemartin C, et al. Effect of Interval (7 or 11 weeks) between neoadjuvant radiochemotherapy and surgery on complete pathologic response in rectal cancer: a multicenter, randomized, controlled trial (GRECCAR-6). J Clin Oncol. 2016;34(31):3773-80.
Buscail E, Blondeau V, Adam JP, Pontallier A, Laurent C, Rullier E, et al. Surgery for rectal cancer after high-dose radiotherapy for prostate cancer: is sphincter preservation relevant? Colorectal Dis. 2015;17(11):973-9.
Cutait DE, Figliolini FJ. A new method of colorectal anastomosis in abdominoperineal resection. Dis Colon Rectum. 1961;4:335-42.
Turnbull RB Jr, Cuthbertson A. Abdominorectal pull-through resection for cancer and for Hirschsprung's disease. Delayed posterior colorectal anastomosis. Cleve Clin Q. 1961;28:109-15.
Biondo S, Trenti L, Espin E, Bianco F, Barrios O, Falato A, et al. Two-stage turnbull-cutait pull-through coloanal anastomosis for low rectal cancer: a randomized clinical trial. JAMA Surg. 2020;155(8):e201625.
Hallet J, Milot H, Drolet S, Desrosiers E, Grégoire RC, Bouchard A. The clinical results of the Turnbull-Cutait delayed coloanal anastomosis: a systematic review. Tech Coloproctol. 2014;18(6):579-90.
Remzi FH, El Gazzaz G, Kiran RP, Kirat HT, Fazio VW. Outcomes following Turnbull-Cutait abdominoperineal pull-through compared with coloanal anastomosis. Br J Surg. 2009;96(4):424-9.
Hain E, Maggiori L, Manceau G, Mongin C, Prost à la Denise J, Panis Y. Oncological impact of anastomotic leakage after laparoscopic mesorectal excision. Br J Surg. 2017;104(3):288-95.
Portale G, Popesc GO, Parotto M, Cavallin F. Delayed colo-anal anastomosis for rectal cancer: pelvic morbidity, functional results and oncological outcomes: a systematic review. World J Surg. 2019;43(5):1360-9.