Coenzymes and the primary and specialized metabolism interface.
B vitamins
Coenzymes
Enzymes
Primary metabolism
Specialized metabolism
Journal
Current opinion in plant biology
ISSN: 1879-0356
Titre abrégé: Curr Opin Plant Biol
Pays: England
ID NLM: 100883395
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
17
10
2021
revised:
06
12
2021
accepted:
20
12
2021
pubmed:
23
1
2022
medline:
19
4
2022
entrez:
22
1
2022
Statut:
ppublish
Résumé
In plants, primary and specialized metabolism have classically been distinguished as either essential for growth or required for survival in a particular environment. Coenzymes (organic cofactors) are essential for growth but their importance to specialized metabolism is often not considered. In line with the recent proposal of viewing primary and specialized metabolism as an integrated whole rather than segregated lots with a defined interface, we highlight here the importance of collating information on the regulation of coenzyme supply with metabolic demands using examples of vitamin B derived coenzymes. We emphasize that coenzymes can have enormous influence on the outcome of metabolic as well as engineered pathways and should be taken into account in the era of synthetic biology.
Identifiants
pubmed: 35063913
pii: S1369-5266(21)00172-2
doi: 10.1016/j.pbi.2021.102170
pii:
doi:
Substances chimiques
Coenzymes
0
Vitamin B Complex
12001-76-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
102170Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.