Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.
R2-like ligand-binding oxidase
R2lox
aldehyde deformylating oxygenase
ferritin-like protein
hydroxy fatty acids
long-chain fatty acids
Journal
FEBS letters
ISSN: 1873-3468
Titre abrégé: FEBS Lett
Pays: England
ID NLM: 0155157
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
revised:
10
02
2022
received:
11
12
2021
accepted:
14
02
2022
pubmed:
18
2
2022
medline:
30
6
2022
entrez:
17
2
2022
Statut:
ppublish
Résumé
R2-like ligand-binding oxidase (R2lox) is a ferritin-like protein that harbours a heterodinuclear manganese-iron active site. Although R2lox function is yet to be established, the enzyme binds a fatty acid ligand coordinating the metal centre and catalyses the formation of a tyrosine-valine ether cross-link in the protein scaffold upon O
Identifiants
pubmed: 35175627
doi: 10.1002/1873-3468.14319
pmc: PMC9314684
doi:
Substances chimiques
Ligands
0
Manganese
42Z2K6ZL8P
Iron
E1UOL152H7
Oxidoreductases
EC 1.-
Banques de données
RefSeq
['WP_011277966', 'WP_009945174', 'yp_148624', 'WP_011278976']
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1600-1610Informations de copyright
© 2022 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
Références
Nucleic Acids Res. 2016 Jul 8;44(W1):W344-50
pubmed: 27166375
J Am Chem Soc. 2014 Sep 24;136(38):13399-409
pubmed: 25153930
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):303-12
pubmed: 21460448
Science. 2004 Jul 9;305(5681):245-8
pubmed: 15247479
Annu Rev Biochem. 2019 Jun 20;88:409-431
pubmed: 30633550
Extremophiles. 2020 Jul;24(4):475-483
pubmed: 32328734
Nat Commun. 2020 Mar 23;11(1):1525
pubmed: 32251275
Science. 2011 May 20;332(6032):929
pubmed: 21596985
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32
pubmed: 20124692
Nutrients. 2016 Jan 04;8(1):
pubmed: 26742061
J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674
pubmed: 19461840
J Inorg Biochem. 2016 Sep;162:164-177
pubmed: 27138102
Front Bioeng Biotechnol. 2019 Dec 10;7:408
pubmed: 31921813
Science. 2020 Apr 24;368(6489):424-427
pubmed: 32217749
Protein Sci. 2018 Jan;27(1):293-315
pubmed: 29067766
Chem Biodivers. 2012 Sep;9(9):1981-8
pubmed: 22976985
J Biol Chem. 2012 Jun 8;287(24):20565-75
pubmed: 22535960
Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12863-5
pubmed: 11698675
J Pharm (Cairo). 2013;2013:874875
pubmed: 26555998
Metab Eng. 2008 Nov;10(6):333-9
pubmed: 18812230
Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1074-80
pubmed: 19770504
Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17189-94
pubmed: 24101498
Biotechnol Bioeng. 2018 Oct;115(10):2576-2584
pubmed: 30063082
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W299-302
pubmed: 15980475
Biochemistry. 2020 Oct 13;59(40):3834-3843
pubmed: 32935984
Biochim Biophys Acta. 2015 Jan;1854(1):65-72
pubmed: 25448017
J Biol Chem. 2015 Oct 16;290(42):25254-72
pubmed: 26324712
Science. 2010 Jul 30;329(5991):559-62
pubmed: 20671186
J Biol Inorg Chem. 2010 Mar;15(3):339-49
pubmed: 20225400
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5633-8
pubmed: 19321420
Acta Crystallogr D Struct Biol. 2019 Oct 1;75(Pt 10):861-877
pubmed: 31588918
FEBS Lett. 2003 Sep 25;552(2-3):135-40
pubmed: 14527675
Arch Biochem Biophys. 2018 Apr 2;643:14-23
pubmed: 29462588
Chembiochem. 2013 Jul 8;14(10):1204-8
pubmed: 23757044
Science. 2007 May 25;316(5828):1188-91
pubmed: 17525338
J Biol Chem. 2019 Nov 29;294(48):18372-18386
pubmed: 31591267
Biochemistry. 2017 Jul 5;56(26):3369-3379
pubmed: 28574263
Front Microbiol. 2016 Oct 04;7:1561
pubmed: 27757104
Sci Adv. 2019 Aug 07;5(8):eaax4621
pubmed: 31457106