Chemical Constituents of the Roots of Schisandra chinensis.
Magnoliaceae
Schisandra chinensis
neuroprotective effect
phenylpropanoid
sesquiterpene
Journal
Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
06
12
2021
accepted:
24
02
2022
pubmed:
27
2
2022
medline:
23
4
2022
entrez:
26
2
2022
Statut:
ppublish
Résumé
One new phenylpropanoid schineolignin D (1), one new sesquiterpene (-)-(7S,10S)-3,11,12,13-tetrahydroxycalamenene (2), one new quinic acid 4-(E)-O-coumaroylquinic acid ethyl ester (3), and seven known compounds 4-10 were separated from the roots of Schisandra chinensis. The chemical structures of all compounds were characterized by NMR spectroscopic experiments. All compounds were assessed for their neuroprotective effects on PC12 cell lines induced by H
Identifiants
pubmed: 35218144
doi: 10.1002/cbdv.202100962
doi:
Substances chimiques
Lignans
0
Neuroprotective Agents
0
Sesquiterpenes
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202100962Subventions
Organisme : Heilongjiang University of Chinese medicine Founds
ID : 2018bs03
Organisme : Heilongjiang University of Chinese medicine Founds
ID : 2018pt01
Organisme : Heilongjiang Touyan Innovation Team Program
Organisme : National Key Research and Development Project
ID : 2018YFC1707100
Informations de copyright
© 2022 Wiley-VHCA AG, Zurich, Switzerland.
Références
S. Y. Yang, C. H. Yuan, ‘Schisandra chinensis: A comprehensive review on its phytochemicals and biological activities’, Arab. J. Chem. 2021, 14, 103310.
H. M. Kim, B. Ryu, J. S. Lee, J. H. Choi, D. S. Jang, ‘Schisandrosides A-D, Dibenzocyclooctadiene Lignan Glucosides from the Roots of Schisandra chinensis’, Chem. Pharm. Bull. 2015, 63, 746-751.
Q. Y. Song, K. Gao, Z. B. Nan, ‘Highly oxygenated triterpenoids from the roots of Schisandra chinensis and their anti-inflammatory activities’, J. Asian Nat. Prod. Res. 2015, 18, 189-194.
N. Tanaka, S. Amuti, S. Takahashi, D. Tsuji, K. Itoh, Y. Kashiwada, ‘Studies on non-medicinal parts of plant materials: Triterpenes from the roots of Schisandra chinensis’, Fitoterapia 2021, 152, 104939.
M. Li, X. L. Wang, X. K. Zheng, J. C. Wang, W. Zhao, K. Song, X. Zhao, Y. L. Zhang, H. X. Kuang, W. S. Feng, ‘A New Ionone Glycoside and Three New Rhemaneolignans from the Roots of Rehmannia glutinosa’, Molecules 2015, 20, 15192-15201.
Y. D. Yang, Z. X. Hu, Z. W. Luo, Y. B. Xue, G. M. Yao, Y. Y. Wang, Y. H. Zhang, ‘A New Sesquilignan Glucoside from Uraria sinensis’, Molecules 2014, 19, 1178-1188.
L. Cao, N. Shehla, S. Tasneem, M. R. Cao, W. B. Sheng, Y. Q. Jian, B. Li, C. Y. Peng M I Choudhary, A. U. Rahman, D. F. Liao, W. Wang, ‘New Cadinane Sesquiterpenes from the Stems of Kadsura heteroclita’, Molecules 2019, 24, 1664.
Y. G. Xie, S. L. Zhu, Y. Y. Huang, Y. G. Guo, G. J. Wu, I. Muhammad, S. K. Yan, H. Z. Jin, W. D. Zhang, ‘Chemical constituents from the branches of Alangium barbatum and their anti-inflammatory activities’, Phytochem. Lett. 2018, 28, 64-68.
M. Salmoun, J. C. Braekman, Y. Ranarivelo, R. Rasamoelisendra, D. Ralambomanana, J. Dewelle, F. Darro, R. Kiss, ‘New calamenene sesquiterpenes from Tarenna madagascariensis’, Nat. Prod. Res. 2007, 21, 111-120.
J. T. Bai, Y. Liu, Y. P. Sun, G. Z. Liu, X. M. Li, S. Y. Wang, A. M. Algradi, J. Pan, W. Guan, B. Y. Yang, H. X. Kuang, ‘Two new quinic acid derivatives from the leaves of Schisandra chinensis’, J. Asian Nat. Prod. Res. 2021, 1-6.
P. L. Wu, Y. L. Hsu, C. W. Zao, A. G. Damu, T. S. Wu, ‘Constituents of Vittaria anguste-elongata and their Biological Activities’, J. Nat. Prod. 2005, 68, 1180-1184.
M. Zhang, W. X. Liu, M. F. Zheng, Q. L. Xu, F. H. Wan, J. Wang, T. Lei, Z. Y. Zhou, J. W. Tan, ‘Bioactive Quinic Acid Derivatives from Ageratina adenophora’, Molecules 2013, 18, 14096-14104.
Y. L. Lin, C. K. Lu, Y. J. Huang, H. J. Chen, ‘Antioxidative Caffeoylquinic Acids and Flavonoids from Hemerocallis fulva Flowers’, J. Agric. Food Chem. 2011, 59, 8789-8795.
S. Hiroko, S. Yutaka, M. Yoshihiro, Y. Iitaka, ‘Studies on the chemical constituents of Lilium henryi Baker’, Chem. Pharm. Bull. 1988, 36, 2430-2446.
S. De Marino, F. Gala, F. Zollo, S. Vitalini, G. Fico, F. Visioli, M. Iorizzi, ‘Identification of Minor Secondary Metabolites from the Latex of Croton lechleri (Muell-Arg) and Evaluation of Their Antioxidant Activity’, Molecules 2008, 13, 1219-1229.
T. Zhang, J. H. Piao, L. Yuan, X. F. Li, ‘Chemical constituents of Acanthopanax senticosus and their free radical scavenging activities’, Chin. Tradit. Herb Drugs 2012, 43, 1057-1060.
Y. K. Chen, X. S. Li, G. Y. Yang, Z. Y. Chen, Q. F. Hu, M. M. Miao, ‘Phenolic compounds from Nicotiana tabacum and their biological activities’, J. Asian Nat. Prod. Res. 2012, 14, 450-456.
F. Ou Yang, Y. Liu, H. H. Xiao, H. Y. Yu, N. L. Wang, X. S. Yao, ‘Lignans from stems of Sambucus williamsii’, Chin. J. Chin. Mater. Med. 2009, 34, 1225-1227.
J. W. Zhou, J. L. Du, X. F. Hou, L. M. Zheng, D. Liu, H. L. Liu, J. Wang, J. Y. Hu, J. Q. Xu, J. C. Chen, J. B. Fang, ‘Sesquiterpenes from stems of Schisandra henryi var. henryi’, J. Tradit. Chin. Med. 2016, 41, 3049-3054.
W. X. Wang, L. Cao, J. Xiong, G. Xia, J. F. Hu, ‘Constituents from Chimonanthus praecox (wintersweet)’, Phytochem. Lett. 2011, 4, 271-274.