Direct Synthesis of Paracetamol via Site-Selective Electrochemical Ritter-type C-H Amination of Phenol.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
01 04 2022
01 04 2022
Historique:
pubmed:
22
3
2022
medline:
5
4
2022
entrez:
21
3
2022
Statut:
ppublish
Résumé
The synthesis of paracetamol still relies on multistep protocols involving the utilization of a stoichiometric amount of oxidizing/reducing or other corrosive agents. Herein we report a regioselective electrochemical Ritter-type reaction at the C(sp
Identifiants
pubmed: 35312329
doi: 10.1021/acs.orglett.2c00439
doi:
Substances chimiques
Phenols
0
Phenol
339NCG44TV
Acetaminophen
362O9ITL9D
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM