Direct Synthesis of Paracetamol via Site-Selective Electrochemical Ritter-type C-H Amination of Phenol.


Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
01 04 2022
Historique:
pubmed: 22 3 2022
medline: 5 4 2022
entrez: 21 3 2022
Statut: ppublish

Résumé

The synthesis of paracetamol still relies on multistep protocols involving the utilization of a stoichiometric amount of oxidizing/reducing or other corrosive agents. Herein we report a regioselective electrochemical Ritter-type reaction at the C(sp

Identifiants

pubmed: 35312329
doi: 10.1021/acs.orglett.2c00439
doi:

Substances chimiques

Phenols 0
Phenol 339NCG44TV
Acetaminophen 362O9ITL9D

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2310-2314

Auteurs

Irshad Maajid Taily (IM)

Department of Chemistry, Indian Institute of Technology Ropar, Lab no. 406, S. S. Bhatnagar Block, Rupnagar, Punjab 140001, India.

Debarshi Saha (D)

Department of Chemistry, Indian Institute of Technology Ropar, Lab no. 406, S. S. Bhatnagar Block, Rupnagar, Punjab 140001, India.

Prabal Banerjee (P)

Department of Chemistry, Indian Institute of Technology Ropar, Lab no. 406, S. S. Bhatnagar Block, Rupnagar, Punjab 140001, India.

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Classifications MeSH