Architecture of the NADPH oxidase family of enzymes.


Journal

Redox biology
ISSN: 2213-2317
Titre abrégé: Redox Biol
Pays: Netherlands
ID NLM: 101605639

Informations de publication

Date de publication:
06 2022
Historique:
received: 02 03 2022
revised: 16 03 2022
accepted: 16 03 2022
pubmed: 26 3 2022
medline: 11 5 2022
entrez: 25 3 2022
Statut: ppublish

Résumé

The NADPH Oxidases (NOX) catalyze the deliberate production of reactive oxygen species (ROS) and are established regulators of redox-dependent processes across diverse biological settings. Proper management of their activity is controlled through a conserved electron transfer (ET) cascade from cytosolic NADPH substrate through the plasma membrane to extracellular O

Identifiants

pubmed: 35334249
pii: S2213-2317(22)00070-2
doi: 10.1016/j.redox.2022.102298
pmc: PMC8956913
pii:
doi:

Substances chimiques

Reactive Oxygen Species 0
NADPH Oxidase 1 EC 1.6.3.-
NADPH Oxidase 4 EC 1.6.3.-
NADPH Oxidases EC 1.6.3.-

Types de publication

Journal Article Review Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102298

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL085646
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL138708
Pays : United States

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.

Auteurs

Blessing C Ogboo (BC)

Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, USA.

Uriy V Grabovyy (UV)

Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, USA.

Aniket Maini (A)

Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, USA.

Scott Scouten (S)

Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, USA.

Albert van der Vliet (A)

Department of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA.

Andrea Mattevi (A)

Department of Genetics and Microbiology, University of Pavia, Italy.

David E Heppner (DE)

Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, USA; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Electronic address: davidhep@buffalo.edu.

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Classifications MeSH