Rapid Exome and Genome Sequencing in the Intensive Care Unit.


Journal

Critical care clinics
ISSN: 1557-8232
Titre abrégé: Crit Care Clin
Pays: United States
ID NLM: 8507720

Informations de publication

Date de publication:
Apr 2022
Historique:
entrez: 4 4 2022
pubmed: 5 4 2022
medline: 6 4 2022
Statut: ppublish

Résumé

Rapid genomic sequencing has become a powerful diagnostic tool for critically ill children. Accumulated data support clinical utility. Advances in sequencing technology have improved reliability of rapid results and reduced turnaround times. Cost savings to health care institutions are not only the result of reduced sequencing charges (which have paralleled advances in sequencing technology), but also and more specifically have impact on diagnosis-specific medical management and reduced length of hospitalization. The use of genomic sequencing in critical care is still primarily limited to academic centers but will ultimately become the wider-spread standard of care for select patients.

Identifiants

pubmed: 35369941
pii: S0749-0704(21)00087-7
doi: 10.1016/j.ccc.2021.11.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

173-184

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Michael Muriello (M)

Genetics, Department of Pediatrics, Medical College of Wisconsin, 9000 W. Wisconsin Avenue, MC 716, Milwaukee, WI 53226, USA.

Donald Basel (D)

Genetics, Department of Pediatrics, Medical College of Wisconsin, 9000 W. Wisconsin Avenue, MC 716, Milwaukee, WI 53226, USA. Electronic address: dbasel@mcw.edu.

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Classifications MeSH