The Australian dingo is an early offshoot of modern breed dogs.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
22 04 2022
22 04 2022
Historique:
entrez:
22
4
2022
pubmed:
23
4
2022
medline:
27
4
2022
Statut:
ppublish
Résumé
Dogs are uniquely associated with human dispersal and bring transformational insight into the domestication process. Dingoes represent an intriguing case within canine evolution being geographically isolated for thousands of years. Here, we present a high-quality de novo assembly of a pure dingo (CanFam_DDS). We identified large chromosomal differences relative to the current dog reference (CanFam3.1) and confirmed no expanded pancreatic amylase gene as found in breed dogs. Phylogenetic analyses using variant pairwise matrices show that the dingo is distinct from five breed dogs with 100% bootstrap support when using Greenland wolf as the outgroup. Functionally, we observe differences in methylation patterns between the dingo and German shepherd dog genomes and differences in serum biochemistry and microbiome makeup. Our results suggest that distinct demographic and environmental conditions have shaped the dingo genome. In contrast, artificial human selection has likely shaped the genomes of domestic breed dogs after divergence from the dingo.
Identifiants
pubmed: 35452284
doi: 10.1126/sciadv.abm5944
pmc: PMC9032958
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
eabm5944Subventions
Organisme : NHGRI NIH HHS
ID : UM1 HG009375
Pays : United States
Références
Sci Rep. 2021 Mar 4;11(1):5245
pubmed: 33664285
PLoS One. 2010 Mar 10;5(3):e9490
pubmed: 20224823
Front Zool. 2019 Feb 13;16:2
pubmed: 30805020
Comput Struct Biotechnol J. 2019 Dec 23;18:83-92
pubmed: 32099591
Nucleic Acids Res. 2013 Jan 7;41(1):e1
pubmed: 22933715
Nucleic Acids Res. 2013 Sep;41(16):e155
pubmed: 23828043
Anim Genet. 2014 Oct;45(5):716-22
pubmed: 24975239
BMC Genomics. 2021 Mar 16;22(1):188
pubmed: 33726677
Life Sci Alliance. 2021 Jan 29;4(4):
pubmed: 33514656
Curr Zool. 2021 Mar 17;68(4):423-432
pubmed: 36090142
Wellcome Open Res. 2021 Nov 12;6:310
pubmed: 34926833
QJM. 2003 Dec;96(12):927-34
pubmed: 14631060
Bioinformatics. 2005 Nov 1;21 Suppl 3:iii3-11
pubmed: 16306389
Nat Methods. 2018 Jun;15(6):461-468
pubmed: 29713083
Mol Biol Evol. 2013 Apr;30(4):772-80
pubmed: 23329690
Science. 2017 Apr 7;356(6333):92-95
pubmed: 28336562
Front Psychol. 2017 Sep 07;8:1520
pubmed: 28936190
Integr Comp Biol. 2020 Dec 16;60(6):1558-1566
pubmed: 32835371
Cell Syst. 2016 Jul;3(1):95-8
pubmed: 27467249
Acta Physiol Pol. 1964 Jan-Feb;15:137-48
pubmed: 14196030
BMC Vet Res. 2021 Mar 6;17(1):112
pubmed: 33676490
PLoS One. 2013 Apr 22;8(4):e61217
pubmed: 23630581
J Anim Physiol Anim Nutr (Berl). 2018 Apr;102(2):568-575
pubmed: 29024089
Mamm Genome. 2019 Oct;30(9-10):289-300
pubmed: 31414176
Cell Syst. 2018 Feb 28;6(2):256-258.e1
pubmed: 29428417
Anaerobe. 2012 Feb;18(1):55-61
pubmed: 21979490
Bioinformatics. 2014 Aug 1;30(15):2114-20
pubmed: 24695404
PeerJ. 2019 Dec 13;7:e8206
pubmed: 31844586
Cell Rep. 2017 Apr 25;19(4):697-708
pubmed: 28445722
Front Physiol. 2019 Mar 14;10:185
pubmed: 30923502
Environ Microbiome. 2020 May 18;15(1):11
pubmed: 33902725
Hepatology. 1992 Aug;16(2):358-64
pubmed: 1639344
R Soc Open Sci. 2016 Nov 9;3(11):160449
pubmed: 28018628
Heredity (Edinb). 2012 Jan;108(1):17-27
pubmed: 22086079
Genome Biol. 2020 Sep 14;21(1):245
pubmed: 32928274
J Biochem. 2018 Apr 1;163(4):253-263
pubmed: 29186467
Nature. 2005 Dec 8;438(7069):803-19
pubmed: 16341006
PLoS Genet. 2018 Nov 12;14(11):e1007745
pubmed: 30419012
Am J Physiol Gastrointest Liver Physiol. 2017 Jun 1;312(6):G550-G558
pubmed: 28360029
Cytogenet Genome Res. 2019;159(2):88-96
pubmed: 31593945
Bioinformatics. 2010 Oct 1;26(19):2460-1
pubmed: 20709691
Methods Mol Biol. 2019;1962:161-177
pubmed: 31020559
Heredity (Edinb). 2016 Nov;117(5):301-306
pubmed: 27406651
Bioinformatics. 2015 Oct 1;31(19):3210-2
pubmed: 26059717
Nature. 2013 Mar 21;495(7441):360-4
pubmed: 23354050
Nucleic Acids Res. 2013 Jan;41(Database issue):D590-6
pubmed: 23193283
BMC Bioinformatics. 2018 Nov 29;19(1):460
pubmed: 30497373
Bioinformatics. 2017 Feb 15;33(4):574-576
pubmed: 27797770
PLoS Biol. 2017 Apr 25;15(4):e2000862
pubmed: 28441450
PLoS One. 2017 May 11;12(5):e0176715
pubmed: 28493883
Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24369-24376
pubmed: 32868416
Genome Res. 2017 May;27(5):722-736
pubmed: 28298431
Microb Ecol Health Dis. 2015 May 29;26:27663
pubmed: 26028277
Bioinformatics. 2016 Nov 15;32(22):3507-3509
pubmed: 27466624
Mol Ecol. 2015 Nov;24(22):5643-56
pubmed: 26514639
Gastroenterol Res Pract. 2015;2015:717431
pubmed: 25821461
Behav Ecol. 2013 Jan;24(1):293-304
pubmed: 23243377
Br J Nutr. 2015 Jan;113 Suppl:S40-54
pubmed: 25415597
Anim Cogn. 2019 Nov;22(6):1073-1083
pubmed: 31385068
Gigascience. 2020 Jan 1;9(1):
pubmed: 31895413
Nat Protoc. 2015 Mar;10(3):475-83
pubmed: 25692984
Nat Commun. 2020 Feb 3;11(1):671
pubmed: 32015346
J Biol Chem. 2001 Jul 13;276(28):25697-704
pubmed: 11333265
J Ethnobiol Ethnomed. 2009 Jan 12;5:2
pubmed: 19138420
Gut Microbes. 2016;7(1):22-39
pubmed: 26939849
Anim Genet. 2019 Dec;50(6):695-704
pubmed: 31486122
Cell Metab. 2014 Nov 4;20(5):779-786
pubmed: 25156449
Nature. 2015 Dec 24;528(7583):499-503
pubmed: 26595274
PLoS Comput Biol. 2017 Feb 21;13(2):e1005404
pubmed: 28222096
Cell Host Microbe. 2019 Apr 10;25(4):553-564.e7
pubmed: 30974084
BMC Vet Res. 2017 Nov 25;13(1):354
pubmed: 29178874
PLoS Comput Biol. 2018 Jan 26;14(1):e1005944
pubmed: 29373581
J Biol Chem. 1997 Feb 21;272(8):4864-8
pubmed: 9030544
Gigascience. 2020 Apr 1;9(4):
pubmed: 32236524
PLoS One. 2012;7(11):e47768
pubmed: 23185243
PLoS One. 2014 Nov 19;9(11):e112963
pubmed: 25409509
PLoS One. 2020 Oct 29;15(10):e0240787
pubmed: 33119634
Bioinformatics. 2009 Aug 15;25(16):2078-9
pubmed: 19505943
BMC Bioinformatics. 2018 Jan 30;19(1):26
pubmed: 29382321
PLoS Genet. 2014 Jan;10(1):e1004016
pubmed: 24453982
Bioinformatics. 2018 Sep 15;34(18):3094-3100
pubmed: 29750242
Nature. 2015 Jan 15;517(7534):321-6
pubmed: 25592537
Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):
pubmed: 33836575