Analysis of the polymerized impurities in cefmetazole sodium based on novel separation principle by liquid chromatography tandem ion trap/time-of-flight mass spectrometry.

Cefmetazole Chromatography, High Pressure Liquid / methods Chromatography, Liquid / methods Drug Contamination Mass Spectrometry
Cefmetazole sodium HPSEC LC-IT-TOF MS Polymerized impurity RP-HPLC

Journal

Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336

Informations de publication

Date de publication:
05 Jun 2022
Historique:
received: 03 11 2021
revised: 17 04 2022
accepted: 20 04 2022
pubmed: 29 4 2022
medline: 12 5 2022
entrez: 28 4 2022
Statut: ppublish

Résumé

To effectively control the polymerized impurities in cefmetazole sodium, novel high performance gel filtration chromatography (HPSEC) with TSK-gel G2000SWxl column and RP-HPLC method with C

Identifiants

DOI: 10.1016/j.jpba.2022.114790 PMID: 35483231
pubmed: 35483231
pii: S0731-7085(22)00211-4
doi: 10.1016/j.jpba.2022.114790
pii:
doi:

Substances chimiques

Cefmetazole 3J962UJT8H

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

114790

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Fan Wang (F)

Zhejiang University, Hangzhou 310058, China; Zhejiang Institute for Food and Drug Control, Key Laboratory for Core Technology of Generic Drug Evaluation National Medical Product Administration & Key laboratory of drug contacting materials quality control of zhejiang province, Hangzhou, 310052, China.

Xiaojuan Ren (X)

Zhejiang University of Technology, Hangzhou 310014, China.

Bingqi Zhu (B)

Zhejiang Chinese Medical University, Hangzhou 310053, China.

Fengmei Zhang (F)

Zhejiang Institute for Food and Drug Control, Key Laboratory for Core Technology of Generic Drug Evaluation National Medical Product Administration & Key laboratory of drug contacting materials quality control of zhejiang province, Hangzhou, 310052, China.

Jiarui Gao (J)

Zhejiang University of Technology, Hangzhou 310014, China.

Liya Hong (L)

Zhejiang Institute for Food and Drug Control, Key Laboratory for Core Technology of Generic Drug Evaluation National Medical Product Administration & Key laboratory of drug contacting materials quality control of zhejiang province, Hangzhou, 310052, China. Electronic address: lyhong987@163.com.

Jian Wang (J)

Zhejiang Institute for Food and Drug Control, Key Laboratory for Core Technology of Generic Drug Evaluation National Medical Product Administration & Key laboratory of drug contacting materials quality control of zhejiang province, Hangzhou, 310052, China; Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: wangjianhw2000@163.com.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Céphalosporines › Céfamycines › Cefmétazole › Analysis of the polymerized impurities in...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › Chromatographie en phase liquide à haute performance › Analysis of the polymerized impurities in...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Chromatographie › Chromatographie en phase liquide › Analysis of the polymerized impurities in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Contamination de médicament › Analysis of the polymerized impurities in...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Analysis of the polymerized impurities in...