Cryo-EM structures of the β

Adrenergic beta-3 Receptor Agonists / pharmacology Aniline Compounds Benzoates Biphenyl Compounds Cryoelectron Microscopy Diabetes Mellitus, Type 2 / drug therapy Humans Isoproterenol / pharmacology Receptors, Adrenergic, beta-3 / metabolism
GPCR Ligand recognition adrenergic receptor cryo-EM

Journal

Biochemical and biophysical research communications
ISSN: 1090-2104
Titre abrégé: Biochem Biophys Res Commun
Pays: United States
ID NLM: 0372516

Informations de publication

Date de publication:
30 06 2022
Historique:
received: 05 04 2022
revised: 12 04 2022
accepted: 14 04 2022
pubmed: 1 5 2022
medline: 26 5 2022
entrez: 30 4 2022
Statut: ppublish

Résumé

The β

Identifiants

DOI: 10.1016/j.bbrc.2022.04.065 PMID: 35489202
pubmed: 35489202
pii: S0006-291X(22)00594-0
doi: 10.1016/j.bbrc.2022.04.065
pii:
doi:

Substances chimiques

Adrenergic beta-3 Receptor Agonists 0
Aniline Compounds 0
Benzoates 0
Biphenyl Compounds 0
Receptors, Adrenergic, beta-3 0
solabegron 55P6YH9O6N
Isoproterenol L628TT009W

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

158-164

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest O.N. is a co-founder and an external director of Curreio, Inc.

Auteurs

Ikko Nureki (I)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Kazuhiro Kobayashi (K)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Tatsuki Tanaka (T)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Kanae Demura (K)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Asuka Inoue (A)

Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan. Electronic address: iaska@tohoku.ac.jp.

Wataru Shihoya (W)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address: wtrshh9@gmail.com.

Osamu Nureki (O)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address: nureki@bs.s.u-tokyo.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents adrénergiques › Agonistes adrénergiques › Agonistes bêta-adrénergiques › Agonistes des récepteurs bêta-3 adrénergiques › Cryo-EM structures of the β
questionsmedicales.fr › Composés chimiques organiques › Amines › Dérivés de l'aniline › Cryo-EM structures of the β
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Benzoates › Cryo-EM structures of the β
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Dérivés du biphényle › Cryo-EM structures of the β
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Cryomicroscopie électronique › Cryo-EM structures of the β
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › Cryo-EM structures of the β
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cryo-EM structures of the β
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Catéchols › Catécholamines › Isoprénaline › Cryo-EM structures of the β
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs catécholaminergiques › Récepteurs adrénergiques › Récepteurs bêta-adrénergiques › Récepteurs bêta-3 adrénergiques › Cryo-EM structures of the β