Osamu Nureki

Affiliations
  • Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp.
ORCID: http://orcid.org/0000-0003-1813-7008

Publications (85)

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.

Nature structural & molecular biology
Avec: Yongchan Lee , Pattama Wiriyasermkul , Chunhuan Jin , Lili Quan , Ryuichi Ohgaki , Suguru Okuda , Tsukasa Kusakizako , Tomohiro Nishizawa , Kazumasa Oda , Ryuichiro Ishitani , Takeshi Yokoyama , Takanori Nakane , Mikako Shirouzu , Hitoshi Endou , Shushi Nagamori , Yoshikatsu Kanai , Osamu Nureki

Author Correction: Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.

Nature
Avec: Yoshiki Tanaka , Christopher J Hipolito , Andrés D Maturana , Koichi Ito , Teruo Kuroda , Takashi Higuchi , Takayuki Katoh , Hideaki E Kato , Motoyuki Hattori , Kaoru Kumazaki , Tomoya Tsukazaki , Ryuichiro Ishitani , Hiroaki Suga , Osamu Nureki

The bacterial protein YidC accelerates MPIase-dependent integration of membrane proteins.

The Journal of biological chemistry
Avec: Masaru Sasaki , Hanako Nishikawa , Sonomi Suzuki , Michael Moser , Maria Huber , Katsuhiro Sawasato , Hideaki T Matsubayashi , Kaoru Kumazaki , Tomoya Tsukazaki , Yutetsu Kuruma , Osamu Nureki , Takuya Ueda , Ken-Ichi Nishiyama

Structural basis for oligomerization of the prokaryotic peptide transporter PepT

Acta crystallographica. Section F, Structural biology communications
Avec: Reina Nagamura , Masahiro Fukuda , Akihiro Kawamoto , Kyoko Matoba , Naoshi Dohmae , Ryuichiro Ishitani , Junichi Takagi , Osamu Nureki

Structural basis of gating modulation of Kv4 channel complexes.

Nature
Avec: Yoshiaki Kise , Go Kasuya , Hiroyuki H Okamoto , Daichi Yamanouchi , Kan Kobayashi , Tsukasa Kusakizako , Tomohiro Nishizawa , Koichi Nakajo , Osamu Nureki

Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na

The Journal of biological chemistry
Avec: Steven Castellano , Derek P Claxton , Emel Ficici , Tsukasa Kusakizako , Robyn Stix , Wenchang Zhou , Osamu Nureki , Hassane S Mchaourab , José D Faraldo-Gómez

Structural insights into the mechanism of rhodopsin phosphodiesterase.

Nature communications
Avec: Tatsuya Ikuta , Wataru Shihoya , Masahiro Sugiura , Kazuho Yoshida , Masahito Watari , Takaya Tokano , Keitaro Yamashita , Kota Katayama , Satoshi P Tsunoda , Takayuki Uchihashi , Hideki Kandori , Osamu Nureki

B/N-Doped

Journal of the American Chemical Society
Avec: Hua Lu , Takayuki Nakamuro , Keitaro Yamashita , Haruaki Yanagisawa , Osamu Nureki , Masahide Kikkawa , Han Gao , Jiangwei Tian , Rui Shang , Eiichi Nakamura

Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na

The Journal of biological chemistry
Avec: Steven Castellano , Derek P Claxton , Emel Ficici , Tsukasa Kusakizako , Robyn Stix , Wenchang Zhou , Osamu Nureki , Hassane S Mchaourab , José D Faraldo-Gómez

Precise CAG repeat contraction in a Huntington's Disease mouse model is enabled by gene editing with SpCas9-NG.

Communications biology
Avec: Seiya Oura , Taichi Noda , Naoko Morimura , Seiji Hitoshi , Hiroshi Nishimasu , Yoshitaka Nagai , Osamu Nureki , Masahito Ikawa

Cryo-EM structures of the β

Biochemical and biophysical research communications
Avec: Ikko Nureki , Kazuhiro Kobayashi , Tatsuki Tanaka , Kanae Demura , Asuka Inoue , Wataru Shihoya , Osamu Nureki

Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility.

Nature communications
Avec: Haon Futamata , Masahiro Fukuda , Rie Umeda , Keitaro Yamashita , Atsuhiro Tomita , Satoe Takahashi , Takafumi Shikakura , Shigehiko Hayashi , Tsukasa Kusakizako , Tomohiro Nishizawa , Kazuaki Homma , Osamu Nureki

Structure and engineering of the minimal type VI CRISPR-Cas13bt3.

Molecular cell
Avec: Ryoya Nakagawa , Soumya Kannan , Han Altae-Tran , Satoru N Takeda , Atsuhiro Tomita , Hisato Hirano , Tsukasa Kusakizako , Tomohiro Nishizawa , Keitaro Yamashita , Feng Zhang , Hiroshi Nishimasu , Osamu Nureki

Genome editing in rice mediated by miniature size Cas nuclease SpCas12f.

Frontiers in genome editing
Avec: Satoru Sukegawa , Osamu Nureki , Seiichi Toki , Hiroaki Saika

Cryo-EM advances in GPCR structure determination.

Journal of biochemistry
Avec: Wataru Shihoya , Aika Iwama , Fumiya K Sano , Osamu Nureki

Melatonin receptor structure and signaling.

Journal of pineal research
Avec: Hiroyuki H Okamoto , Erika Cecon , Osamu Nureki , Silvia Rivara , Ralf Jockers

Cryo-EM structure of I domain-containing integrin αEβ7.

Biochemical and biophysical research communications
Avec: Hiroaki Akasaka , Dan Sato , Wataru Shihoya , Osamu Nureki , Yoshiaki Kise

Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.

Science (New York, N.Y.)
Avec: Masahiro Hiraizumi , Keitaro Yamashita , Tomohiro Nishizawa , Osamu Nureki

Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9.

Nature communications
Avec: Seiichi Hirano , Omar O Abudayyeh , Jonathan S Gootenberg , Takuro Horii , Ryuichiro Ishitani , Izuho Hatada , Feng Zhang , Hiroshi Nishimasu , Osamu Nureki

The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism.

Nature structural & molecular biology
Avec: Hiroto Shimada , Tsukasa Kusakizako , T H Dung Nguyen , Tomohiro Nishizawa , Tomoya Hino , Makoto Tominaga , Osamu Nureki

Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.

Communications biology
Avec: Ryoki Nakamura , Tomohiro Numata , Go Kasuya , Takeshi Yokoyama , Tomohiro Nishizawa , Tsukasa Kusakizako , Takafumi Kato , Tatsuya Hagino , Naoshi Dohmae , Masato Inoue , Kengo Watanabe , Hidenori Ichijo , Masahide Kikkawa , Mikako Shirouzu , Thomas J Jentsch , Ryuichiro Ishitani , Yasunobu Okada , Osamu Nureki

Generation of novel Il2rg-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9.

Experimental animals
Avec: Suvd Byambaa , Hideki Uosaki , Hiromasa Hara , Yasumitsu Nagao , Tomoyuki Abe , Hiroaki Shibata , Osamu Nureki , Tsukasa Ohmori , Yutaka Hanazono

Amplification-free RNA detection with CRISPR-Cas13.

Communications biology
Avec: Hajime Shinoda , Yuya Taguchi , Ryoya Nakagawa , Asami Makino , Sae Okazaki , Masahiro Nakano , Yukiko Muramoto , Chiharu Takahashi , Ikuko Takahashi , Jun Ando , Takeshi Noda , Osamu Nureki , Hiroshi Nishimasu , Rikiya Watanabe

The structure of MgtE in the absence of magnesium provides new insights into channel gating.

PLoS biology
Avec: Fei Jin , Minxuan Sun , Takashi Fujii , Yurika Yamada , Jin Wang , Andrés D Maturana , Miki Wada , Shichen Su , Jinbiao Ma , Hironori Takeda , Tsukasa Kusakizako , Atsuhiro Tomita , Yoshiko Nakada-Nakura , Kehong Liu , Tomoko Uemura , Yayoi Nomura , Norimichi Nomura , Koichi Ito , Osamu Nureki , Keiichi Namba , So Iwata , Ye Yu , Motoyuki Hattori

Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Akimitsu Higuchi , Wataru Shihoya , Masae Konno , Tatsuya Ikuta , Hideki Kandori , Keiichi Inoue , Osamu Nureki

Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine.

Cell
Avec: Koichiro E Kishi , Yoon Seok Kim , Masahiro Fukuda , Masatoshi Inoue , Tsukasa Kusakizako , Peter Y Wang , Charu Ramakrishnan , Eamon F X Byrne , Elina Thadhani , Joseph M Paggi , Toshiki E Matsui , Keitaro Yamashita , Takashi Nagata , Masae Konno , Sean Quirin , Maisie Lo , Tyler Benster , Tomoko Uemura , Kehong Liu , Mikihiro Shibata , Norimichi Nomura , So Iwata , Osamu Nureki , Ron O Dror , Keiichi Inoue , Karl Deisseroth , Hideaki E Kato

Lateral access mechanism of LPA receptor probed by molecular dynamics simulation.

PloS one
Avec: Rieko Suenaga , Mizuki Takemoto , Asuka Inoue , Ryuichiro Ishitani , Osamu Nureki

Pharmacophore-guided Virtual Screening to Identify New β

Molecular informatics
Avec: Navista Sri Octa Ujiantari , Seungmin Ham , Chisae Nagiri , Wataru Shihoya , Osamu Nureki , Dana Sabine Hutchinson , Daniela Schuster

Recent Advances in the Structural Biology of the Volume-Regulated Anion Channel LRRC8.

Frontiers in pharmacology
Avec: Go Kasuya , Osamu Nureki

Mechanistic insights into intramembrane proteolysis by

Science advances
Avec: Yuki Imaizumi , Kazunori Takanuki , Takuya Miyake , Mizuki Takemoto , Kunio Hirata , Mika Hirose , Rika Oi , Tatsuya Kobayashi , Kenichi Miyoshi , Rie Aruga , Tatsuhiko Yokoyama , Shizuka Katagiri , Hiroaki Matsuura , Kenji Iwasaki , Takayuki Kato , Mika K Kaneko , Yukinari Kato , Michiko Tajiri , Satoko Akashi , Osamu Nureki , Yohei Hizukuri , Yoshinori Akiyama , Terukazu Nogi

Class B1 GPCR activation by an intracellular agonist.

Nature
Avec: Kazuhiro Kobayashi , Kouki Kawakami , Tsukasa Kusakizako , Atsuhiro Tomita , Michihiro Nishimura , Kazuhiro Sawada , Hiroyuki H Okamoto , Suzune Hiratsuka , Gaku Nakamura , Riku Kuwabara , Hiroshi Noda , Hiroyasu Muramatsu , Masaru Shimizu , Tomohiko Taguchi , Asuka Inoue , Takeshi Murata , Osamu Nureki

SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine.

Cell reports
Avec: Setsuko Mise-Omata , Makoto Ando , Tanakorn Srirat , Kensuke Nakagawara , Taeko Hayakawa , Mana Iizuka-Koga , Hiroshi Nishimasu , Osamu Nureki , Minako Ito , Akihiko Yoshimura

Genome editing of patient-derived iPSCs identifies a deep intronic variant causing aberrant splicing in hemophilia A.

Blood advances
Avec: Takafumi Hiramoto , Hiroshi Inaba , Nemekhbayar Baatartsogt , Yuji Kashiwakura , Morisada Hayakawa , Nobuhiko Kamoshita , Hiroshi Nishimasu , Osamu Nureki , Ei Kinai , Tsukasa Ohmori

Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury.

Nature communications
Avec: Airi Jo-Watanabe , Toshiki Inaba , Takahiro Osada , Ryota Hashimoto , Tomohiro Nishizawa , Toshiaki Okuno , Sayoko Ihara , Kazushige Touhara , Nobutaka Hattori , Masatsugu Oh-Hora , Osamu Nureki , Takehiko Yokomizo

The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.

Molecular cell
Avec: Tatsuki Tanaka , Shoko Hososhima , Yo Yamashita , Teppei Sugimoto , Toshiki Nakamura , Shunta Shigemura , Wataru Iida , Fumiya K Sano , Kazumasa Oda , Takayuki Uchihashi , Kota Katayama , Yuji Furutani , Satoshi P Tsunoda , Wataru Shihoya , Hideki Kandori , Osamu Nureki

PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics.

Nature communications
Avec: Sundaram Acharya , Asgar Hussain Ansari , Prosad Kumar Das , Seiichi Hirano , Meghali Aich , Riya Rauthan , Sudipta Mahato , Savitri Maddileti , Sajal Sarkar , Manoj Kumar , Rhythm Phutela , Sneha Gulati , Abdul Rahman , Arushi Goel , C Afzal , Deepanjan Paul , Trupti Agrawal , Vinay Kumar Pulimamidi , Subhadra Jalali , Hiroshi Nishimasu , Indumathi Mariappan , Osamu Nureki , Souvik Maiti , Debojyoti Chakraborty

Base editors for simultaneous introduction of C-to-T and A-to-G mutations.

Nature biotechnology
Avec: Rina C Sakata , Soh Ishiguro , Hideto Mori , Mamoru Tanaka , Kenji Tatsuno , Hiroki Ueda , Shogo Yamamoto , Motoaki Seki , Nanami Masuyama , Keiji Nishida , Hiroshi Nishimasu , Kazuharu Arakawa , Akihiko Kondo , Osamu Nureki , Masaru Tomita , Hiroyuki Aburatani , Nozomu Yachie

Publisher Correction: Base editors for simultaneous introduction of C-to-T and A-to-G mutations.

Nature biotechnology
Avec: Rina C Sakata , Soh Ishiguro , Hideto Mori , Mamoru Tanaka , Kenji Tatsuno , Hiroki Ueda , Shogo Yamamoto , Motoaki Seki , Nanami Masuyama , Keiji Nishida , Hiroshi Nishimasu , Kazuharu Arakawa , Akihiko Kondo , Osamu Nureki , Masaru Tomita , Hiroyuki Aburatani , Nozomu Yachie

Crystal structure of Drosophila Piwi.

Nature communications
Avec: Sonomi Yamaguchi , Akira Oe , Kazumichi M Nishida , Keitaro Yamashita , Asako Kajiya , Seiichi Hirano , Naoki Matsumoto , Naoshi Dohmae , Ryuichiro Ishitani , Kuniaki Saito , Haruhiko Siomi , Hiroshi Nishimasu , Mikiko C Siomi , Osamu Nureki

Crystal structure of heliorhodopsin.

Nature
Avec: Wataru Shihoya , Keiichi Inoue , Manish Singh , Masae Konno , Shoko Hososhima , Keitaro Yamashita , Kento Ikeda , Akimitsu Higuchi , Tamaki Izume , Sae Okazaki , Masanori Hashimoto , Ritsu Mizutori , Sahoko Tomida , Yumeka Yamauchi , Rei Abe-Yoshizumi , Kota Katayama , Satoshi P Tsunoda , Mikihiro Shibata , Yuji Furutani , Alina Pushkarev , Oded Béjà , Takayuki Uchihashi , Hideki Kandori , Osamu Nureki

Ultrafast Dynamics of Heliorhodopsins.

The journal of physical chemistry. B
Avec: Shinya Tahara , Manish Singh , Hikaru Kuramochi , Wataru Shihoya , Keiichi Inoue , Osamu Nureki , Oded Béjà , Yasuhisa Mizutani , Hideki Kandori , Tahei Tahara

Structural Basis of H

Structure (London, England : 1993)
Avec: Tsukasa Kusakizako , Derek P Claxton , Yoshiki Tanaka , Andrés D Maturana , Teruo Kuroda , Ryuichiro Ishitani , Hassane S Mchaourab , Osamu Nureki

Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin.

eLife
Avec: Kazumasa Oda , Takashi Nomura , Takanori Nakane , Keitaro Yamashita , Keiichi Inoue , Shota Ito , Johannes Vierock , Kunio Hirata , Andrés D Maturana , Kota Katayama , Tatsuya Ikuta , Itsuki Ishigami , Tamaki Izume , Rie Umeda , Ryuun Eguma , Satomi Oishi , Go Kasuya , Takafumi Kato , Tsukasa Kusakizako , Wataru Shihoya , Hiroto Shimada , Tomoyuki Takatsuji , Mizuki Takemoto , Reiya Taniguchi , Atsuhiro Tomita , Ryoki Nakamura , Masahiro Fukuda , Hirotake Miyauchi , Yongchan Lee , Eriko Nango , Rie Tanaka , Tomoyuki Tanaka , Michihiro Sugahara , Tetsunari Kimura , Tatsuro Shimamura , Takaaki Fujiwara , Yasuaki Yamanaka , Shigeki Owada , Yasumasa Joti , Kensuke Tono , Ryuichiro Ishitani , Shigehiko Hayashi , Hideki Kandori , Peter Hegemann , So Iwata , Minoru Kubo , Tomohiro Nishizawa , Osamu Nureki

Alternating Heterochiral Supramolecular Copolymerization.

Journal of the American Chemical Society
Avec: Michihisa Ueda , Tsubasa Aoki , Takayoshi Akiyama , Takayuki Nakamuro , Keitaro Yamashita , Haruaki Yanagisawa , Osamu Nureki , Masahide Kikkawa , Eiichi Nakamura , Takuzo Aida , Yoshimitsu Itoh

Taste transduction and channel synapses in taste buds.

Pflugers Archiv : European journal of physiology
Avec: Akiyuki Taruno , Kengo Nomura , Tsukasa Kusakizako , Zhongming Ma , Osamu Nureki , J Kevin Foskett

Molecular mechanisms of building blocks of life towards medicinal applications.

The Keio journal of medicine
Avec: Osamu Nureki

Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis.

Communications biology
Avec: Hajime Shinoda , Tatsuya Iida , Asami Makino , Mami Yoshimura , Junichiro Ishikawa , Jun Ando , Kazue Murai , Katsumi Sugiyama , Yukiko Muramoto , Masahiro Nakano , Kotaro Kiga , Longzhu Cui , Osamu Nureki , Hiroaki Takeuchi , Takeshi Noda , Hiroshi Nishimasu , Rikiya Watanabe

Cell-Free Synthesis of Human Endothelin Receptors and Its Application to Ribosome Display.

Analytical chemistry
Avec: Hiroki Nakai , Kinuka Isshiki , Masato Hattori , Hiromasa Maehira , Tatsumi Yamaguchi , Keiko Masuda , Yoshihiro Shimizu , Takayoshi Watanabe , Takahiro Hohsaka , Wataru Shihoya , Osamu Nureki , Yasuhiko Kato , Hajime Watanabe , Tomoaki Matsuura

Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2.

Nature communications
Avec: Takafumi Kato , Tsukasa Kusakizako , Chunhuan Jin , Xinyu Zhou , Ryuichi Ohgaki , LiLi Quan , Minhui Xu , Suguru Okuda , Kan Kobayashi , Keitaro Yamashita , Tomohiro Nishizawa , Yoshikatsu Kanai , Osamu Nureki

Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.

Nature
Avec: Sonomi Yamaguchi , Masahiro Naganuma , Tomohiro Nishizawa , Tsukasa Kusakizako , Yukihide Tomari , Hiroshi Nishimasu , Osamu Nureki

Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.

Nature structural & molecular biology
Avec: Masahiro Hiraizumi , Tomoya Akashi , Kouta Murasaki , Hiroyuki Kishida , Taichi Kumanomidou , Nao Torimoto , Osamu Nureki , Ikuko Miyaguchi

Dual allosteric modulation of voltage and calcium sensitivities of the Slo1-LRRC channel complex.

Molecular cell
Avec: Daichi Yamanouchi , Go Kasuya , Koichi Nakajo , Yoshiaki Kise , Osamu Nureki

PAM-flexible Cas9-mediated base editing of a hemophilia B mutation in induced pluripotent stem cells.

Communications medicine
Avec: Takafumi Hiramoto , Yuji Kashiwakura , Morisada Hayakawa , Nemekhbayar Baatartsogt , Nobuhiko Kamoshita , Tomoyuki Abe , Hiroshi Inaba , Hiroshi Nishimasu , Hideki Uosaki , Yutaka Hanazono , Osamu Nureki , Tsukasa Ohmori

Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport.

Nature communications
Avec: Satoshi Watanabe , Yoshiaki Kise , Kento Yonezawa , Mariko Inoue , Nobutaka Shimizu , Osamu Nureki , Kenji Inaba

Structure of the human Bre1 complex bound to the nucleosome.

Nature communications
Avec: Shuhei Onishi , Kotone Uchiyama , Ko Sato , Chikako Okada , Shunsuke Kobayashi , Keisuke Hamada , Tomohiro Nishizawa , Osamu Nureki , Kazuhiro Ogata , Toru Sengoku

Structural basis for lysophosphatidylserine recognition by GPR34.

Nature communications
Avec: Tamaki Izume , Ryo Kawahara , Akiharu Uwamizu , Luying Chen , Shun Yaginuma , Jumpei Omi , Hiroki Kawana , Fengjue Hou , Fumiya K Sano , Tatsuki Tanaka , Kazuhiro Kobayashi , Hiroyuki H Okamoto , Yoshiaki Kise , Tomohiko Ohwada , Junken Aoki , Wataru Shihoya , Osamu Nureki

Dimeric transport mechanism of human vitamin C transporter SVCT1.

Nature communications
Avec: Takaaki A Kobayashi , Hiroto Shimada , Fumiya K Sano , Yuzuru Itoh , Sawako Enoki , Yasushi Okada , Tsukasa Kusakizako , Osamu Nureki

Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.

Nature communications
Avec: Aika Iwama , Ryoji Kise , Hiroaki Akasaka , Fumiya K Sano , Hidetaka S Oshima , Asuka Inoue , Wataru Shihoya , Osamu Nureki

Exploring RNA-guided DNA scissors in eukaryotes: Are Fanzors counterparts of CRISPR-Cas12s?

Cell
Avec: Satoshi N Omura , Osamu Nureki

Structural biology of the multidrug and toxic compound extrusion superfamily transporters.

Biochimica et biophysica acta. Biomembranes
Avec: Tsukasa Kusakizako , Hirotake Miyauchi , Ryuichiro Ishitani , Osamu Nureki

TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels.

Neuron
Avec: Yanyan Jia , Yimeng Zhao , Tsukasa Kusakizako , Yao Wang , Chengfang Pan , Yuwei Zhang , Osamu Nureki , Motoyuki Hattori , Zhiqiang Yan

Crystal structure of human endothelin ET

Biochemical and biophysical research communications
Avec: Tamaki Izume , Hirotake Miyauchi , Wataru Shihoya , Osamu Nureki

Crystal structure of human endothelin ET

Communications biology
Avec: Chisae Nagiri , Wataru Shihoya , Asuka Inoue , Francois Marie Ngako Kadji , Junken Aoki , Osamu Nureki

Crystallization of the human tetraspanin protein CD9.

Acta crystallographica. Section F, Structural biology communications
Avec: Rie Umeda , Tomohiro Nishizawa , Osamu Nureki

Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM.

Cell reports
Avec: Hanayo Nakanishi , Tomohiro Nishizawa , Katsumori Segawa , Osamu Nureki , Yoshinori Fujiyoshi , Shigekazu Nagata , Kazuhiro Abe

Consensus mutagenesis approach improves the thermal stability of system x

Protein science : a publication of the Protein Society
Avec: Kazumasa Oda , Yongchan Lee , Pattama Wiriyasermkul , Yoko Tanaka , Mizuki Takemoto , Keitaro Yamashita , Shushi Nagamori , Tomohiro Nishizawa , Osamu Nureki

Structural basis for unique color tuning mechanism in heliorhodopsin.

Biochemical and biophysical research communications
Avec: Tatsuki Tanaka , Manish Singh , Wataru Shihoya , Keitaro Yamashita , Hideki Kandori , Osamu Nureki

Structure of the miniature type V-F CRISPR-Cas effector enzyme.

Molecular cell
Avec: Satoru N Takeda , Ryoya Nakagawa , Sae Okazaki , Hisato Hirano , Kan Kobayashi , Tsukasa Kusakizako , Tomohiro Nishizawa , Keitaro Yamashita , Hiroshi Nishimasu , Osamu Nureki

Kidney GATA3

Cellular & molecular immunology
Avec: Ryota Sakai , Minako Ito , Kyoko Komai , Mana Iizuka-Koga , Kazuhiko Matsuo , Takashi Nakayama , Osamu Yoshie , Koichi Amano , Hiroshi Nishimasu , Osamu Nureki , Masato Kubo , Akihiko Yoshimura

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.

Nature structural & molecular biology
Avec: Kazuhiro Kobayashi , Wataru Shihoya , Tomohiro Nishizawa , Francois Marie Ngako Kadji , Junken Aoki , Asuka Inoue , Osamu Nureki

Identification of Potent

Journal of medicinal chemistry
Avec: Mitsuyasu Kawaguchi , Takayoshi Okabe , Shinichi Okudaira , Kotaro Hama , Kuniyuki Kano , Hiroshi Nishimasu , Hidehiko Nakagawa , Ryuichiro Ishitani , Hirotatsu Kojima , Osamu Nureki , Junken Aoki , Tetsuo Nagano

Structure of the type V-C CRISPR-Cas effector enzyme.

Molecular cell
Avec: Nina Kurihara , Ryoya Nakagawa , Hisato Hirano , Sae Okazaki , Atsuhiro Tomita , Kan Kobayashi , Tsukasa Kusakizako , Tomohiro Nishizawa , Keitaro Yamashita , David A Scott , Hiroshi Nishimasu , Osamu Nureki

The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors.

The Journal of biological chemistry
Avec: Xue-Fei Ma , Ting-Ting Wang , Wen-Hui Wang , Li Guan , Chang-Run Guo , Xing-Hua Li , Yun-Tao Lei , Ying-Zhe Fan , Xiao-Na Yang , Motoyuki Hattori , Osamu Nureki , Michael X Zhu , Ye Yu , Yun Tian , Jin Wang

Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1.

Nature communications
Avec: Tatsuya Hagino , Takafumi Kato , Go Kasuya , Kan Kobayashi , Tsukasa Kusakizako , Shin Hamamoto , Tomoaki Sobajima , Yuichiro Fujiwara , Keitaro Yamashita , Hisashi Kawasaki , Andrés D Maturana , Tomohiro Nishizawa , Osamu Nureki

Lipidic cubic phase serial femtosecond crystallography structure of a photosynthetic reaction centre.

Acta crystallographica. Section D, Structural biology
Avec: Petra Båth , Analia Banacore , Per Börjesson , Robert Bosman , Cecilia Wickstrand , Cecilia Safari , Robert Dods , Swagatha Ghosh , Peter Dahl , Giorgia Ortolani , Tinna Björg Ulfarsdottir , Greger Hammarin , María José García Bonete , Adams Vallejos , Lucija Ostojić , Petra Edlund , Johanna Barbara Linse , Rebecka Andersson , Eriko Nango , Shigeki Owada , Rie Tanaka , Kensuke Tono , Yasumasa Joti , Osamu Nureki , Fangjia Luo , Daniel James , Karol Nass , Philip J M Johnson , Gregor Knopp , Dmitry Ozerov , Claudio Cirelli , Christopher Milne , So Iwata , Gisela Brändén , Richard Neutze

Endogenous ligand recognition and structural transition of a human PTH receptor.

Molecular cell
Avec: Kazuhiro Kobayashi , Kouki Kawakami , Tsukasa Kusakizako , Hirotake Miyauchi , Atsuhiro Tomita , Kan Kobayashi , Wataru Shihoya , Keitaro Yamashita , Tomohiro Nishizawa , Hideaki E Kato , Asuka Inoue , Osamu Nureki

Cryo-EM structure of the transposon-associated TnpB enzyme.

Nature
Avec: Ryoya Nakagawa , Hisato Hirano , Satoshi N Omura , Suchita Nety , Soumya Kannan , Han Altae-Tran , Xiao Yao , Yuriko Sakaguchi , Takayuki Ohira , Wen Y Wu , Hiroshi Nakayama , Yutaro Shuto , Tatsuki Tanaka , Fumiya K Sano , Tsukasa Kusakizako , Yoshiaki Kise , Yuzuru Itoh , Naoshi Dohmae , John van der Oost , Tsutomu Suzuki , Feng Zhang , Osamu Nureki

Structural insights into endothelin receptor signalling.

Journal of biochemistry
Avec: Wataru Shihoya , Fumiya K Sano , Osamu Nureki

Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors.

Science (New York, N.Y.)
Avec: Jagannath Maharana , Fumiya K Sano , Parishmita Sarma , Manish K Yadav , Longhan Duan , Tomasz M Stepniewski , Madhu Chaturvedi , Ashutosh Ranjan , Vinay Singh , Sayantan Saha , Gargi Mahajan , Mohamed Chami , Wataru Shihoya , Jana Selent , Ka Young Chung , Ramanuj Banerjee , Osamu Nureki , Arun K Shukla

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