Salmonella phage akira, infecting selected Salmonella enterica Enteritidis and Typhimurium strains, represents a new lineage of bacteriophages.


Journal

Archives of virology
ISSN: 1432-8798
Titre abrégé: Arch Virol
Pays: Austria
ID NLM: 7506870

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 28 10 2021
accepted: 08 04 2022
pubmed: 29 6 2022
medline: 27 8 2022
entrez: 28 6 2022
Statut: ppublish

Résumé

Some serovars of Salmonella can cause life-threatening diarrhoeal diseases and bacteriemia. The emergence of multidrug-resistant strains has led to a need for alternative treatments such as phage therapy, which requires available, well-described, diverse, and suitable phages. Phage akira was found to lyse 19 out of 32 Salmonella enterica serovars and farm isolates tested, although plaque formation was observed with only two S. Enteritidis and one S. Typhimurium strain. Phage akira encodes anti-defence genes against type 1 R-M systems, is distinct (<65% nucleotide sequence identity) from related phages and has siphovirus morphology. We propose that akira represents a new genus in the class Caudoviricetes.

Identifiants

pubmed: 35764845
doi: 10.1007/s00705-022-05477-9
pii: 10.1007/s00705-022-05477-9
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2049-2056

Subventions

Organisme : Villum Fonden
ID : 17595
Organisme : Aarhus Universitets Forskningsfond
ID : E-2015-FLS-7-28
Organisme : Human Frontier Science Program
ID : RGP0024/2018

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.

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Auteurs

Nikoline S Olsen (NS)

Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, 1871, Frederiksberg, Denmark. sno@plen.ku.dk.

René Lametsch (R)

Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej 26, 1958, Frederiksberg, Denmark.

Natalia Wagner (N)

Institute for Microbiology and Biotechnology, Max Rubner-Institut, Hermann-Weigmann-Str. 1, 24103, Kiel, Denmark.

Lars Hestbjerg Hansen (LH)

Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, 1871, Frederiksberg, Denmark.

Witold Kot (W)

Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen, Thorvaldsensvej 40, 1871, Frederiksberg, Denmark. wk@plen.ku.dk.

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