The Ergogenic Effects of Acute Carbohydrate Feeding on Resistance Exercise Performance: A Systematic Review and Meta-analysis.
Journal
Sports medicine (Auckland, N.Z.)
ISSN: 1179-2035
Titre abrégé: Sports Med
Pays: New Zealand
ID NLM: 8412297
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
accepted:
30
05
2022
pubmed:
10
7
2022
medline:
25
10
2022
entrez:
9
7
2022
Statut:
ppublish
Résumé
Carbohydrate (CHO) ingestion has an ergogenic effect on endurance training performance. Less is known about the effect of acute CHO ingestion on resistance training (RT) performance and equivocal results are reported in the literature. The current systematic review and meta-analysis sought to determine if and to what degree CHO ingestion influences RT performance. PubMed, MEDLINE, SportDiscus, Scopus, and CINAHL databases were searched for peer-reviewed articles written in English that used a cross-over design to assess the acute effect of CHO ingestion on RT performance outcomes (e.g., muscle strength, power, and endurance) in healthy human participants compared to a placebo or water-only conditions. The Cochrane Collaboration's risk of bias tool and GRADE approaches were used to assess risk of bias and certainty of evidence, respectively. Random effects meta-analyses were performed for total training session volume and post-exercise blood lactate and glucose. Sub-group meta-analysis and meta-regression were performed for categorical (session and fast durations) and continuous (total number of maximal effort sets, load used, and CHO dose) covariates, respectively. Twenty-one studies met the inclusion criteria (n = 226 participants). Pooled results revealed a significant benefit of CHO ingestion in comparison to a placebo or control for total session training volume (standardised mean difference [SMD] = 0.61). Sub-group analysis revealed a significant benefit of CHO ingestion during sessions longer than 45 min (SMD = 1.02) and after a fast duration of 8 h or longer (SMD = 0.39). Pooled results revealed elevated post-exercise blood lactate (SMD = 0.58) and blood glucose (SMD = 2.36) with CHO ingestion. Meta-regression indicated that the number of maximal effort sets, but not CHO dose or load used, moderates the effect of CHO ingestion on RT performance (beta co-efficient [b] = 0.11). Carbohydrate dose does not moderate post-exercise lactate accumulation nor do maximal effort sets completed, load used, and CHO dose moderate the effect of CHO ingestion on post-exercise blood glucose. Carbohydrate ingestion has an ergogenic effect on RT performance by enhancing volume performance, which is more likely to occur when sessions exceed 45 min and where the fast duration is ≥ 8 h. Further, the effect is moderated by the number of maximal effort sets completed, but not the load used or CHO dose. Post-exercise blood lactate is elevated following CHO ingestion but may come at the expense of an extended time-course of recovery due to the additional training volume performed. Post-exercise blood glucose is elevated when CHO is ingested during RT, but it is presently unclear if it has an impact on RT performance. The original protocol was prospectively registered on the Open Science Framework (Project identifier: https://doi.org/10.17605/OSF.IO/HJFBW ).
Sections du résumé
BACKGROUND
Carbohydrate (CHO) ingestion has an ergogenic effect on endurance training performance. Less is known about the effect of acute CHO ingestion on resistance training (RT) performance and equivocal results are reported in the literature.
OBJECTIVE
The current systematic review and meta-analysis sought to determine if and to what degree CHO ingestion influences RT performance.
METHODS
PubMed, MEDLINE, SportDiscus, Scopus, and CINAHL databases were searched for peer-reviewed articles written in English that used a cross-over design to assess the acute effect of CHO ingestion on RT performance outcomes (e.g., muscle strength, power, and endurance) in healthy human participants compared to a placebo or water-only conditions. The Cochrane Collaboration's risk of bias tool and GRADE approaches were used to assess risk of bias and certainty of evidence, respectively. Random effects meta-analyses were performed for total training session volume and post-exercise blood lactate and glucose. Sub-group meta-analysis and meta-regression were performed for categorical (session and fast durations) and continuous (total number of maximal effort sets, load used, and CHO dose) covariates, respectively.
RESULTS
Twenty-one studies met the inclusion criteria (n = 226 participants). Pooled results revealed a significant benefit of CHO ingestion in comparison to a placebo or control for total session training volume (standardised mean difference [SMD] = 0.61). Sub-group analysis revealed a significant benefit of CHO ingestion during sessions longer than 45 min (SMD = 1.02) and after a fast duration of 8 h or longer (SMD = 0.39). Pooled results revealed elevated post-exercise blood lactate (SMD = 0.58) and blood glucose (SMD = 2.36) with CHO ingestion. Meta-regression indicated that the number of maximal effort sets, but not CHO dose or load used, moderates the effect of CHO ingestion on RT performance (beta co-efficient [b] = 0.11). Carbohydrate dose does not moderate post-exercise lactate accumulation nor do maximal effort sets completed, load used, and CHO dose moderate the effect of CHO ingestion on post-exercise blood glucose.
CONCLUSIONS
Carbohydrate ingestion has an ergogenic effect on RT performance by enhancing volume performance, which is more likely to occur when sessions exceed 45 min and where the fast duration is ≥ 8 h. Further, the effect is moderated by the number of maximal effort sets completed, but not the load used or CHO dose. Post-exercise blood lactate is elevated following CHO ingestion but may come at the expense of an extended time-course of recovery due to the additional training volume performed. Post-exercise blood glucose is elevated when CHO is ingested during RT, but it is presently unclear if it has an impact on RT performance.
PROTOCOL REGISTRATION
The original protocol was prospectively registered on the Open Science Framework (Project identifier: https://doi.org/10.17605/OSF.IO/HJFBW ).
Identifiants
pubmed: 35809162
doi: 10.1007/s40279-022-01716-w
pii: 10.1007/s40279-022-01716-w
pmc: PMC9584980
doi:
Substances chimiques
Performance-Enhancing Substances
0
Blood Glucose
0
Water
059QF0KO0R
Lactates
0
Types de publication
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2691-2712Informations de copyright
© 2022. The Author(s).
Références
Romijn J, Coyle E, Sidossis L, Gastaldelli A, Horowitz J, Endert E, et al. Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am J Physiol Endocrinol Metab. 1993;265(3):E380–91.
doi: 10.1152/ajpendo.1993.265.3.E380
van Loon LJ, Greenhaff PL, Constantin-Teodosiu D, Saris WH, Wagenmakers AJ. The effects of increasing exercise intensity on muscle fuel utilisation in humans. J Physiol. 2001;536(1):295–304.
pubmed: 11579177
pmcid: 2278845
doi: 10.1111/j.1469-7793.2001.00295.x
Vigh-Larsen JF, Ørtenblad N, Spriet LL, Overgaard K, Mohr M. Muscle glycogen metabolism and high-intensity exercise performance: a narrative review. Sports Med. 2021;51(9):1855–74.
pubmed: 33900579
doi: 10.1007/s40279-021-01475-0
Kraemer WJ, Ratamess NA, French DN. Resistance training for health and performance. Curr Sports Med Rep. 2002;1(3):165–71.
pubmed: 12831709
doi: 10.1249/00149619-200206000-00007
Ormsbee MJ, Bach CW, Baur DA. Pre-exercise nutrition: the role of macronutrients, modified starches and supplements on metabolism and endurance performance. Nutrients. 2014;6(5):1782–808.
pubmed: 24787031
pmcid: 4042570
doi: 10.3390/nu6051782
Cermak NM, van Loon LJ. The use of carbohydrates during exercise as an ergogenic aid. Sports Med. 2013;43(11):1139–55.
pubmed: 23846824
doi: 10.1007/s40279-013-0079-0
Rothschild JA, Kilding AE, Plews DJ. What should I eat before exercise? Pre-exercise nutrition and the response to endurance exercise: Current prospective and future directions. Nutrients. 2020;12(11):3473.
pmcid: 7696145
doi: 10.3390/nu12113473
Cholewa JM, Newmire DE, Zanchi NE. Carbohydrate restriction: friend or foe of resistance-based exercise performance? Nutrition. 2019;60:136–46.
pubmed: 30586657
doi: 10.1016/j.nut.2018.09.026
Egan B, Zierath JR. Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metab. 2013;17(2):162–84.
pubmed: 23395166
doi: 10.1016/j.cmet.2012.12.012
Hargreaves M, Spriet LL. Skeletal muscle energy metabolism during exercise. Nat Metab. 2020;2(9):817–28.
pubmed: 32747792
doi: 10.1038/s42255-020-0251-4
Koopman R, Manders RJ, Jonkers RA, Hul GB, Kuipers H, van Loon LJ. Intramyocellular lipid and glycogen content are reduced following resistance exercise in untrained healthy males. Eur J Appl Physiol. 2006;96(5):525–34.
pubmed: 16369816
doi: 10.1007/s00421-005-0118-0
MacDougall JD, Ray S, Sale DG, McCartney N, Lee P, Garner S. Muscle substrate utilization and lactate production during weightlifting. Can J Appl Physiol. 1999;24(3):209–15.
pubmed: 10364416
doi: 10.1139/h99-017
Tesch PA, Colliander EB, Kaiser P. Muscle metabolism during intense, heavy-resistance exercise. Eur J Appl Physiol Occup Physiol. 1986;55(4):362–6.
pubmed: 3758035
doi: 10.1007/BF00422734
Pascoe D, Costill DL, Fink WJ, Robergs RA, Zachweija JJ. Glycogen resynthesis in skeletal muscle following resistive exercise. Med Sci Sports Exerc. 1993;25:349–54.
pubmed: 8455450
doi: 10.1249/00005768-199303000-00009
Robergs RA, Pearson DR, Costill DL, Fink WJ, Pascoe DD, Benedict MA, et al. Muscle glycogenolysis during differing intensities of weight-resistance exercise. J Appl Physiol. 1991;70(4):1700–6.
pubmed: 2055849
doi: 10.1152/jappl.1991.70.4.1700
Ørtenblad N, Nielsen J. Muscle glycogen and cell function–location, location, location. Scand J Med Sci Sports. 2015;25:34–40.
pubmed: 26589115
doi: 10.1111/sms.12599
Nielsen J, Schrøder H, Rix C, Ørtenblad N. Distinct effects of subcellular glycogen localization on tetanic relaxation time and endurance in mechanically skinned rat skeletal muscle fibres. J Physiol. 2009;587(14):3679–90.
pubmed: 19470780
pmcid: 2742290
doi: 10.1113/jphysiol.2009.174862
Ørtenblad N, Nielsen J, Saltin B, Holmberg HC. Role of glycogen availability in sarcoplasmic reticulum Ca2+ kinetics in human skeletal muscle. J Physiol. 2011;589(3):711–25.
pubmed: 21135051
doi: 10.1113/jphysiol.2010.195982
Nielsen J, Cheng AJ, Ørtenblad N, Westerblad H. Subcellular distribution of glycogen and decreased tetanic Ca2+ in fatigued single intact mouse muscle fibres. J Physiol. 2014;592(9):2003–12.
pubmed: 24591577
pmcid: 4230775
doi: 10.1113/jphysiol.2014.271528
Hokken R, Laugesen S, Aagaard P, Suetta C, Frandsen U, Ørtenblad N, et al. Subcellular localization-and fibre type-dependent utilization of muscle glycogen during heavy resistance training in elite power and weightlifters. Acta Physiol. 2020;231(2): e13561.
Knapik JJ, Meredith CN, Jones BH, Suek L, Young VR, Evans WJ. Influence of fasting on carbohydrate and fat metabolism during rest and exercise in men. J App Physiol. 1988;64(5):1923–9.
doi: 10.1152/jappl.1988.64.5.1923
Rothman DL, Magnusson I, Katz LD, Shulman RG, Shulman GI. Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR. Science. 1991;254(5031):573–6.
pubmed: 1948033
doi: 10.1126/science.1948033
Nilsson LH, Hultman E. Liver glycogen in man–the effect of total starvation or a carbohydrate-poor diet followed by carbohydrate refeeding. Scand J Clin Lab Invest. 1973;32(4):325–30.
pubmed: 4771102
doi: 10.3109/00365517309084355
Chryssanthopoulos C, Williams C, Nowitz A, Bogdanis G. Skeletal muscle glycogen concentration and metabolic responses following a high glycaemic carbohydrate breakfast. J Sports Sci. 2004;22(11–12):1065–71.
pubmed: 15801500
doi: 10.1080/02640410410001730007
Wee S-L, Williams C, Tsintzas K, Boobis L. Ingestion of a high-glycemic index meal increases muscle glycogen storage at rest but augments its utilization during subsequent exercise. J App Physiol. 2005;99(2):707–14.
doi: 10.1152/japplphysiol.01261.2004
Taylor R, Price T, Katz L, Shulman R, Shulman G. Direct measurement of change in muscle glycogen concentration after a mixed meal in normal subjects. Am J Physiol Endocrinol Metab. 1993;265(2):E224–9.
doi: 10.1152/ajpendo.1993.265.2.E224
Coyle EF, Coggan A, Hemmert M, Lowe R, Walters T. Substrate usage during prolonged exercise following a preexercise meal. J App Physiol. 1985;59(2):429–33.
doi: 10.1152/jappl.1985.59.2.429
Haff GG, Lehmkuhl MJ, McCoy LB, Stone MH. Carbohydrate supplementation and resistance training. J Strength Cond Res. 2003;17(1):187–96.
pubmed: 12580676
Jeukendrup AE. Carbohydrate intake during exercise and performance. Nutrition. 2004;20(7–8):669–77.
pubmed: 15212750
doi: 10.1016/j.nut.2004.04.017
Chambers E, Bridge M, Jones D. Carbohydrate sensing in the human mouth: effects on exercise performance and brain activity. J Physiol. 2009;587(8):1779–94.
pubmed: 19237430
pmcid: 2683964
doi: 10.1113/jphysiol.2008.164285
Gant N, Stinear CM, Byblow WD. Carbohydrate in the mouth immediately facilitates motor output. Brain Res. 2010;1350:151–8.
pubmed: 20388497
doi: 10.1016/j.brainres.2010.04.004
Laurenson DM, Dubé DJ. Effects of carbohydrate and protein supplementation during resistance exercise on respiratory exchange ratio, blood glucose, and performance. J Clin Transl Endocrinol. 2015;2(1):1–5.
pubmed: 29159102
Aoki MS, Pontes FL Jr, Navarro F, Uchida MC, Bacurau RFP. Carbohydrate supplementation fails to revert the deleterious effects of endurance exercise upon subsequent strength performance. Rev Bras Med Esporte. 2003;9(5):288–92.
Haff G, Koch A, Potteiger J, Kuphal K, Magee L, Green S, et al. Carbohydrate supplementation attenuates muscle glycogen loss during acute bouts of resistance exercise. Int J Sport Nutr Exerc Metab. 2000;10(3):326–39.
pubmed: 10997956
doi: 10.1123/ijsnem.10.3.326
Haff G, Schroeder C, Koch A, Kuphal K, Comeau M, Potteiger J. The effects of supplemental carbohydrate ingestion on intermittent isokinetic leg exercise. J Sports Med Phys Fitness. 2001;41(2):216–22.
pubmed: 11447365
Fairchild TJ, Dillon P, Curtis C, Dempsey AR. Glucose ingestion does not improve maximal isokinetic force. J Strength Cond Res. 2016;30(1):194–9.
pubmed: 26691410
doi: 10.1519/JSC.0000000000001057
Vincent K, Clarkson P, Freedson P, DeCheke M. Effect of a pre-exercise liquid, high carbohydrate feeding on resistance exercise performance. Med Sci Sports Exerc. 1993;25(5):S194.
doi: 10.1249/00005768-199305001-01095
Haff G, Stone M, Warren B, Keith R, Johnson R, Nieman D, et al. The effect of carbohydrate supplementation on multiple sessions and bouts of resistance exercise. J Strength Cond Res. 1999;13(2):111–7.
Lambert CP, Flynn MG, Boone JB Jr, Michaud TJ, Rodriguez-Zayas J. Effects of carbohydrate feeding on multiple-bout resistance exercise. J Strength Cond Res. 1991;5(4):192–7.
Krings B, Rountree J, McAllister M, Cummings P, Peterson T, Fountain B, et al. Effects of acute carbohydrate ingestion on anaerobic exercise performance. J Int Soc Sports Nutr. 2016;13(1):40.
pubmed: 27843418
pmcid: 5105234
doi: 10.1186/s12970-016-0152-9
Smith JW, Krings BM, Shepherd BD, Waldman HS, Basham SA, McAllister MJ. Effects of carbohydrate and branched-chain amino acid beverage ingestion during acute upper body resistance exercise on performance and postexercise hormone response. Appl Physiol Nutr Metab. 2018;43(5):504–9.
pubmed: 29244956
doi: 10.1139/apnm-2017-0563
Kulik JR, Touchberry CD, Kawamori N, Blumert PA, Crum AJ, Haff GG. Supplemental carbohydrate ingestion does not improve performance of high-intensity resistance exercise. J Strength Cond Res. 2008;22(4):1101–7.
pubmed: 18545201
doi: 10.1519/JSC.0b013e31816d679b
Wilburn DT, Machek SB, Cardaci TD, Hwang PS, Willoughby DS. Acute maltodextrin supplementation during resistance exercise. J Sports Sci Med. 2020;19(2):282–8.
pubmed: 32390721
pmcid: 7196753
Wax B, Brown SP, Webb HE, Kavazis AN. Effects of carbohydrate supplementation on force output and time to exhaustion during static leg contractions superimposed with electromyostimulation. J Strength Cond Res. 2012;26(6):1717–23.
pubmed: 22614150
doi: 10.1519/JSC.0b013e318234ec0e
Wax B, Kavazis AN, Brown SP. Effects of supplemental carbohydrate ingestion during superimposed electromyostimulation exercise in elite weightlifters. J Strength Cond Res. 2013;27(11):3084–90.
pubmed: 23442284
doi: 10.1519/JSC.0b013e31828c26ec
Oliver JM, Almada AL, Van Eck LE, Shah M, Mitchell JB, Jones MT, et al. Ingestion of high molecular weight carbohydrate enhances subsequent repeated maximal power: a randomized controlled trial. PLoS ONE. 2016;11(9):e0163009.
pubmed: 27636206
pmcid: 5026365
doi: 10.1371/journal.pone.0163009
Henselmans M, Bjørnsen T, Hedderman R, Vårvik F. The effect of carbohydrate intake on strength and resistance training performance: a systematic review. Nutrients. 2022;14(4):856.
pubmed: 35215506
pmcid: 8878406
doi: 10.3390/nu14040856
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71.
pubmed: 33782057
pmcid: 8005924
doi: 10.1136/bmj.n71
Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366: l4898.
pubmed: 31462531
doi: 10.1136/bmj.l4898
Hecksteden A, Faude O, Meyer T, Donath L. How to construct, conduct and analyze an exercise training study? Front Physiol. 2018;9:1007.
pubmed: 30140237
pmcid: 6094975
doi: 10.3389/fphys.2018.01007
Thomas D, Erdman K, Burke L. Position of the academy of nutrition and dietetics, dietitians of Canada, and the American College of Sports Medicine: nutrition and athletic performance. J Acad Nutr Diet. 2016;116(3):501–28.
pubmed: 26920240
doi: 10.1016/j.jand.2015.12.006
Mirizio G, Nunes R, Vargas D, Foster C, Vieira E. Time-of-day effects on short-duration maximal exercise performance. Sci Rep. 2020;10(1):9485.
pubmed: 32528038
pmcid: 7289891
doi: 10.1038/s41598-020-66342-w
Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, et al. Grading quality of evidence and strength of recommendations. BMJ. 2004;328(7454):1490.
pubmed: 15205295
doi: 10.1136/bmj.328.7454.1490
Miller JR, Van Hooren B, Bishop C, Buckley JD, Willy RW, Fuller JT. A systematic review and meta-analysis of crossover studies comparing physiological, perceptual and performance measures between treadmill and overground running. Sports Med. 2019;49(5):763–82.
pubmed: 30847825
doi: 10.1007/s40279-019-01087-9
Jukic I, García Ramos A, Helms E, McGuigan M, Tufano J. Acute effects of cluster and rest redistribution set structures on mechanical, metabolic, and perceptual fatigue during and after resistance training: a systematic review and meta-analysis. Sports Med. 2020;50(12):2209–36.
pubmed: 32901442
doi: 10.1007/s40279-020-01344-2
Jukic I, Van Hooren B, Ramos AG, Helms ER, McGuigan MR, Tufano JJ. The effects of set structure manipulation on chronic adaptations to resistance training: a Systematic review and meta-analysis. Sports Med. 2021;51(5):1061–86.
pubmed: 33417154
doi: 10.1007/s40279-020-01423-4
R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. 2021. https://www.R-project.org/ .
Schwarzer G, Carpenter JR, Rücker G. Meta-analysis with R. New York: Springer; 2015.
doi: 10.1007/978-3-319-21416-0
Viechtbauer W. Conducting meta-analyses in R with the metafor package. J Stat Softw. 2010;36(3):1–48.
doi: 10.18637/jss.v036.i03
Veroniki AA, Jackson D, Viechtbauer W, Bender R, Bowden J, Knapp G, et al. Methods to estimate the between-study variance and its uncertainty in meta-analysis. Res Synth Methods. 2016;7(1):55–79.
pubmed: 26332144
doi: 10.1002/jrsm.1164
Knapp G, Hartung J. Improved tests for a random effects meta-regression with a single covariate. Stat Med. 2003;22(17):2693–710.
pubmed: 12939780
doi: 10.1002/sim.1482
IntHout J, Ioannidis JP, Borm GF. The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method. BMC Med Res Methodol. 2014;14(1):1–12.
doi: 10.1186/1471-2288-14-25
Borenstein M, Hedges LV, Higgins JP, Rothstein HR. Introduction to meta-analysis. New York: Wiley; 2011.
Cohen J. Statistical power analysis for the behavioral sciences. New York: Academic press; 1988.
Fu R, Gartlehner G, Grant M, Shamliyan T, Sedrakyan A, Wilt TJ, et al. Conducting quantitative synthesis when comparing medical interventions: AHRQ and the Effective Health Care Program. J Clin Epidemiol. 2011;64(11):1187–97.
pubmed: 21477993
doi: 10.1016/j.jclinepi.2010.08.010
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–60.
pubmed: 12958120
pmcid: 192859
doi: 10.1136/bmj.327.7414.557
Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–34.
pubmed: 9310563
pmcid: 2127453
doi: 10.1136/bmj.315.7109.629
Chandler J, Cumpston M, Li T, Page M, Welch V. Cochrane handbook for systematic reviews of interventions. Hoboken: Wiley; 2019.
Rountree JA, Krings BM, Peterson TJ, Thigpen AG, McAllister MJ, Holmes ME, et al. Efficacy of carbohydrate ingestion on crossfit exercise performance. Sports. 2017;5(3):61.
pmcid: 5968949
doi: 10.3390/sports5030061
dos Santos MPP, Spineli H, Bastos-silva VJ, Learsi SK, de Araujo GG. Ingestion of a drink containing carbohydrate increases the number of bench press repetitions. Rev de Nutr. 2019. https://doi.org/10.1590/1678-9865201932e180056 .
doi: 10.1590/1678-9865201932e180056
Ballard TP, Melby CL, Camus H, Cianciulli M, Pitts J, Schmidt S, et al. Effect of resistance exercise, with or without carbohydrate supplementation, on plasma ghrelin concentrations and postexercise hunger and food intake. Metab Clin Exp. 2009;58(8):1191–9.
pubmed: 19497597
doi: 10.1016/j.metabol.2009.03.018
Battazza RA, Suzuki FS, Kalytczak MM, Paunksnis MR, Politi F, Evangelista AL, et al. Effects of previous carbohydrate supplementation on muscular fatigue: double-blind, randomized, placebo-controlled crossover study. Mot Rev de Educ Fis. 2019. https://doi.org/10.1590/s1980-6574201900010004 .
doi: 10.1590/s1980-6574201900010004
Bird SP, Mabon T, Pryde M, Feebrey S, Cannon J. Triphasic multinutrient supplementation during acute resistance exercise improves session volume load and reduces muscle damage in strength-trained athletes. Nutr Res. 2013;33(5):376–87.
pubmed: 23684439
doi: 10.1016/j.nutres.2013.03.002
Bin Naharudin MN, Yusof A, Shaw H, Stockton M, Clayton DJ, James LJ. Breakfast omission reduces subsequent resistance exercise performance. J Strength Cond Res. 2019;33(7):1766–72.
pubmed: 30707135
doi: 10.1519/JSC.0000000000003054
Naharudin M, Adams J, Richardson H, Thomson T, Oxinou C, Marshall C, et al. Viscous placebo and carbohydrate breakfasts similarly decrease appetite and increase resistance exercise performance compared to a control breakfast in trained males. Br J Nutr. 2020;124:1–25.
doi: 10.1017/S0007114520001002
Pöchmüller M, Schwingshackl L, Colombani PC, Hoffmann G. A systematic review and meta-analysis of carbohydrate benefits associated with randomized controlled competition-based performance trials. J Int Soc Sports Nutr. 2016;13(1):27.
pubmed: 27408608
pmcid: 4940907
doi: 10.1186/s12970-016-0139-6
Temesi J, Johnson NA, Raymond J, Burdon CA, O’Connor HT. Carbohydrate ingestion during endurance exercise improves performance in adults. J Nutr. 2011;141(5):890–7.
pubmed: 21411610
doi: 10.3945/jn.110.137075
Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2018;15(1):11.
pubmed: 29527137
pmcid: 5839013
doi: 10.1186/s12970-018-0216-0
Trexler ET, Persky AM, Ryan ED, Schwartz TA, Stoner L, Smith-Ryan AE. Acute effects of citrulline supplementation on high-intensity strength and power performance: a systematic review and meta-analysis. Sports Med. 2019;49(5):707–18.
pubmed: 30895562
doi: 10.1007/s40279-019-01091-z
Rodríguez-Rosell D, Yáñez-García JM, Sánchez-Medina L, Mora-Custodio R, González-Badillo JJ. Relationship between velocity loss and repetitions in reserve in the bench press and back squat exercises. J Strength Cond Res. 2020;34(9):2537–47.
pubmed: 31045753
doi: 10.1519/JSC.0000000000002881
Rodríguez-Rosell D, Yáñez-García JM, Mora-Custodio R, Torres-Torrelo J, Ribas-Serna J, González-Badillo JJ. Role of the effort index in predicting neuromuscular fatigue during resistance exercises. J Strength Cond Res. 2020. https://doi.org/10.1519/JSC.0000000000003805 .
doi: 10.1519/JSC.0000000000003805
pubmed: 33337706
Rodríguez-Rosell D, Yáñez-García JM, Torres-Torrelo J, Mora-Custodio R, Marques MC, González-Badillo JJ. Effort index as a novel variable for monitoring the level of effort during resistance exercises. J Strength Cond Res. 2018;32(8):2139–53.
pubmed: 29781942
doi: 10.1519/JSC.0000000000002629
Goforth HW Jr, Arnall DA, Bennett BL, Law PG. Persistence of supercompensated muscle glycogen in trained subjects after carbohydrate loading. J Appl Physiol. 1997;82(1):342–7.
pubmed: 9029236
doi: 10.1152/jappl.1997.82.1.342
Jacobs I. Lactate concentrations after short, maximal exercise at various glycogen levels. Acta Physiol Scand. 1981;111(4):465–9.
pubmed: 7304208
doi: 10.1111/j.1748-1716.1981.tb06764.x
Ferguson BS, Rogatzki MJ, Goodwin ML, Kane DA, Rightmire Z, Gladden LB. Lactate metabolism: historical context, prior misinterpretations, and current understanding. Eur J Appl Physiol. 2018;118(4):691–728.
pubmed: 29322250
doi: 10.1007/s00421-017-3795-6
Sánchez-Medina L, González-Badillo JJ. Velocity loss as an indicator of neuromuscular fatigue during resistance training. Med Sci Sports Exerc. 2011;43(9):1725–34.
pubmed: 21311352
doi: 10.1249/MSS.0b013e318213f880
Morcillo JA, Jiménez-Reyes P, Cuadrado-Peñafiel V, Lozano E, Ortega-Becerra M, Párraga J. Relationships between repeated sprint ability, mechanical parameters, and blood metabolites in professional soccer players. J Strength Cond Res. 2015;29(6):1673–82.
pubmed: 25463691
doi: 10.1519/JSC.0000000000000782
Keul J, Haralambie G, Bruder M, Gottstein H. The effect of weight lifting exercise on heart rate and metabolism in experienced weight lifters. Med Sci Sports. 1978;10(1):13–5.
pubmed: 672545
Hargreaves M, Costill DL, Coggan A, Fink WJ, Nishibata I. Effect of carbohydrate feedings on muscle glycogen utilization and exercise performance. Med Sci Sports Exerc. 1984;16(3):219–22.
pubmed: 6748917
doi: 10.1249/00005768-198406000-00004
Hopewell S, McDonald S, Clarke M, Egger M. Grey literature in meta-analyses of randomized trials of health care interventions. Cochrane Database Syst Rev. 2007;2007(2):Mr000010.
pmcid: 8973936
Naharudin MN, Yusof A, Clayton DJ, James LJ. Starving your performance? Reduced preexercise hunger increases resistance exercise performance. Int J Sports Physiol. 2021. https://doi.org/10.1123/ijspp.2021-0166 .
doi: 10.1123/ijspp.2021-0166
Betts JA, Gonzalez JT, Burke LM, Close GL, Garthe I, James LJ, et al. PRESENT 2020: text expanding on the checklist for proper reporting of evidence in sport and exercise nutrition trials. Int J Sport Nutr Exerc Metab. 2020;30(1):2–13.
pubmed: 31945740
doi: 10.1123/ijsnem.2019-0326