Neurotensin orchestrates valence assignment in the amygdala.

Basolateral Nuclear Complex / cytology Calcium / metabolism Cues Learning Neural Pathways Neuronal Plasticity Neurotensin / metabolism Optogenetics Punishment Reward Thalamic Nuclei / cytology

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
08 2022
Historique:
received: 22 02 2018
accepted: 10 06 2022
pubmed: 22 7 2022
medline: 20 8 2022
entrez: 21 7 2022
Statut: ppublish

Résumé

The ability to associate temporally segregated information and assign positive or negative valence to environmental cues is paramount for survival. Studies have shown that different projections from the basolateral amygdala (BLA) are potentiated following reward or punishment learning

Identifiants

DOI: 10.1038/s41586-022-04964-y PMID: 35859170 PMC: PMC9583860
pubmed: 35859170
doi: 10.1038/s41586-022-04964-y
pii: 10.1038/s41586-022-04964-y
pmc: PMC9583860
mid: NIHMS1840566
doi:

Substances chimiques

Neurotensin 39379-15-2
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

586-592

Subventions

Organisme : NIMH NIH HHS
ID : K99 MH124435
Pays : United States
Organisme : NIMH NIH HHS
ID : F32 MH111216
Pays : United States
Organisme : NIMH NIH HHS
ID : R00 MH124435
Pays : United States
Organisme : NIMH NIH HHS
ID : R37 MH102441
Pays : United States
Organisme : NINDS NIH HHS
ID : T32 NS007292
Pays : United States
Organisme : NIMH NIH HHS
ID : P50 MH115874
Pays : United States
Organisme : NIDA NIH HHS
ID : K99 DA055111
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH108665
Pays : United States
Organisme : NCCIH NIH HHS
ID : DP1 AT009925
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM133351
Pays : United States
Organisme : NIMH NIH HHS
ID : F32 MH115446
Pays : United States
Organisme : NIDDK NIH HHS
ID : DP2 DK102256
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH102441
Pays : United States
Organisme : NIDA NIH HHS
ID : R00 DA045103
Pays : United States
Organisme : NIDA NIH HHS
ID : K99 DA045103
Pays : United States

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Hao Li (H)

Salk Institute for Biological Studies, La Jolla, CA, USA.

Praneeth Namburi (P)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

Jacob M Olson (JM)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Neuroscience Program, Department of Psychology, Volen National Center for Complex Systems, Brandeis University, Waltham, MA, USA.
ORCID: 0000-0001-6351-3274

Matilde Borio (M)

Salk Institute for Biological Studies, La Jolla, CA, USA.
The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

Mackenzie E Lemieux (ME)

Salk Institute for Biological Studies, La Jolla, CA, USA.
The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
ORCID: 0000-0001-6015-8668

Anna Beyeler (A)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
University of Bordeaux, Neurocentre Magendie, INSERM 1215, Bordeaux, France.
ORCID: 0000-0003-2371-5706

Gwendolyn G Calhoon (GG)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Neuroscience Program, Bates College, Lewiston, ME, USA.

Natsuko Hitora-Imamura (N)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.

Austin A Coley (AA)

Salk Institute for Biological Studies, La Jolla, CA, USA.

Avraham Libster (A)

Salk Institute for Biological Studies, La Jolla, CA, USA.
The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

Aneesh Bal (A)

Salk Institute for Biological Studies, La Jolla, CA, USA.
Behavioral Neuroscience, Department of Psychology, Michigan State University, East Lansing, MI, USA.

Xin Jin (X)

Society of Fellows, Harvard University, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
ORCID: 0000-0003-2344-992X

Huan Wang (H)

State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Peking-Tsinghua Center for Life Science, IDG/McGovern Institute for Brain Research at PKU, Beijing, China.

Caroline Jia (C)

Salk Institute for Biological Studies, La Jolla, CA, USA.
Neuroscience Graduate Program, University of California San Diego, La Jolla, CA, USA.

Sourav R Choudhury (SR)

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Xi Shi (X)

Broad Institute of MIT and Harvard, Cambridge, MA, USA.
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.

Ada C Felix-Ortiz (AC)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

Verónica de la Fuente (V)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Instituto de Fisiología, Biología Molecular y Neurociencias (IFIBYNE-UBA-CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.

Vanessa P Barth (VP)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Department of Electrical and Computer Engineering, Technical University of Munich, Munich, Germany.

Hunter O King (HO)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Whitehead Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.

Ehsan M Izadmehr (EM)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.

Jasmin S Revanna (JS)

Salk Institute for Biological Studies, La Jolla, CA, USA.
Biological Sciences Graduate Program, University of California San Diego, La Jolla, CA, USA.

Kanha Batra (K)

Salk Institute for Biological Studies, La Jolla, CA, USA.
Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USA.
ORCID: 0000-0001-6401-4274

Kyle B Fischer (KB)

Salk Institute for Biological Studies, La Jolla, CA, USA.

Laurel R Keyes (LR)

Salk Institute for Biological Studies, La Jolla, CA, USA.

Nancy Padilla-Coreano (N)

Salk Institute for Biological Studies, La Jolla, CA, USA.
ORCID: 0000-0001-9293-2697

Cody A Siciliano (CA)

The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Vanderbilt Center for Addiction Research, Department of Pharmacology, Vanderbilt University, Nashville, TN, USA.
ORCID: 0000-0001-9871-2089

Kenneth M McCullough (KM)

Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.
Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0003-4908-2302

Romy Wichmann (R)

Salk Institute for Biological Studies, La Jolla, CA, USA.
The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
ORCID: 0000-0002-4506-8813

Kerry J Ressler (KJ)

Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.
Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0002-5158-1103

Ila R Fiete (IR)

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
ORCID: 0000-0003-4738-2539

Feng Zhang (F)

Broad Institute of MIT and Harvard, Cambridge, MA, USA.
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Stanley Center for Psychiatric Research, Cambridge, MA, USA.
ORCID: 0000-0003-0178-7995

Yulong Li (Y)

State Key Laboratory of Membrane Biology, Peking University School of Life Sciences, Peking-Tsinghua Center for Life Science, IDG/McGovern Institute for Brain Research at PKU, Beijing, China.
ORCID: 0000-0002-9166-9919

Kay M Tye (KM)

Salk Institute for Biological Studies, La Jolla, CA, USA. tye@salk.edu.
The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. tye@salk.edu.
Systems Neuroscience Laboratory and Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA, USA. tye@salk.edu.
ORCID: 0000-0002-2435-0182

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Classifications MeSH

questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Noyaux gris centraux › Amygdale (système limbique) › Groupe nucléaire basolatéral › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Signaux › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Phénomènes psychologiques › Psychologie appliquée › Apprentissage › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Système nerveux › Voies nerveuses › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Plasticité neuronale › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Neuropeptides › Neurotensine › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Optogénétique › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Sciences sociales › Sociologie › Contrôle social informel › Punition › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Renforcement (psychologie) › Récompense › Neurotensin orchestrates valence assignment in...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Diencéphale › Thalamus › Noyaux du thalamus › Neurotensin orchestrates valence assignment in...