One-step double network hydrogels of photocurable monomers and bacterial cellulose fibers.
Acrylic acid
Bacterial cellulose nanofibers
Biocompatible hydrogel
Double network
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
15 Oct 2022
15 Oct 2022
Historique:
received:
10
03
2022
revised:
25
05
2022
accepted:
21
06
2022
entrez:
22
7
2022
pubmed:
23
7
2022
medline:
27
7
2022
Statut:
ppublish
Résumé
Soft-tissue replacements are challenging due to the stringent compliance requirements for the implanted materials in terms of biocompatibility, durability, high wear resistance, low friction, and water content. Acrylate hydrogels are worth considering as soft tissue implants as they can be photocurable and sustain customized shapes through 3D bioprinting. However, acrylate-based hydrogels present weak mechanical properties and significant dimensional changes when immersed in liquids. To address these obstacles, we fabricated double network (DN) hydrogels composed of polyacrylic acid (PAA) and bacterial cellulose nanofibers (BCNFs) by one fast UV photopolymerization step. BCNFs/PAA hydrogels with a 0.5 wt% BCNFs content present an increased stiffness and a lower, non-pH-dependent swelling than PAA hydrogels or PAA hydrogels with cellulose nanocrystals. Besides, BCNFs/PAA hydrogels are biocompatible and can be frozen/thawed. Those characteristics endorse these hybrid hydrogels as potential candidates for vascular and cartilage tissue implants.
Identifiants
pubmed: 35868754
pii: S0144-8617(22)00683-X
doi: 10.1016/j.carbpol.2022.119778
pii:
doi:
Substances chimiques
Acrylates
0
Biocompatible Materials
0
Hydrogels
0
Cellulose
9004-34-6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
119778Informations de copyright
Copyright © 2022. Published by Elsevier Ltd.