Aiming to improve binding of porphyrin diphenyl guanidinium conjugates to guanine-quadruplexes: When size matters.
Diphenyl guanidines
Docking
Guanine-quadruplexes
UV thermal melting
Journal
Bioorganic & medicinal chemistry letters
ISSN: 1464-3405
Titre abrégé: Bioorg Med Chem Lett
Pays: England
ID NLM: 9107377
Informations de publication
Date de publication:
01 11 2022
01 11 2022
Historique:
received:
31
05
2022
revised:
12
08
2022
accepted:
22
08
2022
pubmed:
29
8
2022
medline:
4
10
2022
entrez:
28
8
2022
Statut:
ppublish
Résumé
Aiming to improve the binding to Guanine quadruplexes of different topologies, docking studies of porphyrin diphenyl guanidine conjugates previously prepared with an O or a S bridge between the diphenyl moiety and a newly design derivative with an SO
Identifiants
pubmed: 36031019
pii: S0960-894X(22)00430-9
doi: 10.1016/j.bmcl.2022.128954
pii:
doi:
Substances chimiques
Biphenyl Compounds
0
Porphyrins
0
diphenyl
2L9GJK6MGN
DNA
9007-49-2
Guanidine
JU58VJ6Y3B
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
128954Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.