Aptamer/Hydroxyapatite-Functionalized Titanium Substrate Promotes Implant Osseointegration via Recruiting Mesenchymal Stem Cells.


Journal

ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991

Informations de publication

Date de publication:
28 Sep 2022
Historique:
pubmed: 16 9 2022
medline: 1 10 2022
entrez: 15 9 2022
Statut: ppublish

Résumé

Endowing bone regeneration materials with both stem cell recruitment and osteoinduction properties is a key factor in promoting osseointegration of titanium (Ti) implants. In this study, Apt19s-grafted oxidized hyaluronic acid (OHA) was deposited onto a protein-mediated biomineralization hydroxyapatite (HAp) coating of Ti. HAp was achieved by the treatment of lysozyme and tris(2-carboxyethyl) phosphonate mixture and then soaked in calcium ion (Ca

Identifiants

pubmed: 36107718
doi: 10.1021/acsami.2c10809
doi:

Substances chimiques

Delayed-Action Preparations 0
Organophosphonates 0
Tensins 0
Vinculin 125361-02-6
APT 7320-57-2
Hyaluronic Acid 9004-61-9
Durapatite 91D9GV0Z28
Titanium D1JT611TNE
Alkaline Phosphatase EC 3.1.3.1
Muramidase EC 3.2.1.17
Calcium SY7Q814VUP
Dimaprit ZZQ699148P

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

42915-42930

Auteurs

Yujia Wei (Y)

Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.

Maohua Chen (M)

Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.

Menghuan Li (M)

School of Life Sciences, Chongqing University, Chongqing 400044, China.

Dong Wang (D)

Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.

Kaiyong Cai (K)

Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.

Zhong Luo (Z)

School of Life Sciences, Chongqing University, Chongqing 400044, China.

Yan Hu (Y)

Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, China.

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Classifications MeSH