Effects of the Seed Oil of
Adiposity
Animals
Carica
/ chemistry
Cholesterol, LDL
Diet, High-Fat
/ adverse effects
Fatty Acids
/ analysis
Fatty Acids, Monounsaturated
Hypoglycemic Agents
/ analysis
Insulin
Interleukin-6
/ analysis
Leptin
Mice
Obesity
Olive Oil
/ analysis
Resistin
Seeds
/ chemistry
Soybean Oil
/ analysis
Tumor Necrosis Factor-alpha
Brazilian fruit
dyslipidemia
oil
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
08 Oct 2022
08 Oct 2022
Historique:
received:
28
07
2022
revised:
07
09
2022
accepted:
13
09
2022
entrez:
14
10
2022
pubmed:
15
10
2022
medline:
18
10
2022
Statut:
epublish
Résumé
Studies indicate that different parts of The fatty acid composition of the oil extracted from the seeds of Papaya seed oil showed predominance of monounsaturated fatty acids in its composition. No changes were observed in the acute toxicity test. Had lower food intake in grams, and caloric intake and in the area of adipocytes without minimizing weight gain or adiposity and impacting the liver or pancreas. Reductions in total and non-HDL-c, LDL-c, and VLDL-c were also observed. The treatment had a hypoglycemic and protective effect on insulin resistance. Supplementation also resulted in higher leptin and lower insulin and cytokine resistance. Under these experimental conditions, papaya seed oil led to higher amounts of monounsaturated fatty acids and had hypocholesterolemic, hypotriglyceridemic, and hypoglycemic effects.
Sections du résumé
BACKGROUND
BACKGROUND
Studies indicate that different parts of
METHODS
METHODS
The fatty acid composition of the oil extracted from the seeds of
RESULTS
RESULTS
Papaya seed oil showed predominance of monounsaturated fatty acids in its composition. No changes were observed in the acute toxicity test. Had lower food intake in grams, and caloric intake and in the area of adipocytes without minimizing weight gain or adiposity and impacting the liver or pancreas. Reductions in total and non-HDL-c, LDL-c, and VLDL-c were also observed. The treatment had a hypoglycemic and protective effect on insulin resistance. Supplementation also resulted in higher leptin and lower insulin and cytokine resistance.
CONCLUSIONS
CONCLUSIONS
Under these experimental conditions, papaya seed oil led to higher amounts of monounsaturated fatty acids and had hypocholesterolemic, hypotriglyceridemic, and hypoglycemic effects.
Identifiants
pubmed: 36235241
pii: molecules27196705
doi: 10.3390/molecules27196705
pmc: PMC9570947
pii:
doi:
Substances chimiques
Cholesterol, LDL
0
Fatty Acids
0
Fatty Acids, Monounsaturated
0
Hypoglycemic Agents
0
Insulin
0
Interleukin-6
0
Leptin
0
Olive Oil
0
Resistin
0
Tumor Necrosis Factor-alpha
0
Soybean Oil
8001-22-7
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Coordenação de Aperfeicoamento de Pessoal de Nível Superior
ID : 001
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