Effect of an Eco-Friendly Cuminaldehyde Guanylhydrazone Disinfectant on Shiga Toxin Production and Global Transcription of
Escherichia coli
Shiga toxin-producing E. coli
disinfectant
reversible antimicrobial guanylhydrazone
transcriptome analysis
Journal
Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765
Informations de publication
Date de publication:
02 11 2022
02 11 2022
Historique:
received:
06
10
2022
revised:
24
10
2022
accepted:
30
10
2022
entrez:
10
11
2022
pubmed:
11
11
2022
medline:
15
11
2022
Statut:
epublish
Résumé
Antimicrobials have been important medicines used to treat various infections. However, some antibiotics increase the expression of Shiga toxin (Stx). Also, the pervasive use of persistent antibiotics has led to ecotoxicity and antibiotic resistance. In this study, a newly developed broad-spectrum and reversible antibiotic (guanylhydrazone disinfectant) was evaluated for its antibiotic activity and effects on Stx production and global transcription of bacteria. No Stx induction was observed in 25 Shiga toxin-producing
Identifiants
pubmed: 36356001
pii: toxins14110752
doi: 10.3390/toxins14110752
pmc: PMC9694190
pii:
doi:
Substances chimiques
cuminaldehyde
O0893NC35F
Disinfectants
0
Escherichia coli Proteins
0
Virulence Factors
0
Shiga Toxin
75757-64-1
Anti-Bacterial Agents
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Références
Appl Environ Microbiol. 2019 Jun 17;85(13):
pubmed: 31028024
Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):39-44
pubmed: 16380421
Microbiology (Reading). 2001 Sep;147(Pt 9):2493-2504
pubmed: 11535789
J Infect. 2019 Aug;79(2):75-94
pubmed: 31150744
Appl Microbiol Biotechnol. 2018 Feb;102(4):1889-1901
pubmed: 29330691
N Engl J Med. 2000 Jun 29;342(26):1930-6
pubmed: 10874060
Biology (Basel). 2013 Oct 25;2(4):1242-67
pubmed: 24833223
Bioconjug Chem. 2008 Dec;19(12):2543-8
pubmed: 19053314
J Bacteriol. 2006 Jun;188(11):3731-9
pubmed: 16707665
Rev Sci Tech. 2012 Apr;31(1):57-64
pubmed: 22849268
J Med Chem. 2016 Jul 28;59(14):6929-42
pubmed: 27353344
PLoS One. 2014 Jun 10;9(6):e99854
pubmed: 24914553
Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3812-6
pubmed: 23431179
Chem Rev. 2017 Aug 9;117(15):10358-10376
pubmed: 28640998
PLoS One. 2016 Jan 29;11(1):e0148092
pubmed: 26824247
Sci Total Environ. 2021 Apr 15;765:144264
pubmed: 33418325
J Bacteriol. 1999 Jul;181(14):4308-17
pubmed: 10400589
Zoonoses Public Health. 2019 Feb;66(1):1-13
pubmed: 30375197
PLoS One. 2019 Aug 20;14(8):e0221431
pubmed: 31430343
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12150-12155
pubmed: 27791002
J Basic Microbiol. 2013 Jan;53(1):1-8
pubmed: 22359233
Cell. 2007 Mar 23;128(6):1037-50
pubmed: 17382878
J Am Chem Soc. 2006 Dec 13;128(49):15602-3
pubmed: 17147365