NADP(H)-dependent biocatalysis without adding NADP(H).


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
03 01 2023
Historique:
entrez: 27 12 2022
pubmed: 28 12 2022
medline: 30 12 2022
Statut: ppublish

Résumé

Isocitrate dehydrogenase 1 (IDH1) naturally copurifies and crystallizes in a resting state with a molecule of its exchangeable cofactor, NADP

Identifiants

pubmed: 36574703
doi: 10.1073/pnas.2214123120
pmc: PMC9910440
doi:

Substances chimiques

NADP 53-59-8
isocitric acid 9RW6G5D4MQ
Isocitrates 0
Ferredoxin-NADP Reductase EC 1.18.1.2
Isocitrate Dehydrogenase EC 1.1.1.41

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2214123120

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P023797/1
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C8717/A18245
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 106244/Z/14/Z
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R506655/1
Pays : United Kingdom

Références

Biochemistry. 1996 Feb 27;35(8):2557-66
pubmed: 8611559
Biochem J. 2021 Feb 26;478(4):943-959
pubmed: 33565573
Nat Chem Biol. 2014 Jan;10(1):50-5
pubmed: 24240506
Nat Nanotechnol. 2016 May 5;11(5):409-20
pubmed: 27146955
Biochemistry. 2019 Dec 31;58(52):5366-5380
pubmed: 31478653
Chem Sci. 2017 Jun 1;8(6):4579-4586
pubmed: 30155220
Angew Chem Int Ed Engl. 2019 Apr 1;58(15):4948-4952
pubmed: 30633837
Protein Sci. 2021 Oct;30(10):2106-2120
pubmed: 34382711
Nat Rev Microbiol. 2018 May;16(5):277-290
pubmed: 29503457
Biochem Soc Trans. 2021 Dec 17;49(6):2561-2572
pubmed: 34854890
Cell Mol Life Sci. 2003 May;60(5):999-1006
pubmed: 12827287
Eur J Biochem. 1993 Mar 15;212(3):819-26
pubmed: 8385013
Biochemistry. 1968 Nov;7(11):4011-23
pubmed: 4301879
Phys Rev Lett. 2000 Mar 6;84(10):2064-7
pubmed: 11017210
Nat Commun. 2018 May 30;9(1):2136
pubmed: 29849027
Biochemistry. 2013 Jul 2;52(26):4563-77
pubmed: 23731180
Biol Proced Online. 2009 May 15;11:32-51
pubmed: 19495910
Semin Cell Dev Biol. 2012 Jun;23(4):370-80
pubmed: 22306135
Nature. 2009 Dec 10;462(7274):739-44
pubmed: 19935646
Philos Trans R Soc Lond B Biol Sci. 2003 Jan 29;358(1429):59-83; discussion 83-5
pubmed: 12594918
Cell Res. 2010 Nov;20(11):1188-200
pubmed: 20975740
Trends Biochem Sci. 2021 May;46(5):406-416
pubmed: 33446424
Nat Struct Biol. 1999 Sep;6(9):847-53
pubmed: 10467097
J Biol Chem. 2002 Oct 18;277(42):39548-53
pubmed: 12183470
Nat Commun. 2022 Aug 15;13(1):4785
pubmed: 35970853
Structure. 2005 Jan;13(1):43-54
pubmed: 15642260
J Biol Chem. 2002 Dec 6;277(49):46966-73
pubmed: 12351635
FEBS Lett. 2011 Nov 16;585(22):3528-32
pubmed: 22024482
J Phys Chem Lett. 2021 Jul 8;12(26):6095-6101
pubmed: 34170697
Microbiology (Reading). 2000 Apr;146 ( Pt 4):775-785
pubmed: 10784035
Commun Biol. 2021 Nov 1;4(1):1243
pubmed: 34725432
Nat Commun. 2021 Jan 12;12(1):340
pubmed: 33436601
ACS Catal. 2022 Aug 5;12(15):8811-8821
pubmed: 35966600
Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9202-7
pubmed: 12872005
J Biol Chem. 2004 Aug 6;279(32):33946-57
pubmed: 15173171
Curr Opin Chem Biol. 2020 Aug;57:122-134
pubmed: 32777735
Archaea. 2016 Nov 10;2016:9127857
pubmed: 27956891
J Mol Biol. 2002 Nov 29;324(3):519-33
pubmed: 12445786
J Chem Phys. 2020 Dec 14;153(22):225101
pubmed: 33317312
Plant Physiol. 2005 May;138(1):131-41
pubmed: 15849307
Life (Basel). 2017 Jan 17;7(1):
pubmed: 28106741
Biotechnol Bioeng. 2014 Feb;111(2):209-22
pubmed: 24142707
Biochemistry. 2016 Feb 23;55(7):1107-19
pubmed: 26848874

Auteurs

Ryan A Herold (RA)

Department of Chemistry, University of Oxford, Oxford OX1 3QR, United Kingdom.

Raphael Reinbold (R)

Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford OX1 3QY, United Kingdom.

Christopher J Schofield (CJ)

Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, Oxford OX1 3QY, United Kingdom.

Fraser A Armstrong (FA)

Department of Chemistry, University of Oxford, Oxford OX1 3QR, United Kingdom.

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Classifications MeSH