The two-electron reduced A cluster in acetyl-CoA synthase: Preparation, characteristics and mechanistic implications.
A cluster
Acetogens and methanogens
Acetyl-CoA synthase
CO dehydrogenase
Iron sulfur clusters
Nickel
Journal
Journal of inorganic biochemistry
ISSN: 1873-3344
Titre abrégé: J Inorg Biochem
Pays: United States
ID NLM: 7905788
Informations de publication
Date de publication:
03 2023
03 2023
Historique:
received:
21
09
2022
revised:
05
12
2022
accepted:
07
12
2022
pubmed:
30
12
2022
medline:
1
2
2023
entrez:
29
12
2022
Statut:
ppublish
Résumé
Acetyl-CoA synthase (ACS) is a central enzyme in the carbon and energy metabolism of certain anaerobic species of bacteria and archaea that catalyzes the direct synthesis and cleavage of the acetyl CC bond of acetyl-CoA by an unusual enzymatic mechanism of special interest for its use of organonickel intermediates. An Fe
Identifiants
pubmed: 36580832
pii: S0162-0134(22)00387-7
doi: 10.1016/j.jinorgbio.2022.112098
pii:
doi:
Substances chimiques
Acetyl Coenzyme A
72-89-9
Nitric Oxide Synthase
EC 1.14.13.39
Carbon Monoxide
7U1EE4V452
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
112098Subventions
Organisme : NIAID NIH HHS
ID : R03 AI137615
Pays : United States
Informations de copyright
Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare no competing financial conflict of interest with the contents of this article. Any opinions or assertions contained herein are the private ones of the authors and are not to be construed as official or reflecting the view of the Department of Defense or the Uniformed Services University of the Health Sciences.