Overproduction of Patchoulol in Metabolically Engineered

Komagataella phaffii metabolic engineering patchoulol sesquiterpenoids

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
01 Feb 2023
Historique:
pubmed: 23 1 2023
medline: 3 2 2023
entrez: 22 1 2023
Statut: ppublish

Résumé

Patchoulol, a plant-derived sesquiterpene compound, is widely used in perfumes, cosmetics, and pharmaceuticals. Microbial production provides a promising alternative approach for the efficient and sustainable production of patchoulol. However, there are no systematic engineering studies on

Identifiants

pubmed: 36681940
doi: 10.1021/acs.jafc.2c08228
doi:

Substances chimiques

patchouli alcohol HHH8CPR1M2
Methanol Y4S76JWI15
Sesquiterpenes 0
Carbon 7440-44-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2049-2058

Auteurs

Guangjuan Luo (G)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.

Ying Lin (Y)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.

Shuting Chen (S)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.

Ruiming Xiao (R)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.

Jiaxin Zhang (J)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.

Cheng Li (C)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

Anthony J Sinskey (AJ)

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

Lei Ye (L)

Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, P. R. China.

Shuli Liang (S)

Guangdong Key Laboratory of Fermentation and Enzyme Engineering, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Guangdong research center of Industrial enzyme and Green manufacturing technology, School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.

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Classifications MeSH