Genomic Plasticity of Acid-Tolerant Phenotypic Evolution in Acetobacter pasteurianus.

Acetobacter pasteurianus Acid-tolerant phenotype Adaptive evolution Genetic mutation Genome resequencing

Journal

Applied biochemistry and biotechnology
ISSN: 1559-0291
Titre abrégé: Appl Biochem Biotechnol
Pays: United States
ID NLM: 8208561

Informations de publication

Date de publication:
Oct 2023
Historique:
accepted: 10 01 2023
medline: 21 9 2023
pubmed: 5 2 2023
entrez: 4 2 2023
Statut: ppublish

Résumé

Acetic acid bacteria have a remarkable capacity to cope with elevated concentrations of cytotoxic acetic acid in their fermentation environment. In particular, the high-level acetate tolerance of Acetobacter pasteurianus that occurs in vinegar industrial settings must be constantly selected for. However, the improved acetic acid tolerance is rapidly lost without a selection pressure. To understand genetic and molecular biology of this acquired acetic acid tolerance in A. pasteurianus, we evolved three strains A. pasteurianus CICIM B7003, CICIM B7003-02, and ATCC 33,445 over 960 generations (4 months) in two initial acetic acids of 20 g·L

Identifiants

pubmed: 36738389
doi: 10.1007/s12010-023-04353-9
pii: 10.1007/s12010-023-04353-9
doi:

Substances chimiques

Acetic Acid Q40Q9N063P

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6003-6019

Subventions

Organisme : Young Scientists Fund
ID : 31901671
Organisme : Fundamental Research Funds for the Central Universities
ID : JUSRP121016

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Ling Gao (L)

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, People's Republic of China.

Wei Shi (W)

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, People's Republic of China.

Xiaole Xia (X)

The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, People's Republic of China. xiaolexia@jiangnan.edu.cn.

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