Mutations in
Rifampin
/ pharmacology
Peptidoglycan
/ genetics
beta-Lactams
/ pharmacology
Cefuroxime
/ pharmacology
Acetylglucosamine
Mycobacterium tuberculosis
/ genetics
Drug Resistance, Bacterial
/ genetics
Mutation
Uridine Diphosphate
DNA-Directed RNA Polymerases
/ genetics
Bacterial Proteins
/ genetics
Microbial Sensitivity Tests
Antitubercular Agents
/ pharmacology
Bacillus subtilis
Mycobacterium tuberculosis
RNA polymerases
antibiotic resistance
antibiotic synergy
metabolomics
peptidoglycan
rifampicin
β-lactams
Journal
mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231
Informations de publication
Date de publication:
25 04 2023
25 04 2023
Historique:
medline:
27
4
2023
pubmed:
14
2
2023
entrez:
13
2
2023
Statut:
ppublish
Résumé
Bacteria can adapt to stressful conditions through mutations affecting the RNA polymerase core subunits that lead to beneficial changes in transcription. In response to selection with rifampicin (RIF), mutations arise in the RIF resistance-determining region (RRDR) of
Identifiants
pubmed: 36779708
doi: 10.1128/mbio.03168-22
pmc: PMC10128067
doi:
Substances chimiques
Rifampin
VJT6J7R4TR
Peptidoglycan
0
beta-Lactams
0
Cefuroxime
O1R9FJ93ED
Acetylglucosamine
V956696549
Uridine Diphosphate
58-98-0
DNA-Directed RNA Polymerases
EC 2.7.7.6
Bacterial Proteins
0
Antitubercular Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0316822Subventions
Organisme : NIGMS NIH HHS
ID : R35 GM122461
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI162584
Pays : United States
Références
PLoS Genet. 2019 Oct 7;15(10):e1008434
pubmed: 31589605
Nucleic Acids Res. 2022 Jun 10;50(10):5739-5756
pubmed: 35639764
Appl Environ Microbiol. 1986 Nov;52(5):1112-6
pubmed: 3098166
Am J Respir Crit Care Med. 2022 May 15;205(10):1228-1235
pubmed: 35258443
Nature. 2004 Mar 18;428(6980):281-6
pubmed: 15029187
J Biol Chem. 2016 Jul 1;291(27):14248-14256
pubmed: 27226566
Future Microbiol. 2017 Jul;12:753-765
pubmed: 28343421
Genome Biol Evol. 2022 Sep 6;14(9):
pubmed: 35876137
Front Microbiol. 2017 Feb 13;8:178
pubmed: 28243227
J Clin Tuberc Other Mycobact Dis. 2017 Jun 20;8:19-25
pubmed: 31723707
J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18
pubmed: 6440886
PLoS Pathog. 2016 Nov 2;12(11):e1006001
pubmed: 27806131
Diagn Microbiol Infect Dis. 1993 May-Jun;16(4):343-9
pubmed: 8495592
PLoS Negl Trop Dis. 2019 Jan 28;13(1):e0007126
pubmed: 30689630
J Bacteriol. 2011 Jul;193(14):3525-36
pubmed: 21602348
Appl Environ Microbiol. 2008 Nov;74(21):6649-55
pubmed: 18806005
J Bacteriol. 2008 Feb;190(3):807-14
pubmed: 17644585
Antimicrob Agents Chemother. 1995 Aug;39(8):1815-9
pubmed: 7486924
J Antimicrob Chemother. 2018 Apr 1;73(4):973-980
pubmed: 29253242
Elife. 2020 Sep 08;9:
pubmed: 32897856
Sci Rep. 2016 Sep 28;6:34293
pubmed: 27678056
Front Microbiol. 2018 Feb 14;9:192
pubmed: 29491852
Front Med (Lausanne). 2021 Oct 05;8:723667
pubmed: 34676224
Infect Drug Resist. 2021 Oct 05;14:4119-4128
pubmed: 34675557
Antimicrob Agents Chemother. 2013 Oct;57(10):4861-71
pubmed: 23877693
J Antimicrob Chemother. 2003 Jul;52(1):1
pubmed: 12805255
J Bacteriol. 2002 Sep;184(17):4936-40
pubmed: 12169622
Tuber Lung Dis. 1998;79(1):3-29
pubmed: 10645439
Appl Environ Microbiol. 2022 Mar 8;88(5):e0242221
pubmed: 35258334
Curr Opin Microbiol. 2015 Oct;27:1-9
pubmed: 26042389
ACS Infect Dis. 2022 Mar 11;8(3):557-573
pubmed: 35192346
Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19646-19651
pubmed: 31501323
Appl Environ Microbiol. 2015 Jan;81(1):17-30
pubmed: 25304508
Mol Microbiol. 2017 Mar;103(6):1034-1045
pubmed: 28009073
Sci Rep. 2020 Sep 29;10(1):15938
pubmed: 32994436
J Biol Chem. 1999 Apr 16;274(16):11110-4
pubmed: 10196195
Cell Chem Biol. 2022 Feb 17;29(2):276-286.e4
pubmed: 34990601
PLoS Genet. 2018 Sep 24;14(9):e1007689
pubmed: 30248093
Methods Mol Biol. 2021;2314:579-593
pubmed: 34235671
Genes Dev. 2007 Dec 15;21(24):3356-68
pubmed: 18079181
Comput Struct Biotechnol J. 2015 Sep 25;13:504-13
pubmed: 26949479
J Bacteriol. 2005 Apr;187(8):2783-92
pubmed: 15805525
Infect Drug Resist. 2018 Aug 07;11:1083-1095
pubmed: 30122965
Antimicrob Agents Chemother. 2002 Feb;46(2):511-3
pubmed: 11796364
Antimicrob Agents Chemother. 2015 Oct;59(10):6561-7
pubmed: 26259792
Antimicrob Agents Chemother. 2004 Apr;48(4):1289-94
pubmed: 15047531
Infect Immun. 2014 Oct;82(10):4104-17
pubmed: 25047842
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14918-23
pubmed: 18815368
J Mol Biol. 1988 Jul 5;202(1):45-58
pubmed: 3050121
Crit Rev Biochem Mol Biol. 2007 Sep-Oct;42(5):373-97
pubmed: 17917873
Nat Microbiol. 2021 Nov;6(11):1410-1423
pubmed: 34697460
Mol Microbiol. 2014 Apr;92(1):100-15
pubmed: 24673833
Emerg Microbes Infect. 2014 Mar;3(3):e17
pubmed: 26038512
J Biol Chem. 2001 Jan 19;276(3):1772-9
pubmed: 11038353
Ann Clin Microbiol Antimicrob. 2012 Jun 20;11:18
pubmed: 22716026
Cell Syst. 2017 Mar 22;4(3):291-305.e7
pubmed: 28189581
Lancet Microbe. 2021 Oct;2(10):e545-e554
pubmed: 34632433
J Antimicrob Chemother. 2009 Aug;64(2):259-62
pubmed: 19520715
Cold Spring Harb Perspect Med. 2015 Jan 08;5(5):a017822
pubmed: 25573773
Antimicrob Agents Chemother. 2014;58(3):1757-62
pubmed: 24395223
Antimicrob Agents Chemother. 2012 Dec;56(12):6250-5
pubmed: 23006749
Mol Biol Evol. 2015 May;32(5):1175-85
pubmed: 25618457
Nature. 1970 Aug 29;227(5261):906-9
pubmed: 4988656
PLoS Pathog. 2020 Jul 24;16(7):e1008672
pubmed: 32706832
Mol Cell. 2021 May 20;81(10):2201-2215.e9
pubmed: 34019789
ACS Chem Biol. 2020 May 15;15(5):1242-1251
pubmed: 32155044
Chem Biol. 2005 Nov;12(11):1221-6
pubmed: 16298301
Antimicrob Agents Chemother. 2010 Dec;54(12):5222-33
pubmed: 20837752
Cold Spring Harb Perspect Med. 2017 Feb 1;7(2):
pubmed: 28062557
J Bacteriol. 2016 May 13;198(11):1610-1620
pubmed: 27002132
Nature. 2001 Oct 25;413(6858):814-21
pubmed: 11677599
Appl Environ Microbiol. 2021 Oct 28;87(22):e0123721
pubmed: 34495706
Front Microbiol. 2018 Mar 19;9:494
pubmed: 29616007