FERM domains recruit ample PI(4,5)P


Journal

Biophysical journal
ISSN: 1542-0086
Titre abrégé: Biophys J
Pays: United States
ID NLM: 0370626

Informations de publication

Date de publication:
04 04 2023
Historique:
received: 29 10 2022
revised: 26 01 2023
accepted: 18 02 2023
pmc-release: 04 04 2024
medline: 7 4 2023
pubmed: 24 2 2023
entrez: 23 2 2023
Statut: ppublish

Résumé

The four-point-one ezrin-radixin-moesin homology (FERM) protein domain is a multifunctional protein-lipid binding site, constituting an integral part of numerous membrane-associated proteins. Its interaction with the lipid phosphatidylinositol-4,5-bisphosphate (PIP

Identifiants

pubmed: 36814382
pii: S0006-3495(23)00133-9
doi: 10.1016/j.bpj.2023.02.027
pmc: PMC10111351
pii:
doi:

Substances chimiques

Lipid Bilayers 0
Focal Adhesion Protein-Tyrosine Kinases EC 2.7.10.2
Phosphatidylinositol 4,5-Diphosphate 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1325-1333

Informations de copyright

Copyright © 2023 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

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Auteurs

Thomas Ehret (T)

Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.

Tim Heißenberg (T)

Institute of Organic and Biomolecular Chemistry, University of Göttingen, Göttingen, Germany; Max Planck School Matter to Life, Heidelberg and Göttingen, Germany.

Svenja de Buhr (S)

Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.

Camilo Aponte-Santamaría (C)

Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.

Claudia Steinem (C)

Institute of Organic and Biomolecular Chemistry, University of Göttingen, Göttingen, Germany; Max Planck School Matter to Life, Heidelberg and Göttingen, Germany. Electronic address: csteine@gwdg.de.

Frauke Gräter (F)

Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany; Max Planck School Matter to Life, Heidelberg and Göttingen, Germany; Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany. Electronic address: frauke.graeter@h-its.org.

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Classifications MeSH