High-Density Guide RNA Tiling and Machine Learning for Designing CRISPR Interference in

CRISPR-Cas Systems / genetics Synechococcus / genetics Clustered Regularly Interspaced Short Palindromic Repeats / genetics DNA RNA
CRISPRi Synechococcus Synechococcus sp. PCC 7002 cyanobacteria gRNA design machine learning

Journal

ACS synthetic biology
ISSN: 2161-5063
Titre abrégé: ACS Synth Biol
Pays: United States
ID NLM: 101575075

Informations de publication

Date de publication:
21 04 2023
Historique:
medline: 24 4 2023
pubmed: 10 3 2023
entrez: 9 3 2023
Statut: ppublish

Résumé

While CRISPRi was previously established in

Identifiants

DOI: 10.1021/acssynbio.2c00653 PMID: 36893454
pubmed: 36893454
doi: 10.1021/acssynbio.2c00653
doi:

Substances chimiques

DNA 9007-49-2
RNA 63231-63-0

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1175-1186

Auteurs

Tessa Dallo (T)

Molecular and Microbiology, Sandia National Laboratories, P.O. Box 5800, MS 1413, Albuquerque, New Mexico 87185, United States.

Raga Krishnakumar (R)

Systems Biology, Sandia National Laboratories, P.O. Box 969, MS 9292, Livermore, California 94551, United States.

Stephanie D Kolker (SD)

Molecular and Microbiology, Sandia National Laboratories, P.O. Box 5800, MS 1413, Albuquerque, New Mexico 87185, United States.

Anne M Ruffing (AM)

Molecular and Microbiology, Sandia National Laboratories, P.O. Box 5800, MS 1413, Albuquerque, New Mexico 87185, United States.
ORCID: 0000-0002-6058-1973

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Systèmes CRISPR-Cas › High-Density Guide RNA Tiling and Machine...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Bactéries à Gram négatif photosynthétiques › Cyanobactéries › Synechococcus › High-Density Guide RNA Tiling and Machine...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Séquences répétées en tandem › Clustered regularly interspaced short palindromic repeats › High-Density Guide RNA Tiling and Machine...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › High-Density Guide RNA Tiling and Machine...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › High-Density Guide RNA Tiling and Machine...