Adaptive responses of yeast strains tolerant to acidic pH, acetate, and supraoptimal temperature.

Saccharomyces cerevisiae / metabolism Temperature Saccharomyces cerevisiae Proteins / genetics Acetic Acid / metabolism Glucose / metabolism Hydrogen-Ion Concentration Membrane Proteins / metabolism Protein Phosphatase 1 / metabolism Trans-Activators / metabolism Vacuolar Proton-Translocating ATPases / metabolism
Adaptive cellular responses Adaptive laboratory evolution Genome-scale analysis Saccharomyces cerevisiae Thermo-acidic tolerance

Journal

Applied microbiology and biotechnology
ISSN: 1432-0614
Titre abrégé: Appl Microbiol Biotechnol
Pays: Germany
ID NLM: 8406612

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 17 02 2023
accepted: 23 04 2023
revised: 20 04 2023
medline: 5 6 2023
pubmed: 14 5 2023
entrez: 13 5 2023
Statut: ppublish

Résumé

Ethanol fermentations can be prematurely halted as Saccharomyces cerevisiae faces adverse conditions, such as acidic pH, presence of acetic acid, and supraoptimal temperatures. The knowledge on yeast responses to these conditions is essential to endowing a tolerant phenotype to another strain by targeted genetic manipulation. In this study, physiological and whole-genome analyses were conducted to obtain insights on molecular responses which potentially render yeast tolerant towards thermoacidic conditions. To this end, we used thermotolerant TTY23, acid tolerant AT22, and thermo-acid tolerant TAT12 strains previously generated by adaptive laboratory evolution (ALE) experiments. The results showed an increase in thermoacidic profiles in the tolerant strains. The whole-genome sequence revealed the importance of genes related to: H

Identifiants

DOI: 10.1007/s00253-023-12556-7 PMID: 37178307 PMC: PMC10238323
pubmed: 37178307
doi: 10.1007/s00253-023-12556-7
pii: 10.1007/s00253-023-12556-7
pmc: PMC10238323
doi:

Substances chimiques

Saccharomyces cerevisiae Proteins 0
Acetic Acid Q40Q9N063P
Glucose IY9XDZ35W2
ATO2 protein, S cerevisiae 0
Membrane Proteins 0
REG1 protein, S cerevisiae EC 3.1.3.16
Protein Phosphatase 1 EC 3.1.3.16
BAS1 protein, S cerevisiae 0
Trans-Activators 0
VMA2 protein, S cerevisiae EC 3.6.1.-
Vacuolar Proton-Translocating ATPases EC 3.6.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4051-4068

Informations de copyright

© 2023. The Author(s).

Références

Metab Eng. 2017 Jan;39:19-28
pubmed: 27815194
Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):6746-50
pubmed: 1495962
Microbiology (Reading). 1994 Nov;140 ( Pt 11):3031-8
pubmed: 7812443
Mol Biol Cell. 2004 Feb;15(2):706-20
pubmed: 14617816
Adv Microb Physiol. 1984;25:195-251
pubmed: 6398621
Nucleic Acids Res. 2012 Jan;40(Database issue):D169-79
pubmed: 22102575
BMC Cell Biol. 2010 Nov 25;11:92
pubmed: 21108829
Mol Ecol. 2012 May;21(9):2058-77
pubmed: 22332770
Yeast. 1993 Oct;9(10):1075-84
pubmed: 8256514
Yeast. 2021 Jul;38(7):391-400
pubmed: 34000094
Genetics. 2003 Nov;165(3):1017-29
pubmed: 14668361
Microbiol Mol Biol Rev. 1998 Jun;62(2):334-61
pubmed: 9618445
Mol Biol Cell. 2016 Aug 1;27(15):2505-14
pubmed: 27307591
Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):957-970
pubmed: 30796938
Biochim Biophys Acta. 2011 Oct;1810(10):933-44
pubmed: 21421024
J Biol Chem. 1994 Mar 25;269(12):9155-65
pubmed: 8132653
J Biol Chem. 2018 Feb 16;293(7):2318-2329
pubmed: 29284676
Biotechnol Bioeng. 1989 Apr 20;33(10):1350-2
pubmed: 18587871
Indian J Microbiol. 2011 Jun;51(2):153-8
pubmed: 22654157
Nature. 1986 Feb 20-26;319(6055):689-93
pubmed: 3005867
Biotechnol Biofuels. 2019 Dec 27;12:298
pubmed: 31890026
Mol Cell Biol. 2002 Apr;22(8):2642-9
pubmed: 11909958
Sci Rep. 2017 Feb 17;7:42659
pubmed: 28209995
Microbiology (Reading). 2009 Jan;155(Pt 1):268-278
pubmed: 19118367
PLoS Genet. 2018 May 25;14(5):e1007396
pubmed: 29799840
Nature. 2012 Dec 13;492(7428):261-5
pubmed: 23172144
Mol Biol Cell. 1995 Jan;6(1):59-70
pubmed: 7749195
Appl Microbiol Biotechnol. 2022 Jan;106(1):383-399
pubmed: 34913993
Cell Stress Chaperones. 1997 Mar;2(1):12-24
pubmed: 9250391
Appl Microbiol Biotechnol. 2017 Jan;101(1):229-239
pubmed: 27730338
J Gen Microbiol. 1991 Jul;137(7):1701-8
pubmed: 1835495
J Biol Chem. 2021 Nov;297(5):101050
pubmed: 34571008
J Biol Chem. 2004 Aug 6;279(32):33653-61
pubmed: 15161905
Cell Syst. 2018 Feb 28;6(2):192-205.e3
pubmed: 29361465
J Biol Chem. 1998 Dec 11;273(50):33360-6
pubmed: 9837911
J Biol Chem. 2004 Jul 30;279(31):32093-9
pubmed: 15145950
PLoS One. 2014 Mar 05;9(3):e90581
pubmed: 24599324
J Biol Chem. 2001 Aug 10;276(32):29613-6
pubmed: 11404364
Microbiol Mol Biol Rev. 2006 Mar;70(1):177-91
pubmed: 16524922
J Biol Chem. 2008 Jul 18;283(29):20309-19
pubmed: 18502746
Proteomics. 2009 Feb;9(3):720-32
pubmed: 19137548
Appl Microbiol Biotechnol. 2015 Aug;99(15):6391-403
pubmed: 26062532
Antonie Van Leeuwenhoek. 2013 Dec;104(6):1083-95
pubmed: 24062068
Arch Microbiol. 1996 Nov;166(5):315-20
pubmed: 8929277
Microbiol Mol Biol Rev. 2012 Jun;76(2):115-58
pubmed: 22688810
Appl Environ Microbiol. 2012 Dec;78(23):8377-87
pubmed: 23001666
Elife. 2020 Aug 07;9:
pubmed: 32762843
Genome Res. 1998 Mar;8(3):186-94
pubmed: 9521922
Elife. 2022 Apr 19;11:
pubmed: 35438635
Mol Cell Biol. 1997 Jun;17(6):3220-8
pubmed: 9154821
Front Microbiol. 2013 Feb 20;4:33
pubmed: 23430312
Appl Microbiol Biotechnol. 2010 May;86(6):1915-24
pubmed: 20309542
J Biol Chem. 1998 Feb 6;273(6):3148-51
pubmed: 9452424
Sci Rep. 2016 May 27;6:27003
pubmed: 27229477
Genetics. 1986 May;113(1):35-43
pubmed: 3519363
Nat Rev Genet. 2007 Nov;8(11):835-44
pubmed: 17909538
Mol Biol Cell. 2000 Dec;11(12):4241-57
pubmed: 11102521
Science. 1996 Oct 25;274(5287):546, 563-7
pubmed: 8849441
J Bacteriol. 1999 Apr;181(8):2620-3
pubmed: 10198029
Yeast. 1992 Jul;8(7):501-17
pubmed: 1523884
FEMS Yeast Res. 2012 Jan 18;12(3):359-374
pubmed: 22257278
Microb Cell Fact. 2010 Oct 25;9:79
pubmed: 20973990
Genetics. 2012 Sep;192(1):73-105
pubmed: 22964838
Genome Res. 2011 Jul;21(7):1131-8
pubmed: 21422276
Gene. 2005 Jul 18;354:93-8
pubmed: 15894436
Microbiology (Reading). 1994 Aug;140 ( Pt 8):1881-90
pubmed: 7921241
FEBS J. 2014 Apr;281(7):1901-17
pubmed: 24529170
Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14315-22
pubmed: 15353587
Biochem Biophys Res Commun. 2005 Nov 11;337(1):95-103
pubmed: 16176797
Appl Environ Microbiol. 2015 Nov;81(22):7813-21
pubmed: 26341199
Mol Biol Cell. 2000 Jul;11(7):2335-47
pubmed: 10888672
Mol Gen Genet. 1991 Apr;226(1-2):224-32
pubmed: 1903502
Sci Rep. 2015 Aug 18;5:13241
pubmed: 26283179
Genetics. 1992 Jul;131(3):551-8
pubmed: 1628805
Methods Mol Biol. 2018;1706:223-232
pubmed: 29423801
Biotechnol Bioeng. 2019 Oct;116(10):2587-2597
pubmed: 31282999
J Gen Microbiol. 1970 Nov;64(1):91-9
pubmed: 5516609
mBio. 2015 Jul 21;6(4):e00431
pubmed: 26199325

Auteurs

Prisciluis Caheri Salas-Navarrete (PC)

Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Col. Chamilpa, Cuernavaca, 62209, Morelos, México.

Paul Rosas-Santiago (P)

Departamento de Biología Molecular de Plantas, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Col. Chamilpa, Cuernavaca, 62210, Morelos, México.

Ramón Suárez-Rodríguez (R)

Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Col. Chamilpa, Cuernavaca, 62209, Morelos, México.

Alfredo Martínez (A)

Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Col. Chamilpa, Cuernavaca, 62210, Morelos, México.

Luis Caspeta (L)

Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Av. Universidad 2001, Col. Chamilpa, Cuernavaca, 62210, Morelos, México. luis.caspeta@ibt.unam.mx.
ORCID: 0000-0003-4622-5179

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Levures › Saccharomyces › Saccharomyces cerevisiae › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Température › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › Protéines de Saccharomyces cerevisiae › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Lipides › Acides gras › Acides gras volatils › Acétates › Acide acétique › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Phosphoprotein Phosphatases › Protein Phosphatase 1 › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales régulatrices ou accessoires › Transactivateurs › Adaptive responses of yeast strains tolerant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs de cations › Pompes à protons › Proton-Translocating ATPases › Vacuolar Proton-Translocating ATPases › Adaptive responses of yeast strains tolerant...