Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry.

Crystallography, X-Ray DNA, B-Form DNA / chemistry Mass Spectrometry

Journal

Dalton transactions (Cambridge, England : 2003)
ISSN: 1477-9234
Titre abrégé: Dalton Trans
Pays: England
ID NLM: 101176026

Informations de publication

Date de publication:
30 May 2023
Historique:
medline: 31 5 2023
pubmed: 18 5 2023
entrez: 18 5 2023
Statut: epublish

Résumé

The reaction of the cytotoxic compound dirhodium tetraacetate with a B-DNA double helical dodecamer was studied by X-ray crystallography and mass spectrometry. The structure of the dirhodium/DNA adduct reveals a dimetallic center binding to an adenine

Identifiants

DOI: 10.1039/d3dt00320e PMID: 37199244
pubmed: 37199244
doi: 10.1039/d3dt00320e
doi:

Substances chimiques

dirhodium tetraacetate NK3058Z56X
DNA, B-Form 0
DNA 9007-49-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6992-6996

Auteurs

Gabriella Tito (G)

Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo via Cintia, I-80126 Napoli, Italy. antonello.merlino@unina.it.
ORCID: 0000-0001-5682-3100

Romualdo Troisi (R)

Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo via Cintia, I-80126 Napoli, Italy. antonello.merlino@unina.it.
ORCID: 0000-0002-3484-3589

Giarita Ferraro (G)

Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo via Cintia, I-80126 Napoli, Italy. antonello.merlino@unina.it.
ORCID: 0000-0001-9385-2429

Andrea Geri (A)

Department of Chemistry "U. Schiff", University of Florence, via della Lastruccia 3, 50019 Sesto Fiorentino, Italy.

Lara Massai (L)

Department of Chemistry "U. Schiff", University of Florence, via della Lastruccia 3, 50019 Sesto Fiorentino, Italy.
ORCID: 0000-0003-0765-1802

Luigi Messori (L)

Department of Chemistry "U. Schiff", University of Florence, via della Lastruccia 3, 50019 Sesto Fiorentino, Italy.
ORCID: 0000-0002-9490-8014

Filomena Sica (F)

Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo via Cintia, I-80126 Napoli, Italy. antonello.merlino@unina.it.
ORCID: 0000-0003-4501-4476

Antonello Merlino (A)

Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo via Cintia, I-80126 Napoli, Italy. antonello.merlino@unina.it.
ORCID: 0000-0002-1045-7720

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Dirhodium tetraacetate binding to a B-DNA...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › Forme B de l'ADN › Dirhodium tetraacetate binding to a B-DNA...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Dirhodium tetraacetate binding to a B-DNA...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Dirhodium tetraacetate binding to a B-DNA...