Gene editing and scalable functional genomic screening in

Leishmania / genetics CRISPR-Cas Systems Gene Editing Genomics Cytosine
CRISPR/Cas9 LeishBASEedit Leishmania cytosine base editor genetics genomics infectious disease loss-of-function screening microbiology

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
24 05 2023
Historique:
received: 15 12 2022
accepted: 28 04 2023
medline: 26 5 2023
pubmed: 24 5 2023
entrez: 24 5 2023
Statut: epublish

Résumé

CRISPR/Cas9 gene editing has revolutionised loss-of-function experiments in

Identifiants

DOI: 10.7554/eLife.85605 PMID: 37222701 PMC: PMC10208639
pubmed: 37222701
doi: 10.7554/eLife.85605
pii: 85605
pmc: PMC10208639
doi:
pii:

Substances chimiques

Cytosine 8J337D1HZY

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023, Engstler and Beneke.

Déclaration de conflit d'intérêts

ME, TB No competing interests declared

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Auteurs

Markus Engstler (M)

Department of Cell and Developmental Biology, Biocentre, University of Würzburg, Wuerzburg, Germany.

Tom Beneke (T)

Department of Cell and Developmental Biology, Biocentre, University of Würzburg, Wuerzburg, Germany.
ORCID: 0000-0001-9117-2649

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Euglénozoaires › Kinetoplastida › Trypanosomatina › Leishmania › Gene editing and scalable functional genomic...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Systèmes CRISPR-Cas › Gene editing and scalable functional genomic...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Édition de gène › Gene editing and scalable functional genomic...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Gene editing and scalable functional genomic...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Pyrimidinones › Cytosine › Gene editing and scalable functional genomic...