D-amino acids signal a stress-dependent run-away response in Vibrio cholerae.
Journal
Nature microbiology
ISSN: 2058-5276
Titre abrégé: Nat Microbiol
Pays: England
ID NLM: 101674869
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
03
01
2023
accepted:
31
05
2023
medline:
2
8
2023
pubmed:
27
6
2023
entrez:
26
6
2023
Statut:
ppublish
Résumé
To explore favourable niches while avoiding threats, many bacteria use a chemotaxis navigation system. Despite decades of studies on chemotaxis, most signals and sensory proteins are still unknown. Many bacterial species release D-amino acids to the environment; however, their function remains largely unrecognized. Here we reveal that D-arginine and D-lysine are chemotactic repellent signals for the cholera pathogen Vibrio cholerae. These D-amino acids are sensed by a single chemoreceptor MCP
Identifiants
pubmed: 37365341
doi: 10.1038/s41564-023-01419-6
pii: 10.1038/s41564-023-01419-6
pmc: PMC10390336
doi:
Substances chimiques
Amino Acids
0
Lysine
K3Z4F929H6
Bacterial Proteins
0
Arginine
94ZLA3W45F
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1549-1560Informations de copyright
© 2023. The Author(s).
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