Intensity-Based Camera Setup for Refractometric and Biomolecular Sensing with a Photonic Crystal Microfluidic Chip.
biochip
label-free
microfluidics
photonic crystal slab
point-of-care
Journal
Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191
Informations de publication
Date de publication:
27 Jun 2023
27 Jun 2023
Historique:
received:
04
05
2023
revised:
21
06
2023
accepted:
25
06
2023
medline:
31
7
2023
pubmed:
28
7
2023
entrez:
28
7
2023
Statut:
epublish
Résumé
Label-free sensing is a promising approach for point-of-care testing devices. Among optical transducers, photonic crystal slabs (PCSs) have positioned themselves as an inexpensive yet versatile platform for label-free biosensing. A spectral resonance shift is observed upon biomolecular binding to the functionalized surface. Commonly, a PCS is read out by a spectrometer. Alternatively, the spectral shift may be translated into an intensity change by tailoring the system response. Intensity-based camera setups (IBCS) are of interest as they mitigate the need for postprocessing, enable spatial sampling, and have moderate hardware requirements. However, they exhibit modest performance compared with spectrometric approaches. Here, we show an increase of the sensitivity and limit of detection (LOD) of an IBCS by employing a sharp-edged cut-off filter to optimize the system response. We report an increase of the LOD from (7.1 ± 1.3) × 10
Identifiants
pubmed: 37504086
pii: bios13070687
doi: 10.3390/bios13070687
pmc: PMC10377058
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : German Federal Ministry of Economic Affairs and Climate Action (BMWK)
ID : ZF4558806SB9
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Appl Opt. 1993 May 10;32(14):2606-13
pubmed: 20820422
Opt Lett. 2016 Nov 15;41(22):5302-5305
pubmed: 27842118
Talanta. 2011 Oct 30;86:377-83
pubmed: 22063554
Nat Biotechnol. 2008 Dec;26(12):1373-8
pubmed: 19029914
Sci Rep. 2019 Jun 19;9(1):8745
pubmed: 31217478
Lab Chip. 2006 Jul;6(7):871-80
pubmed: 16804591
Opt Express. 2010 Dec 20;18(26):27930-7
pubmed: 21197066
Clin Chim Acta. 2006 Aug;370(1-2):191-5
pubmed: 16545790
Opt Express. 2015 Jun 29;23(13):16529-39
pubmed: 26191664
Nanomaterials (Basel). 2022 May 20;12(10):
pubmed: 35630973
Biosens Bioelectron. 2019 Feb 1;126:315-323
pubmed: 30448719
Sensors (Basel). 2021 Jan 07;21(2):
pubmed: 33430392
Lab Chip. 2014 Jul 7;14(13):2287-92
pubmed: 24825250
Opt Express. 2017 May 01;25(9):10536-10545
pubmed: 28468426
Biomed Opt Express. 2022 Nov 08;13(12):6300-6316
pubmed: 36589587
Anal Chem. 2010 Jun 15;82(12):5211-8
pubmed: 20486666
Opt Quantum Electron. 2017;49(3):107
pubmed: 32214612
J Colloid Interface Sci. 2003 Dec 1;268(1):1-11
pubmed: 14611765
Electrophoresis. 2003 Nov;24(21):3563-76
pubmed: 14613181
Sci Rep. 2016 Apr 13;6:24385
pubmed: 27072067
Sci Adv. 2017 Mar 22;3(3):e1501645
pubmed: 28345028
Biomaterials. 2002 Sep;23(17):3699-710
pubmed: 12109695
Shock. 2021 Nov 1;56(5):682-690
pubmed: 33660669
Curr Opin Environ Sci Health. 2019 Aug;10:38-46
pubmed: 31903443
Opt Express. 2010 Oct 25;18(22):22702-14
pubmed: 21164609
Opt Express. 2020 Oct 26;28(22):32239-32248
pubmed: 33114915
Opt Express. 2023 Jan 30;31(3):4319-4333
pubmed: 36785403
Opt Lett. 2016 Apr 1;41(7):1447-50
pubmed: 27192258
Expert Rev Mol Diagn. 2019 Jan;19(1):71-81
pubmed: 30513011
Bioengineering (Basel). 2021 Jul 03;8(7):
pubmed: 34356201
Lab Chip. 2011 Mar 7;11(5):845-50
pubmed: 21152509
Biosens Bioelectron. 2020 Apr 1;153:112047
pubmed: 31999559
Biomed Opt Express. 2023 Apr 26;14(5):2293-2310
pubmed: 37206136
J Med Virol. 2020 Sep;92(9):1518-1524
pubmed: 32104917
Biomed Opt Express. 2015 Sep 01;6(10):3724-36
pubmed: 26504624
ACS Sens. 2020 Nov 25;5(11):3474-3482
pubmed: 33108735
Nanoscale. 2018 Jul 9;10(26):12797-12804
pubmed: 29947396
Opt Lett. 2023 Apr 15;48(8):2010-2013
pubmed: 37058629
Opt Express. 2007 Apr 16;15(8):4977-93
pubmed: 19532747
Nanomaterials (Basel). 2019 Jun 01;9(6):
pubmed: 31159384
J Anal Methods Chem. 2013;2013:581093
pubmed: 24490106
Biomed Opt Express. 2021 Jun 21;12(7):4265-4275
pubmed: 34457413
ACS Photonics. 2022 May 18;9(5):1757-1763
pubmed: 35607641
Sci Rep. 2017 Aug 8;7(1):7607
pubmed: 28790427
Opt Express. 2014 Jan 13;22(1):916-24
pubmed: 24515051
Science. 1989 Jan 6;243(4887):85-8
pubmed: 2911722
Sensors (Basel). 2021 Feb 05;21(4):
pubmed: 33562639
Opt Express. 2010 Aug 30;18(18):19120-8
pubmed: 20940807
Sci Rep. 2021 Jun 22;11(1):13091
pubmed: 34158570