Protein phosphatase 2A: a high-value target of virulence factors.

Virulence Factors / metabolism Protein Phosphatase 2 / metabolism Virulence Plants Protein Processing, Post-Translational
PP2A effector pathogen virulence factor

Journal

Trends in parasitology
ISSN: 1471-5007
Titre abrégé: Trends Parasitol
Pays: England
ID NLM: 100966034

Informations de publication

Date de publication:
10 2023
Historique:
received: 27 07 2023
accepted: 31 07 2023
medline: 18 9 2023
pubmed: 15 8 2023
entrez: 14 8 2023
Statut: ppublish

Résumé

Pathogen-encoded virulence factors perturb host physiology and immune function to promote infection. Reinforcing the concept that protein phosphatase 2A (PP2A) is convergently targeted by virulence factors from diverse pathogens, Li et al. demonstrate that PP2A is coopted by members of a modular family of effector proteins from a plant-pathogenic oomycete.

Identifiants

DOI: 10.1016/j.pt.2023.07.010 PMID: 37580205
pubmed: 37580205
pii: S1471-4922(23)00191-5
doi: 10.1016/j.pt.2023.07.010
pii:
doi:

Substances chimiques

Virulence Factors 0
Protein Phosphatase 2 EC 3.1.3.16

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

803-805

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Reid Gohmann (R)

Department of Horticulture and Crop Science, The Ohio State University, Columbus, OH 43210, USA; Molecular, Cellular, and Developmental Biology Program, Ohio State University, Columbus, OH 43210, USA.

David Mackey (D)

Department of Horticulture and Crop Science, The Ohio State University, Columbus, OH 43210, USA; Department of Molecular Genetics, The Ohio State University, Columbus, OH 43210, USA; Center for Applied Plant Sciences, The Ohio State University, Columbus, OH 43210, USA. Electronic address: mackey.86@osu.edu.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Facteurs de virulence › Protein phosphatase 2A: a high-value target of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Phosphoprotein Phosphatases › Protein Phosphatase 2 › Protein phosphatase 2A: a high-value target of...
questionsmedicales.fr › Phénomènes microbiologiques › Virulence › Protein phosphatase 2A: a high-value target of...
questionsmedicales.fr › Eucaryotes › Plantes › Protein phosphatase 2A: a high-value target of...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Modification traductionnelle des protéines › Maturation post-traductionnelle des protéines › Protein phosphatase 2A: a high-value target of...