Direct interaction between the transmembrane helices stabilize cytochrome P450 2B4 and cytochrome b5 redox complex.

Cytochromes b5 / chemistry Aryl Hydrocarbon Hydroxylases / chemistry Cytochrome P450 Family 2 / metabolism Oxidation-Reduction
Cytochrome-P450 Cytochrome-b5 Lipid bilayer Redox complex Structure Transmembrane-transmebrane

Journal

Biophysical chemistry
ISSN: 1873-4200
Titre abrégé: Biophys Chem
Pays: Netherlands
ID NLM: 0403171

Informations de publication

Date de publication:
10 2023
Historique:
received: 12 06 2023
revised: 06 08 2023
accepted: 07 08 2023
medline: 6 9 2023
pubmed: 17 8 2023
entrez: 16 8 2023
Statut: ppublish

Résumé

The catalytic activity of cytochrome P450 2B4 (CYP2B4) is moderated by its cognate redox partner cytochrome b5 (Cyt-b

Identifiants

DOI: 10.1016/j.bpc.2023.107092 PMID: 37586236
pubmed: 37586236
pii: S0301-4622(23)00143-6
doi: 10.1016/j.bpc.2023.107092
pii:
doi:

Substances chimiques

cytochrome P-450 CYP2B4 (rabbit) EC 1.14.14.1
Cytochromes b5 9035-39-6
Aryl Hydrocarbon Hydroxylases EC 1.14.14.1
Cytochrome P450 Family 2 EC 1.14.14.1

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

107092

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM139572
Pays : United States

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Bikash R Sahoo (BR)

Biophysics Program, Department of Chemistry, Macromolecular Science and Engineering, Biomedical Engineering, Michigan Neuroscience Institute, The University of Michigan, Ann Arbor, MI 48109-1055, USA. Electronic address: bsahoo@umich.edu.

Ayyalusamy Ramamoorthy (A)

Biophysics Program, Department of Chemistry, Macromolecular Science and Engineering, Biomedical Engineering, Michigan Neuroscience Institute, The University of Michigan, Ann Arbor, MI 48109-1055, USA. Electronic address: ramamoor@umich.edu.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochromes de type b › Cytochromes b5 › Direct interaction between the transmembrane...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › Aryl hydrocarbon hydroxylases › Direct interaction between the transmembrane...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › Famille-2 de cytochromes P450 › Direct interaction between the transmembrane...
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › Direct interaction between the transmembrane...