Phytochemical investigation of aerial parts of Woodsia ilvensis and its plasmin-inhibitory activity in vitro.
Maleimide N-glycosides
Plasmin-inhibitory flavonoids
Stilbenoid glycoside
Woodsia ilvensis
Woodsiaceae
Journal
Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
22
02
2023
revised:
12
08
2023
accepted:
14
08
2023
medline:
4
10
2023
pubmed:
21
8
2023
entrez:
20
8
2023
Statut:
ppublish
Résumé
The fern plant Woodsia ilvensis (L.) R. Br. belongs to the Woodsiaceae family and its leaves are used to treat diarrhea, soft-tissue injuries, and external injuries. Investigations of the compounds obtained from the plasmin-inhibitory-active extracts of W. ilvensis led to the isolation of two undescribed maleimide N-glycosides, an undescribed stilbenoid glycoside, and five undescribed acetylated flavonol bisdesmosides, together with 19 known compounds. The chemical structures of the isolated compounds were determined using spectroscopy. The absolute configurations of the sugar moieties were determined via HPLC after acid hydrolysis. Among the isolated compounds, some flavonoids and stilbenoid glycosides exhibited plasmin-inhibitory activity.
Identifiants
pubmed: 37598993
pii: S0031-9422(23)00242-X
doi: 10.1016/j.phytochem.2023.113826
pii:
doi:
Substances chimiques
Fibrinolysin
EC 3.4.21.7
Flavonoids
0
Glycosides
0
Plant Extracts
0
Phytochemicals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113826Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.