A unique association? A narcolepsy type 1 case comorbid with Primary Biliary Cholangitis.
Autoimmune diseases
Comorbidity
Narcolepsy type 1
Primary biliary cholangitis (PBC)
Journal
Sleep medicine
ISSN: 1878-5506
Titre abrégé: Sleep Med
Pays: Netherlands
ID NLM: 100898759
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
received:
30
05
2023
revised:
20
07
2023
accepted:
16
08
2023
medline:
25
9
2023
pubmed:
25
8
2023
entrez:
24
8
2023
Statut:
ppublish
Résumé
The aim of the study was to present a woman affected of a narcolepsy with cataplexy (narcolepsy type 1) comorbid with an asymptomatic Primary Biliary Cholangitis (PBC). The HLA haplotype was DRB1*15:01, DQA1*01:02, DQB1*06:02. The allele DQB1*06:02 has been considered until now protective for PBC and dual pathology has not been published. We think the important clinical message of the Case would be of continuing to monitor adults with narcolepsy type 1 for late complications that may be associated with other autoimmune conditions. Clinicians should be aware of the relationship between Narcolepsy and PBC. This highlights the need for screening and management in these individuals.
Identifiants
pubmed: 37619377
pii: S1389-9457(23)00305-2
doi: 10.1016/j.sleep.2023.08.015
pii:
doi:
Substances chimiques
HLA-DQ beta-Chains
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
180-182Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest No declared.