Organisation of the orthobunyavirus tripodal spike and the structural changes induced by low pH and K


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
21 09 2023
Historique:
received: 16 09 2022
accepted: 26 08 2023
medline: 25 9 2023
pubmed: 22 9 2023
entrez: 21 9 2023
Statut: epublish

Résumé

Following endocytosis, enveloped viruses employ the changing environment of maturing endosomes as cues to promote endosomal escape, a process often mediated by viral glycoproteins. We previously showed that both high [K

Identifiants

pubmed: 37735161
doi: 10.1038/s41467-023-41205-w
pii: 10.1038/s41467-023-41205-w
pmc: PMC10514341
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5885

Subventions

Organisme : Wellcome Trust
ID : 108466/Z/15/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 221524/Z/20/Z
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P001459/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : WT104918MA
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/T016159/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 090932/Z/09/Z
Pays : United Kingdom

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

Samantha Hover (S)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, Leeds, United Kingdom.
Astbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, United Kingdom.

Frank W Charlton (FW)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, Leeds, United Kingdom.
Astbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, United Kingdom.

Jan Hellert (J)

Centre for Structural Systems Biology, Leibniz-Institut für Virologie (LIV), Notkestraße 85, 22607, Hamburg, Germany.

Jessica J Swanson (JJ)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, Leeds, United Kingdom.
Astbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, United Kingdom.

Jamel Mankouri (J)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, Leeds, United Kingdom. bms9jm@gmail.com.
Astbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, United Kingdom. bms9jm@gmail.com.

John N Barr (JN)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, Leeds, United Kingdom. J.N.Barr@leeds.ac.uk.
Astbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, United Kingdom. J.N.Barr@leeds.ac.uk.

Juan Fontana (J)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, Leeds, United Kingdom. J.Fontana@leeds.ac.uk.
Astbury Centre for Structural and Molecular Biology, University of Leeds, LS2 9JT, Leeds, United Kingdom. J.Fontana@leeds.ac.uk.

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