Liquid phase microextraction based on natural deep eutectic solvents of psychoactive substances from biological fluids and natural waters.
Deep eutectic solvents
Drugs of abuse
Liquid phase microextraction
Psychoactive substances
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
15 Jan 2024
15 Jan 2024
Historique:
received:
28
06
2023
revised:
28
09
2023
accepted:
04
10
2023
medline:
9
11
2023
pubmed:
10
10
2023
entrez:
9
10
2023
Statut:
ppublish
Résumé
In this paper, natural deep eutectic solvents (NADES)-based for liquid phase microextraction (LPME) is proposed for the isolation of different psychoactive substances in water and biological fluids followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The NADES composition was optimized (L-menthol:octanoic acid, 1:2 M ratio) prior to the study of the extraction conditions such as sample and elution volumes, obtaining up to 16-fold preconcentration factor. Next, the quality parameters were studied including linearity from LOQs (0.0006-0.05 μg L
Identifiants
pubmed: 37813012
pii: S0039-9140(23)01028-7
doi: 10.1016/j.talanta.2023.125277
pii:
doi:
Substances chimiques
Deep Eutectic Solvents
0
Solvents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
125277Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.