Microdosimetry of a 62-MeV clinical proton beam with five detectors.
Journal
Radiation protection dosimetry
ISSN: 1742-3406
Titre abrégé: Radiat Prot Dosimetry
Pays: England
ID NLM: 8109958
Informations de publication
Date de publication:
11 Oct 2023
11 Oct 2023
Historique:
received:
07
07
2022
revised:
10
10
2022
accepted:
19
10
2022
medline:
1
11
2023
pubmed:
11
10
2023
entrez:
11
10
2023
Statut:
ppublish
Résumé
In proton therapy, most treatment planning systems (TPS) use a fixed relative biological effectiveness (RBE) of 1.1 all along the depth-dose profile. Innovative TPS are now investigated considering the variability of RBE with radiation quality. New TPS need an experimental verification in the quality assurance (QA) routine in clinics, but RBE data are usually obtained with radiobiological measurements that are time consuming and not suitable for daily QA. Microdosimetry is a useful tool based on physical measurements which can monitor the radiation quality. Several microdosimeters are available in different research institutions, which could potentially be used for the QA in TPS. In this study, the response functions of five detectors in the same 62-MeV proton Spread Out Bragg Peak is compared in terms of spectral distributions and their average values and microdosimetric RBE. Their different response function has been commented and must be considered in the clinical practice.
Identifiants
pubmed: 37819306
pii: 7306566
doi: 10.1093/rpd/ncac231
doi:
Substances chimiques
Protons
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1968-1972Subventions
Organisme : 5th Scientific Commission of the Italian Institute for Nuclear Physcs
Informations de copyright
© The Author(s) 2023. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.