Chromatin compartmentalization regulates the response to DNA damage.
Animals
Ataxia Telangiectasia Mutated Proteins
/ metabolism
Cell Line
Chromatin
/ genetics
DNA Breaks, Double-Stranded
DNA Damage
DNA Repair
DNA-Activated Protein Kinase
/ metabolism
G1 Phase
Histones
/ metabolism
Neoplasms
/ genetics
R-Loop Structures
Tumor Suppressor p53-Binding Protein 1
/ metabolism
Cell Compartmentation
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
07
11
2021
accepted:
12
09
2023
medline:
3
11
2023
pubmed:
19
10
2023
entrez:
18
10
2023
Statut:
ppublish
Résumé
The DNA damage response is essential to safeguard genome integrity. Although the contribution of chromatin in DNA repair has been investigated
Identifiants
pubmed: 37853125
doi: 10.1038/s41586-023-06635-y
pii: 10.1038/s41586-023-06635-y
pmc: PMC10620078
doi:
Substances chimiques
Ataxia Telangiectasia Mutated Proteins
EC 2.7.11.1
Chromatin
0
DNA-Activated Protein Kinase
EC 2.7.11.1
Histones
0
Tumor Suppressor p53-Binding Protein 1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
183-192Subventions
Organisme : Medical Research Council
ID : MC_UU_00025/6
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UP_A600_1024
Pays : United Kingdom
Organisme : NIH HHS
ID : S10 OD017993
Pays : United States
Organisme : Cancer Research UK
ID : 29252
Pays : United Kingdom
Organisme : Cancer Research UK
ID : 24388
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Type : ErratumIn
Informations de copyright
© 2023. The Author(s).
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