Phenylalanine-based fibrillar systems.
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
07 Dec 2023
07 Dec 2023
Historique:
medline:
11
12
2023
pubmed:
21
11
2023
entrez:
21
11
2023
Statut:
epublish
Résumé
Phenylketonuria (PKU) is an inborn metabolic disorder characterized by excess accumulation of phenylalanine (Phe) and its fibril formation, resulting in progressive intellectual disability. Several research groups have approached from various directions to understand the formation of toxic amyloid fibrils from the essential amino acid Phe. Different parameters like the nature of the solvent, pH, Phe concentration, temperature,
Substances chimiques
Phenylalanine
47E5O17Y3R
Peptides
0
Amyloid
0
Amino Acids
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM